Abnormal Left Ventricular Mechanics of Ventricular Ectopic Beats: Insights Into Origin and Coupling Interval in Premature Ventricular Contraction-Induced Cardiomyopathy [Original Articles]

Conclusions— PVCs with longer coupling intervals demonstrate more pronounced LV dyssynchrony, whereas PVC location has minimal impact. LV dyssynchrony cannot be attributed to prematurity or abnormal ventricular activation alone, but rather to a combination of both. This study suggests that late-coupled PVCs may cause a more severe cardiomyopathy if dyssynchrony is the leading mechanism responsible for PVC-induced cardiomyopathy.

http://circep.ahajournals.org/cgi/content/short/8/5/1194?rss=1

Source: Circulation: Arrhythmia and Electrophysiology - October 20, 2015 Category: Cardiology Authors: Potfay, J., Kaszala, K., Tan, A. Y., Sima, A. P., Gorcsan, J., Ellenbogen, K. A., Huizar, J. F. Tags: Other heart failure, Animal models of human disease, Arrythmias-basic studies, Echocardiography Original Articles Source Type: research