Filtered By:
Condition: Alzheimer's
This page shows you your search results in order of date. This is page number 17.
Order by Relevance | Date
Total 2642 results found since Jan 2013.
Nasu-Hakola Disease With Stroke-like Attack: A Case Report
Alzheimer Dis Assoc Disord. 2023 Feb 20. doi: 10.1097/WAD.0000000000000547. Online ahead of print.ABSTRACTHomozygous mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) gene are known to cause Nasu-Hakola disease, which is a rare cause of progressive presenile dementia. A 36-year-old woman presented with repetitive seizures, a 5-year history of progressive behavioral and cognitive changes, and an affected sibling. Magnetic resonance imaging of the brain revealed an ischemic lesion in the left medial temporal lobe. Extensive evaluation of juvenile stroke revealed that viral and autoimmune encephalitide...
Source: Alzheimer Disease and Associated Disorders - February 23, 2023 Category: Psychiatry Authors: Azra Rashid Nezhad Nahid Olfati Ali Shoeibi Fariborz Rezaei Talab Mohsen Soltani Sabi Source Type: research
Dietary energy restriction in neurological diseases: what’s new?
AbstractEnergy-restricted diet is a specific dietary regimen, including the continuous energy-restricted diet and the intermittent energy-restricted diet. It has been proven effective not only to reduce weight and extend the lifespan in animal models, but also to regulate the development and progression of various neurological diseases such as epilepsy, cerebrovascular diseases (stroke), neurodegenerative disorders (Alzheimer's disease and Parkinson's disease) and autoimmune diseases (multiple sclerosis). However, the mechanism in this field is still not clear and a systematic neurological summary is still missing. In this...
Source: European Journal of Nutrition - February 21, 2023 Category: Nutrition Source Type: research
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation
ConclusionsTREM2 transcripts can give rise to a heterogeneous pool of sTREM2 which acts to inhibit LTP. These results provide novel insight into the generation, regulation, and function of sTREM2 which fits into the complex biology of TREM2 and its role in human health and disease. Given that sTREM2 levels are linked to AD pathogenesis and progression, our finding that sTREM2 species interfere with LTP furthers our understanding about the role of TREM2 in AD.
Source: Genome Medicine - February 20, 2023 Category: Genetics & Stem Cells Source Type: research
Research on Diagnostic Markers for Post-Stroke Cognitive Impairment
CONCLUSION: Aβ42 and Hb in patients with PSCI were significantly lower than in the AD and PSCN groups, and were risk factors for PSCI. When the two are combined, the differential diagnosis performance may be improved.PMID:36795525
Source: Alternative Therapies in Health and Medicine - February 16, 2023 Category: Complementary Medicine Authors: Min Xu Lanqing Yang Zhe Zhong Min Ye Source Type: research
