Filtered By:
Specialty: Endocrinology

This page shows you your search results in order of date. This is page number 8.

Order by Relevance | Date

Total 648 results found since Jan 2013.

PCP protein inversin regulates testis function through changes in cytoskeletal organization of actin and microtubules
Endocrinology. 2022 Feb 1:bqac009. doi: 10.1210/endocr/bqac009. Online ahead of print.ABSTRACTInversin is an integrated component of the Frizzled (Fzd)/Dishevelled (Dvl)/Diversin planar cell polarity (PCP) complex that is known to work in concert with the Van Gogh-like protein (e.g., Vangl2)/Prickle PCP complex to support tissue and organ development including the brain, kidney, pancreas and others. However, with the exception of Dvl3 and Vangl2, other PCP proteins have not been investigated in the testis. Herein, we used the technique of RNAi to examine the role of inversin (Invs) in Sertoli cell and testis function by co...
Source: Endocrinology - February 2, 2022 Category: Endocrinology Authors: Linxi Li Sheng Gao Lingling Wang Tiao Bu Jinjin Chu Lixiu Lv Anam Tahir Baiping Mao Huitao Li Xiaoheng Li Yiyan Wang Xiaolong Wu Renshan Ge C Yan Cheng Source Type: research

PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease
ConclusionsThese findings provide evidence that PFKP may be a potential target for podocyte injury in DN and provide a rationale for applying podocyte glycolysis enhancing agents in patients with DKD.
Source: Frontiers in Endocrinology - January 14, 2022 Category: Endocrinology Source Type: research

Immunotherapy with a biologically active ICAM-1 mAb and an siRNA targeting TSHR in a BALB/c mouse model of Graves' disease
Conclusions These preliminary data suggest that both the biologically active ICAM-1 mAb and the siRNA targeting TSHR were effective. The ICAM-1 mAb exerted a better therapeutic effect than the siRNA targeting TSHR. Both treatments showed potential efficacy as novel treatments for GD and may therefore represent therapeutic options in addition to the existing drugs or interventions.PMID:34647608 | DOI:10.5603/EP.a2021.0087
Source: Endokrynologia Polska - October 14, 2021 Category: Endocrinology Authors: Xuan Wang Wei Liu Zhongying Rui Wei Zheng Jian Tan Ning Li Yang Yu Source Type: research