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Source: Molecular Medicine Reports
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Total 308 results found since Jan 2013.
Knockdown of ANLN inhibits the progression of lung adenocarcinoma via pyroptosis activation
In conclusion, ANLN represents an important gene and a promising therapeutic target for LUAD. Its potential as a therapeutic target makes it an interesting candidate for further exploration in the development of novel treatment strategies for LUAD.PMID:37539739 | PMC:PMC10433705 | DOI:10.3892/mmr.2023.13064
Source: Molecular Medicine Reports - August 4, 2023 Category: Molecular Biology Authors: Li Sheng Yanhai Kang Denglin Chen Linyang Shi Source Type: research
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain
In conclusion, in the present study, it was shown that MAGL regulated synovial macrophage polarization by inhibiting mitophagy in OA.PMID:37144506 | DOI:10.3892/mmr.2023.13004
Source: Molecular Medicine Reports - May 5, 2023 Category: Molecular Biology Authors: Chengyong Gu Mo Chen Xueyan Li Dechun Geng Chen Wang Source Type: research
Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes
Mol Med Rep. 2022 Aug;26(2):253. doi: 10.3892/mmr.2022.12769. Epub 2022 Jun 10.ABSTRACTFormulation of cationic liposomes is a key factor that determine the gene knockdown efficiency by cationic liposomes/siRNA complexes (siRNA lipoplexes). Here, to determine the optimal combination of cationic lipid and phospholipid in cationic liposomes for in vitro and in vivo gene knockdown using siRNA lipoplexes, three types of cationic lipid were used, namely 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), dimethyldioctadecylammonium bromide (DDAB) and 11-[(1,3-bis(dodecanoyloxy)-2-((dodecanoyloxy)methyl)propan-2-yl)amino]-N,N,N-tri...
Source: Molecular Medicine Reports - June 10, 2022 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Satomi Torii Kana Tomita Ayane Sagawa Nodoka Inoue Reo Yamagishi Kei-Ichi Ozaki Source Type: research
