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Source: Molecular Medicine Reports
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Total 308 results found since Jan 2013.
Retracted IQGAP1 ‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines
Mol Med Rep. 2023 Nov;28(5):207. doi: 10.3892/mmr.2023.13094. Epub 2023 Sep 21.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the GAPDH control western blotting data shown in Fig. 1C, and other western blotting data included in Figs. 2D and 7C and D, were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published elsewhere, prior to its s...
Source: Molecular Medicine Reports - September 21, 2023 Category: Molecular Biology Authors: Bo Diao Ying Liu Yi Zhang Jing Yu Jun Xie Guo-Zheng Xu Source Type: research
Resveratrol improves palmitic acid ‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells
In conclusion, RSV may improve PA‑induced IR in C2C12 cells through the DDIT4/mTOR/IRS‑1/PI3K/AKT/GLUT4 signaling pathway, as well as via improvements in glucose and lipid metabolism.PMID:37594055 | DOI:10.3892/mmr.2023.13068
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Xinyan Pan Chunqiao Liu Xing Wang Ming Zhao Zhimei Zhang Xuemei Zhang Chao Wang Guangyao Song Source Type: research
Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
Mol Med Rep. 2023 Oct;28(4):180. doi: 10.3892/mmr.2023.13067. Epub 2023 Aug 18.ABSTRACTPreviously, using three types of cationic lipids, the effect of phospholipids in liposomal formulations on gene-knockdown efficacy was determined after in vitro and in vivo transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) containing various cationic lipids and phospholipids. In the present study, six other types of cationic lipids, namely N,N-dimethyl-N-tetradecyltetradecan-1-aminium bromide, N-hexadecyl-N,N-dimethylhexadecan-1-aminium bromide (DC-1-16), 2-[bis{2-(tetradecanoyloxy)ethyl}amino...
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Aya Aoki Momoka Ezaki Hana Sakai Kei-Ichi Ozaki Source Type: research
Resveratrol improves palmitic acid ‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells
In conclusion, RSV may improve PA‑induced IR in C2C12 cells through the DDIT4/mTOR/IRS‑1/PI3K/AKT/GLUT4 signaling pathway, as well as via improvements in glucose and lipid metabolism.PMID:37594055 | DOI:10.3892/mmr.2023.13068
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Xinyan Pan Chunqiao Liu Xing Wang Ming Zhao Zhimei Zhang Xuemei Zhang Chao Wang Guangyao Song Source Type: research
Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
Mol Med Rep. 2023 Oct;28(4):180. doi: 10.3892/mmr.2023.13067. Epub 2023 Aug 18.ABSTRACTPreviously, using three types of cationic lipids, the effect of phospholipids in liposomal formulations on gene-knockdown efficacy was determined after in vitro and in vivo transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) containing various cationic lipids and phospholipids. In the present study, six other types of cationic lipids, namely N,N-dimethyl-N-tetradecyltetradecan-1-aminium bromide, N-hexadecyl-N,N-dimethylhexadecan-1-aminium bromide (DC-1-16), 2-[bis{2-(tetradecanoyloxy)ethyl}amino...
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Aya Aoki Momoka Ezaki Hana Sakai Kei-Ichi Ozaki Source Type: research
Resveratrol improves palmitic acid ‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells
In conclusion, RSV may improve PA‑induced IR in C2C12 cells through the DDIT4/mTOR/IRS‑1/PI3K/AKT/GLUT4 signaling pathway, as well as via improvements in glucose and lipid metabolism.PMID:37594055 | DOI:10.3892/mmr.2023.13068
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Xinyan Pan Chunqiao Liu Xing Wang Ming Zhao Zhimei Zhang Xuemei Zhang Chao Wang Guangyao Song Source Type: research
Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
Mol Med Rep. 2023 Oct;28(4):180. doi: 10.3892/mmr.2023.13067. Epub 2023 Aug 18.ABSTRACTPreviously, using three types of cationic lipids, the effect of phospholipids in liposomal formulations on gene-knockdown efficacy was determined after in vitro and in vivo transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) containing various cationic lipids and phospholipids. In the present study, six other types of cationic lipids, namely N,N-dimethyl-N-tetradecyltetradecan-1-aminium bromide, N-hexadecyl-N,N-dimethylhexadecan-1-aminium bromide (DC-1-16), 2-[bis{2-(tetradecanoyloxy)ethyl}amino...
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Aya Aoki Momoka Ezaki Hana Sakai Kei-Ichi Ozaki Source Type: research
Resveratrol improves palmitic acid ‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells
In conclusion, RSV may improve PA‑induced IR in C2C12 cells through the DDIT4/mTOR/IRS‑1/PI3K/AKT/GLUT4 signaling pathway, as well as via improvements in glucose and lipid metabolism.PMID:37594055 | DOI:10.3892/mmr.2023.13068
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Xinyan Pan Chunqiao Liu Xing Wang Ming Zhao Zhimei Zhang Xuemei Zhang Chao Wang Guangyao Song Source Type: research
Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
Mol Med Rep. 2023 Oct;28(4):180. doi: 10.3892/mmr.2023.13067. Epub 2023 Aug 18.ABSTRACTPreviously, using three types of cationic lipids, the effect of phospholipids in liposomal formulations on gene-knockdown efficacy was determined after in vitro and in vivo transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) containing various cationic lipids and phospholipids. In the present study, six other types of cationic lipids, namely N,N-dimethyl-N-tetradecyltetradecan-1-aminium bromide, N-hexadecyl-N,N-dimethylhexadecan-1-aminium bromide (DC-1-16), 2-[bis{2-(tetradecanoyloxy)ethyl}amino...
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Aya Aoki Momoka Ezaki Hana Sakai Kei-Ichi Ozaki Source Type: research
Resveratrol improves palmitic acid ‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells
In conclusion, RSV may improve PA‑induced IR in C2C12 cells through the DDIT4/mTOR/IRS‑1/PI3K/AKT/GLUT4 signaling pathway, as well as via improvements in glucose and lipid metabolism.PMID:37594055 | DOI:10.3892/mmr.2023.13068
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Xinyan Pan Chunqiao Liu Xing Wang Ming Zhao Zhimei Zhang Xuemei Zhang Chao Wang Guangyao Song Source Type: research
Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
Mol Med Rep. 2023 Oct;28(4):180. doi: 10.3892/mmr.2023.13067. Epub 2023 Aug 18.ABSTRACTPreviously, using three types of cationic lipids, the effect of phospholipids in liposomal formulations on gene-knockdown efficacy was determined after in vitro and in vivo transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) containing various cationic lipids and phospholipids. In the present study, six other types of cationic lipids, namely N,N-dimethyl-N-tetradecyltetradecan-1-aminium bromide, N-hexadecyl-N,N-dimethylhexadecan-1-aminium bromide (DC-1-16), 2-[bis{2-(tetradecanoyloxy)ethyl}amino...
Source: Molecular Medicine Reports - August 18, 2023 Category: Molecular Biology Authors: Yoshiyuki Hattori Min Tang Aya Aoki Momoka Ezaki Hana Sakai Kei-Ichi Ozaki Source Type: research
Knockdown of ANLN inhibits the progression of lung adenocarcinoma via pyroptosis activation
In conclusion, ANLN represents an important gene and a promising therapeutic target for LUAD. Its potential as a therapeutic target makes it an interesting candidate for further exploration in the development of novel treatment strategies for LUAD.PMID:37539739 | DOI:10.3892/mmr.2023.13064
Source: Molecular Medicine Reports - August 4, 2023 Category: Molecular Biology Authors: Li Sheng Yanhai Kang Denglin Chen Linyang Shi Source Type: research
