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Infectious Disease: COVID-19

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Assuring the Groundwork for Success: Mentorship, Sponsorship, and Allyship for Practicing Anesthesiologists
Anesth Analg. 2023 Oct 1;137(4):754-762. doi: 10.1213/ANE.0000000000006646. Epub 2023 Sep 5.ABSTRACTThe challenges facing the health care industry in the post-coronavirus disease 2019 (COVID-19) pandemic world are numerous, jeopardizing wellness, and performance. Maintaining engagement and fulfillment of anesthesiologists in their work is now a critical issue in various practice settings: academic, private practice, and corporate medicine. In this article, we offer insights on how mentorship, sponsorship, and allyship are important in the advancement of the anesthesiology workforce including women and underrepresented mino...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Mofya S Diallo Crystal C Wright Alice A Tolbert Coombs Thomas R Vetter Source Type: research

Lasting Impacts of the COVID-19 Pandemic on Breast Cancer Diagnosis and Treatment in the United States
Surg Oncol Clin N Am. 2023 Oct;32(4):811-819. doi: 10.1016/j.soc.2023.05.010. Epub 2023 May 10.ABSTRACTThe COVID-19 pandemic was an unprecedented time that placed unique challenges on the screening and treatment of breast cancer in the United States. Collaboration among medical disciplines and societies provided guidelines and strategies to mitigate the exposure of patients and medical providers to the virus and provide optimal care. We discuss the changes that the pandemic had on the multidisciplinary management of breast cancer.PMID:37714645 | PMC:PMC10169575 | DOI:10.1016/j.soc.2023.05.010
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Jenna L Sturz Judy C Boughey Source Type: research

Effect of work from home and employee mental health through mediating role of workaholism and work-family balance
This study provides real-world guidance to human resource managers on how to prioritize composite-level interventions at all levels of the university to create highly satisfied employees, provide a good working environment, and improve employees' mental health.ORIGINALITY/VALUE: Many researches have been done on the relationship between work-from-home and employee mental health, but relatively few have looked at how work-life balance and workaholism play a role in how work-from-home affects employees' mental health. This study fills a need in the academic and practitioner literature by investigating the relationship betwee...
Source: The International Journal of Social Psychiatry - September 15, 2023 Category: Psychiatry Authors: Chitra Krishnan Shailender Singh Mubashir Majid Baba Source Type: research

Modelling the rate of trainees transitioning to Fellowship before achieving competence under the RANZCP's Alternative Assessment Pathway to the Objective Structured Clinical Examination
CONCLUSIONS: Given possible increases in pre-competent trainees progressing to Fellowship while alternatives to the OSCE are finalised, confidence in the RANZCP's training program demands robust public analyses of those alternatives.PMID:37714141 | DOI:10.1177/10398562231202120
Source: Australasian Psychiatry - September 15, 2023 Category: Psychiatry Authors: Andrew Amos Michael James Weightman Edward Miller Source Type: research

Achieving COVID-19 zero without lockdown, January 2020 to March 2022: The Taiwan model explained
J Formos Med Assoc. 2023 Sep 13:S0929-6646(23)00345-5. doi: 10.1016/j.jfma.2023.09.001. Online ahead of print.ABSTRACTDespite never imposing a lockdown, Taiwan achieved COVID-19 zero, with reporting only 56 local coronavirus disease 2019 (COVID-19) cases after testing 126,987 individuals in 2020, and further contained a large outbreak rapidly and successfully in 2021. At the onset of the COVID-19 pandemic, our infectious disease modeling results indicated that testing and contact tracing alone would fail to contain the pandemic. However, by supplementing this approach with general public surgical mask-wearing, the reproduc...
Source: J Formos Med Assoc - September 15, 2023 Category: General Medicine Authors: Yi-Hsuan Chen Chi-Tai Fang Source Type: research

Acute invasive fungal rhinosinusitis in post-COVID-19 patients in Vietnam
CONCLUSION: The presence of meningitis upon initial diagnosis is related to a significantly higher chance of developing a fatal outcome and should be considered, especially in AIFR patients previously treated for COVID-19 infections. Early diagnosis, early use of antifungal agents, aggressive surgical debridement, and control of comorbid conditions remain crucial in managing AIFR.PMID:37714767 | DOI:10.1016/j.jfma.2023.08.030
Source: J Formos Med Assoc - September 15, 2023 Category: General Medicine Authors: Ly Xuan Quang Truong Thanh Tam Luong Huu Dang Yen-Chun Chen Shih-Han Hung Tran Thanh Tai Nguyen Le Vu Hoang Nguyen Van Thanh Source Type: research

< sup > 18 < /sup > F-mFBG imaging for COVID-19-induced cardiac sympathetic innervation impairment
Eur J Nucl Med Mol Imaging. 2023 Sep 15. doi: 10.1007/s00259-023-06432-9. Online ahead of print.NO ABSTRACTPMID:37712995 | DOI:10.1007/s00259-023-06432-9
Source: Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Xiao Zhang Mengyan Hu Fei Kang Jing Wang Xiaoli Lan Source Type: research

A synthetic delivery vector for mucosal vaccination
Biomaterials. 2023 Sep 5;302:122298. doi: 10.1016/j.biomaterials.2023.122298. Online ahead of print.ABSTRACTThe success of mRNA-based vaccines during the Covid-19 pandemic has highlighted the value of this new platform for vaccine development against infectious disease. However, the CD8+ T cell response remains modest with mRNA vaccines, and these do not induce mucosal immunity, which would be needed to prevent viral spread in the healthy population. To address this drawback, we developed a dendritic cell targeting mucosal vaccination vector, the homopentameric STxB. Here, we describe the highly efficient chemical synthesi...
Source: Biomaterials - September 15, 2023 Category: Materials Science Authors: Anne Billet Justine Hadjerci Thi Tran Pascal Kessler Jonathan Ulmer Gilles Mourier Marine Ghazarian Anthony Gonzalez Robert Thai Pauline Urquia Anne-C écile Van Baelen Annalisa Meola Ignacio Fernandez St éphanie Deville-Foillard Ewan MacDonald L éa Pao Source Type: research

Factors associated with depression among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis
Psychol Med. 2023 Sep 15:1-10. doi: 10.1017/S0033291723002271. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a profound impact on the mental health of healthcare workers (HCWs). We aimed to identify the factors associated with depression among HCWs during the pandemic. We conducted literature search using eight electronic databases up to July 27 2022. Observational studies with more than 200 participants investigating correlates of depression in HCWs after COVID-19 outbreak were included. We used fixed- and random-effects models to pool odds ratios (ORs) across studies, and Cochran's chi-squared test and I 2 ...
Source: Psychological Medicine - September 15, 2023 Category: Psychiatry Authors: Haoyu Tian Tianci Qiao Jing Teng Chen Kang Jia Ke Lili Shan Mengting Li Chun Shen Yan Han Source Type: research

Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection
In conclusion, combining AM and CV was effective in acting as an oral adjuvant with the mRNA vaccine BNT162b2 to improve the antigen binding activities against SARS-CoV-2 ancestral and variant SARS-CoV-2 spike proteins, probably via trained immunity of macrophages and dendritic cells.PMID:37713617 | DOI:10.1093/jleuko/qiad106
Source: Journal of Leukocyte Biology - September 15, 2023 Category: Hematology Authors: Ben Chung-Lap Chan Peiting Li Miranda Sin-Man Tsang Johnny Chun-Chau Sung Keith Wai-Yeung Kwong Tao Zheng Sharon Sze-Man Hon Ching-Po Lau Ronald Chi-Yan Ho Fang Chen Clara Bik-San Lau Ping-Chung Leung Chun-Kwok Wong Source Type: research

Lasting Impacts of the COVID-19 Pandemic on Breast Cancer Diagnosis and Treatment in the United States
Surg Oncol Clin N Am. 2023 Oct;32(4):811-819. doi: 10.1016/j.soc.2023.05.010. Epub 2023 May 10.ABSTRACTThe COVID-19 pandemic was an unprecedented time that placed unique challenges on the screening and treatment of breast cancer in the United States. Collaboration among medical disciplines and societies provided guidelines and strategies to mitigate the exposure of patients and medical providers to the virus and provide optimal care. We discuss the changes that the pandemic had on the multidisciplinary management of breast cancer.PMID:37714645 | PMC:PMC10169575 | DOI:10.1016/j.soc.2023.05.010
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Jenna L Sturz Judy C Boughey Source Type: research

Investigation of the relationship between monocyte chemoattractant protein 1 rs1024611 variant and severity of COVID-19
CONCLUSION: The MCP-1 gene polymorphism had no impact on COVID-19 severity. However, to confirm these results, a large-scale study needs to be conducted.PMID:37713941 | DOI:10.1016/j.cyto.2023.156367
Source: Cytokine - September 15, 2023 Category: Molecular Biology Authors: Fatemeh Azarfar Bahareh Abbasi Amir Jalali Mohammad Hadi Abbasian Source Type: research

Erratum: Utility of in-house and commercial PCR assay in diagnosis of Covid-19 associated mucormycosis in an emergency setting in a tertiary care center
J Med Microbiol. 2023 Sep;72(9). doi: 10.1099/jmm.0.001754.NO ABSTRACTPMID:37712654 | DOI:10.1099/jmm.0.001754
Source: Journal of Medical Microbiology - September 15, 2023 Category: Microbiology Authors: Mragnayani Pandey Janya Sachdev Renu Kumari Yadav Neha Sharad Anupam Kanodia Jaya Biswas R Sruti Janani Sonakshi Gupta Gagandeep Singh Meera Ekka Bhaskar Rana Sudesh Gourav Alok Thakar Ashutosh Biswas Kapil Sikka Purva Mathur Neelam Pushker Viveka P Jyots Source Type: research

Cardiac Tamponade Secondary to Hemorrhagic Pericardial Effusion: A Complication of STEMI
Conclusion: The differential for hemodynamic compromise in a patient with STEMI is broad, but quickly distinguishing pump failure from other life-threatening causes of shock is imperative to dictate time-sensitive management decisions. The presence of a hemorrhagic pericardial effusion in the setting of STEMI is a surrogate marker for a severe infarct and can help the bedside physician determine whether a patient will be better served in the catheterization lab for revascularization or in the operating room for surgical repair.PMID:37711482 | PMC:PMC10498953 | DOI:10.31486/toj.23.0023
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Marvin Kajy Amy Rechenberg Connor Kerndt Kevin Wolschleger Source Type: research

Extracellular Vesicles and Endocannabinoid Signaling in Patients with COVID-19
Conclusions: EVs carry immunologically functional endocannabinoids in COVID-19 along with miRNAs which may regulate the expression of mRNA transcripts involved in the regulation of endocannabinoid signaling and metabolism. This mechanism could fine-tune and adapt endocannabinoid effects in recipient cells in relationship to the present biological context.PMID:37713293 | DOI:10.1089/can.2023.0040
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Florian Brandes Annekathrin M Keiler Benedikt Kirchner Melanie Borrmann Jean-No ël Billaud Marlene Reithmair Matthias Klein Patrizia Campolongo Detlef Thieme Michael W Pfaffl Gustav Schelling Agnes S Meidert Source Type: research