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Infectious Disease: COVID-19
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COVID-19 Booster Uptake: Are Hesitant Adopters Less Likely to Get a Booster Shot Than Nonhesitant Adopters?
Behav Med. 2023 Sep 18:1-9. doi: 10.1080/08964289.2023.2249168. Online ahead of print.ABSTRACTThe main objective of this study was to assess whether hesitancy toward receiving the initial COVID-19 vaccine was associated with uptake of the COVID-19 booster several months after it became available to all US adults. We ask whether hesitancy toward the initial COVID-19 vaccine was significantly associated with lower odds of COVID-19 booster uptake among adults. We test this association within the context of the highly rural state of Arkansas. By January 2022, the US had set a global record of nearly 1 million daily cases. The ...
Source: Behavioral Medicine - September 18, 2023 Category: Psychiatry Authors: Don E Willis Ramey Moore James P Selig Sheena CarlLee Morgan P Gurel-Headley Lawrence E Cornett Pearl A McElfish Source Type: research
Prostaglandin E < sub > 2 < /sub > and myocarditis; friend or foe?
Biochem Pharmacol. 2023 Sep 16:115813. doi: 10.1016/j.bcp.2023.115813. Online ahead of print.ABSTRACTThis review article summarizes the role of prostaglandin E2 (PGE2) and its receptors (EP1-EP4) as it relates to the inflammatory cardiomyopathy, myocarditis. During the COVID-19 pandemic, the onset of myocarditis in a subset of patients prompted a debate on the use of nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, which act to inhibit the actions of prostaglandins. This review aims to further understanding of the role of PGE2 in the pathogenesis or protection of the myocardium in myocarditis. Inflammatory ca...
Source: Biochemical Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Timothy D Bryson Pamela Harding Source Type: research
Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research
General practice as a place to receive help for domestic abuse during the COVID-19 pandemic: a qualitative interview study in England and Wales
CONCLUSION: Perspectives of patients and their families affected by DVA should be prioritised in general practice service planning, including during periods of transition and change.PMID:37722856 | DOI:10.3399/BJGP.2022.0528
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Elizabeth Emsley Caroline Coope Emma Williamson Estela Capelas Barbosa Gene Feder Eszter Szilassy Source Type: research
Monitoring strategy of COVID-19 vaccination in dialysis patients based on a multiplex immunodot method: The CovidDial study
CONCLUSION: Three doses of mRNA-1273 vaccine induce a robust but time-limited immunologic response in dialysis patients. Lower anti-spike antibodies titers after initial vaccination are associated with a higher risk to subsequently contract SARS-CoV-2, even beyond 6 months.PMID:37718617 | DOI:10.1111/sdi.13175
Source: Seminars in Dialysis - September 18, 2023 Category: Urology & Nephrology Authors: Fr édéric Debelle Vo Thanh Phuong Nguyen Laurence Boitquin Miguel-Ange Guillen-Anaya Fabrice Gankam Anne-Emilie Decl èves CoviDial study group Source Type: research
Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2)
CONCLUSION: Nirmatrelvir-ritonavir and molnupiravir probably improve outcomes for outpatients with mild to moderate COVID-19.PRIMARY FUNDING SOURCE: American College of Physicians. (PROSPERO: CRD42023406456).PMID:37722115 | DOI:10.7326/M23-1626
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Isolde Sommer Dominic Ledinger Kylie Thaler Andreea Dobrescu Emma Persad Martin Fangmeyer Irma Klerings Gerald Gartlehner Source Type: research
Web Exclusive. Annals Video Summary - Outpatient Treatment of Confirmed COVID-19
Ann Intern Med. 2023 Sep 19:eM232064. doi: 10.7326/M23-2064. Online ahead of print.NO ABSTRACTPMID:37722114 | DOI:10.7326/M23-2064
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Source Type: research
Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2)
Ann Intern Med. 2023 Sep 19. doi: 10.7326/M23-1636. Online ahead of print.ABSTRACTDESCRIPTION: Evidence for the use of outpatient treatments in adults with confirmed COVID-19 continues to evolve with new data. This is version 2 of the American College of Physicians (ACP) living, rapid practice points focusing on 22 outpatient treatments for COVID-19, specifically addressing the dominant SARS-CoV-2 Omicron variant.METHODS: The Population Health and Medical Science Committee (formerly the Scientific Medical Policy Committee) developed this version of the living, rapid practice points on the basis of a living, rapid review do...
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Amir Qaseem Jennifer Yost George M Abraham Rebecca Andrews Janet A Jokela Matthew C Miller Linda L Humphrey Population Health and Medical Science Committee of the American College of Physicians Source Type: research
Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2)
CONCLUSION: Nirmatrelvir-ritonavir and molnupiravir probably improve outcomes for outpatients with mild to moderate COVID-19.PRIMARY FUNDING SOURCE: American College of Physicians. (PROSPERO: CRD42023406456).PMID:37722115 | DOI:10.7326/M23-1626
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Isolde Sommer Dominic Ledinger Kylie Thaler Andreea Dobrescu Emma Persad Martin Fangmeyer Irma Klerings Gerald Gartlehner Source Type: research
Web Exclusive. Annals Video Summary - Outpatient Treatment of Confirmed COVID-19
Ann Intern Med. 2023 Sep 19:eM232064. doi: 10.7326/M23-2064. Online ahead of print.NO ABSTRACTPMID:37722114 | DOI:10.7326/M23-2064
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Source Type: research
Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2)
Ann Intern Med. 2023 Sep 19. doi: 10.7326/M23-1636. Online ahead of print.ABSTRACTDESCRIPTION: Evidence for the use of outpatient treatments in adults with confirmed COVID-19 continues to evolve with new data. This is version 2 of the American College of Physicians (ACP) living, rapid practice points focusing on 22 outpatient treatments for COVID-19, specifically addressing the dominant SARS-CoV-2 Omicron variant.METHODS: The Population Health and Medical Science Committee (formerly the Scientific Medical Policy Committee) developed this version of the living, rapid practice points on the basis of a living, rapid review do...
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Amir Qaseem Jennifer Yost George M Abraham Rebecca Andrews Janet A Jokela Matthew C Miller Linda L Humphrey Population Health and Medical Science Committee of the American College of Physicians Source Type: research
COVID-19 Booster Uptake: Are Hesitant Adopters Less Likely to Get a Booster Shot Than Nonhesitant Adopters?
Behav Med. 2023 Sep 18:1-9. doi: 10.1080/08964289.2023.2249168. Online ahead of print.ABSTRACTThe main objective of this study was to assess whether hesitancy toward receiving the initial COVID-19 vaccine was associated with uptake of the COVID-19 booster several months after it became available to all US adults. We ask whether hesitancy toward the initial COVID-19 vaccine was significantly associated with lower odds of COVID-19 booster uptake among adults. We test this association within the context of the highly rural state of Arkansas. By January 2022, the US had set a global record of nearly 1 million daily cases. The ...
Source: Behavioral Medicine - September 18, 2023 Category: Psychiatry Authors: Don E Willis Ramey Moore James P Selig Sheena CarlLee Morgan P Gurel-Headley Lawrence E Cornett Pearl A McElfish Source Type: research
Prostaglandin E < sub > 2 < /sub > and myocarditis; friend or foe?
Biochem Pharmacol. 2023 Sep 16:115813. doi: 10.1016/j.bcp.2023.115813. Online ahead of print.ABSTRACTThis review article summarizes the role of prostaglandin E2 (PGE2) and its receptors (EP1-EP4) as it relates to the inflammatory cardiomyopathy, myocarditis. During the COVID-19 pandemic, the onset of myocarditis in a subset of patients prompted a debate on the use of nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, which act to inhibit the actions of prostaglandins. This review aims to further understanding of the role of PGE2 in the pathogenesis or protection of the myocardium in myocarditis. Inflammatory ca...
Source: Biochemical Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Timothy D Bryson Pamela Harding Source Type: research
Treatments for COVID-19
Annu Rev Med. 2023 Sep 18. doi: 10.1146/annurev-med-052422-020316. Online ahead of print.ABSTRACTThe treatment for COVID-19 has evolved rapidly since the start of the pandemic and now consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir and nirmatrelvir-ritonavir, have proved to be most useful earlier in illness (e.g., as outpatient therapy) and for less severe disease. Immunomodulatory therapy, such as dexamethasone and interleukin-6 or Janus kinase inhibitors, are most useful in severe disease or critical illness. The role of anti-SARS-CoV-2 monoclonal antibodies has diminished because...
Source: Annual Review of Medicine - September 18, 2023 Category: General Medicine Authors: Hayden S Andrews Jonathan D Herman Rajesh T Gandhi Source Type: research
Impact of COVID-19 on the self-esteem, psychological and dental esthetics of dental students
CONCLUSION: The pandemic, aside from affecting the health of individuals worldwide, also badly affected the well-being, mental health, and self-esteem of the dental students. Dental aesthetics plays a crucial role in the mental wellbeing and self-esteem of the students.PMID:37718829 | DOI:10.3233/WOR-220627
Source: Work - September 18, 2023 Category: Occupational Health Authors: Firas K Alqarawi Beenish Fatima Alam Talha Nayab Sami Alshehry Badr Al-Jandan Faisal Fahim Saqib Ali Source Type: research
