Log in to search using one of your social media accounts:

 

Self ‐cannulation of the vascular access in home hemodialysis: Overcoming patient‐level barriers
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 11, 2018 Category: Hematology Authors: Frank L. Ward , Rose Faratro , Rory F. McQuillan Source Type: research

Self-cannulation of the vascular access in home hemodialysis: Overcoming patient-level barriers.
Abstract Patients with end-stage kidney disease who are considering home hemodialysis (HHD) face the challenge of learning to self-cannulate their arteriovenous access. Current practice discourages the use of tunneled central venous catheters, with recent indications that self-cannulating patients have superior outcomes. Patient-level barriers do not appear to preclude a successful HHD program and should not be viewed as insurmountable by healthcare staff or patients. The healthcare team must address patient fears while instructing the patient to perform self-cannulation safely. Identification and understanding of...
Source: Seminars in Dialysis - May 11, 2018 Category: Urology & Nephrology Authors: Ward FL, Faratro R, McQuillan RF Tags: Semin Dial Source Type: research

Vaccination practices in dialysis patients: A narrative review
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 9, 2018 Category: Hematology Authors: Georges Kosmadakis , Julie Albaret , Enrique Da Costa Correia , Frederic Somda , Didier Aguilera Source Type: research

Vaccination practices in dialysis patients: A narrative review.
Abstract In a period of turmoil concerning vaccination practices, there is a serious conflict between scientifically reasonable, evidence-based guidelines and the far-fetched rumors or misconceptions concerning the vaccination practices in the general population. When a significant portion of the medical and paramedical personnel may be deliberately unvaccinated against common biological agents, achieving effective vaccination rates in the dialysis population may be complicated. Vaccination rates are unacceptably low in dialysis patients and seroconversion rates are even lower; further, serological follow-up is ge...
Source: Seminars in Dialysis - May 9, 2018 Category: Urology & Nephrology Authors: Kosmadakis G, Albaret J, Correia EDC, Somda F, Aguilera D Tags: Semin Dial Source Type: research

Acute kidney injury: Epidemiology, outcomes, complications, and therapeutic strategies
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 8, 2018 Category: Hematology Authors: Shigeo Negi , Daisuke Koreeda , Sou Kobayashi , Takuro Yano , Koichi Tatsuta , Toru Mima , Takashi Shigematsu , Masaki Ohya Source Type: research

Incremental dialysis for preserving residual kidney function —Does one size fit all when initiating dialysis?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 8, 2018 Category: Hematology Authors: Anna T. Mathew , Yoshitsugu Obi , Connie M. Rhee , Jason A. Chou , Kamyar Kalantar ‐Zadeh Source Type: research

Planning and evaluation for vascular access in the elderly
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 8, 2018 Category: Hematology Authors: Candice Halinski , Holly M. Koncicki Source Type: research

Acute kidney injury: Epidemiology, outcomes, complications, and therapeutic strategies.
Abstract Acute kidney injury (AKI) is one of the most common serious complications for all hospital admissions, with its incidence increasing among hospitalized patients, particularly those in the intensive care unit. Despite significant improvements in critical care and dialysis technology, AKI is associated with an increased risk of short- and long-term mortality, prolonged hospital stays, and dialysis dependence. These risks are particularly relevant for critically ill patients with AKI severe enough to require renal replacement therapy (RRT). No specific pharmacologic treatment has been established to treat AK...
Source: Seminars in Dialysis - May 8, 2018 Category: Urology & Nephrology Authors: Negi S, Koreeda D, Kobayashi S, Yano T, Tatsuta K, Mima T, Shigematsu T, Ohya M Tags: Semin Dial Source Type: research

Planning and evaluation for vascular access in the elderly.
This article reviews access considerations for AVF placement in the elderly population and considers the possibility that the fistula first approach to vascular access should not be an absolute. PMID: 29736915 [PubMed - as supplied by publisher] (Source: Seminars in Dialysis)
Source: Seminars in Dialysis - May 8, 2018 Category: Urology & Nephrology Authors: Halinski C, Koncicki HM Tags: Semin Dial Source Type: research

Current and potential therapeutic strategies for the management of vascular calcification in patients with chronic kidney disease including those on dialysis.
Abstract Patients with CKD have accelerated vascular stiffening contributing significantly to excess cardiovascular morbidity and mortality. Much of the arterial stiffening is thought to involve vascular calcification (VC), but the pathogenesis of this phenomenon is complex, resulting from a disruption of the balance between promoters and inhibitors of calcification in a uremic milieu, along with derangements in calcium and phosphate metabolic pathways. Management of traditional cardiovascular risk factors to reduce VC may be influential but has not been shown to significantly improve mortality. Control of mineral...
Source: Seminars in Dialysis - May 7, 2018 Category: Urology & Nephrology Authors: Ruderman I, Holt SG, Hewitson TD, Smith ER, Toussaint ND Tags: Semin Dial Source Type: research

Incremental dialysis for preserving residual kidney function-Does one size fit all when initiating dialysis?
Abstract While many patients have substantial residual kidney function (RKF) when initiating hemodialysis (HD), most patients with end stage renal disease in the United States are initiated on 3-times per week conventional HD regimen, with little regard to RKF or patient preference. RKF is associated with many benefits including survival, volume control, solute clearance, and reduced inflammation. Several strategies have been recommended to preserve RKF after HD initiation, including an incremental approach to HD initiation. Incremental HD prescriptions are personalized to achieve adequate volume control and solut...
Source: Seminars in Dialysis - May 7, 2018 Category: Urology & Nephrology Authors: Mathew AT, Obi Y, Rhee CM, Chou JA, Kalantar-Zadeh K Tags: Semin Dial Source Type: research

Current and potential therapeutic strategies for the management of vascular calcification in patients with chronic kidney disease including those on dialysis
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 7, 2018 Category: Hematology Authors: Irene Ruderman , Stephen G. Holt , Tim D. Hewitson , Edward R. Smith , Nigel D. Toussaint Source Type: research

Briefly Noted
Seminars in Dialysis,Volume 31, Issue 3, Page 309-310, May/June 2018. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 4, 2018 Category: Hematology Authors: Richard A. Sherman Source Type: research

Issue Information
Seminars in Dialysis,Volume 31, Issue 3, Page 197-198, May/June 2018. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 4, 2018 Category: Hematology Source Type: research

Patient ‐to‐patient peer mentor support in dialysis: Improving the patient experience
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - May 3, 2018 Category: Hematology Authors: Paul N. Bennett , Jennifer St. Clair Russell , Jug Atwal , Lashone Brown , Brigitte Schiller Source Type: research

Patient-to-patient peer mentor support in dialysis: Improving the patient experience.
Abstract Greater focus on patient-reported outcome measures for dialysis patients and an increased patient engagement focus has highlighted a lack of formal patient-generated strategies. Patient-to-patient peer mentoring is one approach that may improve the outcomes for people receiving dialysis. This review aims to synthesize quantitative and qualitative studies investigating dialysis-associated patient-to-patient peer mentor support among adults with chronic kidney disease and end stage kidney disease. Research studies describe the benefits of peer mentor programs in dialysis to include: improved goal setting, d...
Source: Seminars in Dialysis - May 2, 2018 Category: Urology & Nephrology Authors: Bennett PN, St Clair Russell J, Atwal J, Brown L, Schiller B Tags: Semin Dial Source Type: research

ESRD ‐induced dyslipidemia—Should management of lipid disorders differ in dialysis patients?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 30, 2018 Category: Hematology Authors: Hamid Moradi , Elani Streja , Nosratola D. Vaziri Source Type: research

ESRD-induced dyslipidemia-Should management of lipid disorders differ in dialysis patients?
Abstract Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Although numerous modifiable risk factors in the pathogenesis of CVD and its associated mortality have been identified, dyslipidemia remains to be a key focus for therapy. In this regard, significant progress has been made in reducing cardiovascular mortality via the use of lipid-lowering agents such as HMG CoA reductase inhibitors (statins). Yet, despite the disproportionate risk of CVD and mortality in patients with advanced chronic and end stage renal disease (ESRD), treatment of dyslipidemia in this patient population ...
Source: Seminars in Dialysis - April 29, 2018 Category: Urology & Nephrology Authors: Moradi H, Streja E, Vaziri ND Tags: Semin Dial Source Type: research

Hemodialysis: A model for extreme physiology in a vulnerable patient population
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 20, 2018 Category: Hematology Authors: Jeroen P. Kooman , Krassimir Katzarski , Frank M. van der Sande , Karel M. Leunissen , Peter Kotanko Source Type: research

Does peritoneal dialysis have a role in urgent ‐start end‐stage kidney disease?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 20, 2018 Category: Hematology Authors: Rory F. McQuillan , Charmaine E. Lok Source Type: research

Should phosphate management be limited to the KDIGO/ KDOQI guidelines?
Abstract Hyperphosphatemia is a common complication of CKD. Prior to development of overt hyperphosphatemia, there are several adaptive mechanisms that occur to maintain normal phosphorus equilibrium in patients with CKD. These include an early and progressive rise in fibroblast growth factor 23 (FGF 23), followed by an increase in parathyroid hormone (PTH) with a decrease in 1,25-dihydroxyvitamin D (1,25 Vit D). Over the last 20 years, a large number of studies have shown that hyperphosphatemia is a strong predictor of adverse clinical outcomes including increased incidence of vascular calcification, cardiovascul...
Source: Seminars in Dialysis - April 19, 2018 Category: Urology & Nephrology Authors: Dhillon-Jhattu S, Sprague SM Tags: Semin Dial Source Type: research

Hemodialysis: A model for extreme physiology in a vulnerable patient population.
Abstract Hemodialysis (HD) is a lifesaving treatment for patients with end-stage renal disease, which is very efficient in the correction of abnormalities of the internal environment. However, this efficiency also induces significant hemodynamic, thermal, and respiratory stressors. These have parallels with the extreme physiologic demands which are normally mainly experienced by healthy subjects under adverse environmental conditions, with the difference that they must be endured by a vulnerable patient population. Hemodynamic stress induced by ultrafiltration leads to a decline in circulating blood volume, which ...
Source: Seminars in Dialysis - April 19, 2018 Category: Urology & Nephrology Authors: Kooman JP, Katzarski K, van der Sande FM, Leunissen KM, Kotanko P Tags: Semin Dial Source Type: research

Does peritoneal dialysis have a role in urgent-start end-stage kidney disease?
This article is intended to equip the reader with a practical sense of whether an urgent-start PD program would be appropriate in his or her own clinical context and if appropriate, what factors would be necessary for such a program to flourish. As such, we summarize latent factors, which are necessary to consider before instituting an urgent-start PD. Then, using a series of clinical vignettes, highlight the component parts of a successful urgent-start PD program and the patient population who stand to benefit most from this strategy. The discussion is then balanced by presenting limitations to consider in the urgent-star...
Source: Seminars in Dialysis - April 19, 2018 Category: Urology & Nephrology Authors: McQuillan RF, Lok CE Tags: Semin Dial Source Type: research

Should phosphate management be limited to the KDIGO/ KDOQI guidelines?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 19, 2018 Category: Hematology Authors: Sangeet Dhillon ‐Jhattu , Stuart M. Sprague Source Type: research

Clinical problems in hemodialysis patients with autosomal dominant polycystic kidney disease.
Abstract Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney. Due to its genetic pattern, the disease differs from other CKD. ADPKD is a multi-system, progressive disorder which is frequently complicated with hypertension, cardiovascular events and cerebrovascular disease. Thus, there are many clinical problems specific to ADPKD. In this article, we reviewed these clinical problems and their management in ADPKD with hemodialysis patients. PMID: 29664556 [PubMed - as supplied by publisher] (Source: Seminars in Dialysis)
Source: Seminars in Dialysis - April 17, 2018 Category: Urology & Nephrology Authors: Kocyigit I, Eroglu E, Gungor O Tags: Semin Dial Source Type: research

Clinical problems in hemodialysis patients with autosomal dominant polycystic kidney disease
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 17, 2018 Category: Hematology Authors: Ismail Kocyigit , Eray Eroglu , Ozkan Gungor Source Type: research

Is the management of diabetes different in dialysis patients?
Abstract Diabetes is highly and increasingly prevalent in the dialysis population and negatively impacts both quality and quantity of life. Nevertheless, the best approach to these patients is still debatable. The question of whether the management of diabetes should be different in dialysis patients does not have a clear yes or no answer but is divided into too many sub-issues that should be carefully considered. In this review, lifestyle, cardiovascular risk, and hyperglycemia management are explored, emphasizing the possible pros and cons of a similar approach to diabetes in dialysis patients compared to the ge...
Source: Seminars in Dialysis - April 16, 2018 Category: Urology & Nephrology Authors: Coelho S Tags: Semin Dial Source Type: research

Is the management of diabetes different in dialysis patients?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 16, 2018 Category: Hematology Authors: Silvia Coelho Source Type: research

An aspirational diet for dialysis patients: Evidence and theory.
Abstract Dialytic renal replacement therapy is now entering into its sixth decade in the United States. Despite major advances in dialysis technology, regimens and protocols, and pharmacological treatments, patients' restricted dietary intake remains the lynchpin to their well-being and success. Herein, we review current guidelines that limit dietary intake of nutrients and minerals in dialysis patients and explore potential ways to use them in designing a daily food intake that is not only healthy, but also easy to implement and therefore patient friendly. The main theme behind this review is attempting to emphas...
Source: Seminars in Dialysis - April 13, 2018 Category: Urology & Nephrology Authors: Uribarri J Tags: Semin Dial Source Type: research

An aspirational diet for dialysis patients: Evidence and theory
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 13, 2018 Category: Hematology Authors: Jaime Uribarri Source Type: research

Breaking the cycle of functional decline in older dialysis patients
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 11, 2018 Category: Hematology Authors: Rasheeda K. Hall , Mara A. McAdams ‐DeMarco Source Type: research

Breaking the cycle of functional decline in older dialysis patients.
Abstract Currently, older adults comprise nearly one-third of prevalent US dialysis patients, and this proportion will increase as the population ages. Older dialysis patients experience greater morbidity and mortality than nondialysis patients of the same age, and in part, it is related to progressive functional decline. Progressive functional decline, characterized by need for assistance with more than 2 activities of daily living, contributes to risk of hospitalization, further functional decline, and subsequent nursing home placement when a patient no longer functions independently at home. Progressive functio...
Source: Seminars in Dialysis - April 11, 2018 Category: Urology & Nephrology Authors: Hall RK, McAdams-DeMarco MA Tags: Semin Dial Source Type: research

Haste makes waste —Should current guideline recommendations for initiation of renal replacement therapy for acute kidney injury be changed?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 10, 2018 Category: Hematology Authors: Jill Vanmassenhove , Raymond Vanholder , Wim Van Biesen , Norbert Lameire Source Type: research

Haste makes waste-Should current guideline recommendations for initiation of renal replacement therapy for acute kidney injury be changed?
Abstract There is broad consensus among guideline organizations that renal replacement therapy (RRT) should not be delayed in case of life-threatening conditions. However, in case of severe acute kidney injury (AKI) without these conditions, it is unclear whether immediate RRT has an advantage over delayed RRT. Two recently published randomized controlled trials (AKIKI and ELAIN) with seemingly opposite results have reignited the discussion whether guideline recommendations on initiation strategies in severe AKI should be adapted. This editorial discusses RRT initiation strategies in severe AKI, based on recent li...
Source: Seminars in Dialysis - April 10, 2018 Category: Urology & Nephrology Authors: Vanmassenhove J, Vanholder R, Van Biesen W, Lameire N Tags: Semin Dial Source Type: research

Hemodialysis-induced cardiovascular disease.
Abstract More than half of all deaths among end stage renal disease (ESRD) patients are due to cardiovascular disease (CVD). Cardiovascular changes secondary to renal dysfunction, including fluid overload, uremic cardiomyopathy, secondary hyperparathyroidism, anemia, altered lipid metabolism, and accumulation of gut microbiota-derived uremic toxins like trimethylamine N-oxidase, contribute to the high risk for CVD in the ESRD population. In addition, conventional hemodialysis (HD) itself poses myocardial stress and injury on the already compromised cardiovascular system in uremic patients. This review will provide...
Source: Seminars in Dialysis - April 6, 2018 Category: Urology & Nephrology Authors: Ahmadmehrabi S, Tang WHW Tags: Semin Dial Source Type: research

Hemodialysis ‐induced cardiovascular disease
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - April 6, 2018 Category: Hematology Authors: Shadi Ahmadmehrabi , W. H. Wilson Tang Source Type: research

Should we look beyond Kt/V urea in assessing dialysis adequacy?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 23, 2018 Category: Hematology Source Type: research

Should we look beyond Kt/V urea in assessing dialysis adequacy?
Abstract Since the advent of maintenance dialysis therapy, our interpretation of what adequate dialysis really is has broadened and become more controversial. This is not only due to our changing and aging dialysis population but also to our evolving knowledge base. As nephrologists, we strive to achieve both quality and (often) quantity of life for our patients and we feel reassured when we have a quantifiable marker to show for our efforts. However, we suggest that adequate dialysis reaches far beyond the realms of attaining a particular biochemical result. Dialysis adequacy should encompass a more comprehensive...
Source: Seminars in Dialysis - March 23, 2018 Category: Urology & Nephrology Authors: Jones CB, Bargman JM Tags: Semin Dial Source Type: research

---
Seminars in Dialysis, Ahead of Print. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 23, 2018 Category: Hematology Source Type: research

Dialysis modality and survival: Done to death
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 14, 2018 Category: Hematology Source Type: research

---
Seminars in Dialysis, Ahead of Print. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 14, 2018 Category: Hematology Source Type: research

Dialysis modality and survival: Done to death.
Abstract The debate surrounding whether peritoneal dialysis or hemodialysis is associated with differential survival continues as the numerous comparative studies over the past 3 decades have yielded conflicting results. Findings have also evolved over time in the setting of changing patient characteristics, advances in dialytic technologies, and the use of more robust statistical and epidemiologic approaches. Here, we will critically review the body of evidence, both historical and contemporary, comparing survival across dialysis modalities. Significant limitations of the observational nature of the current liter...
Source: Seminars in Dialysis - March 14, 2018 Category: Urology & Nephrology Authors: Trinh E, Chan CT, Perl J Tags: Semin Dial Source Type: research

When is more frequent hemodialysis beneficial?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 12, 2018 Category: Hematology Source Type: research

---
Seminars in Dialysis, Ahead of Print. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 12, 2018 Category: Hematology Source Type: research

When is more frequent hemodialysis beneficial?
Abstract The use of frequent hemodialysis (HD) is growing, with the hope of improving outcomes in end-stage renal disease. We narratively review the three randomized trials, 15 comparative cohort studies, and several case series of frequent HD that empirically demonstrate the potential efficacy and adverse effects of these regimens. Taken together, the randomized studies suggest frequent HD may result in left ventricular mass regression. This effect is most pronounced when left ventricular mass is abnormal, but attenuated by significant residual urine output. Both frequent short and long HD consistently improved b...
Source: Seminars in Dialysis - March 12, 2018 Category: Urology & Nephrology Authors: Suri RS, Kliger AS Tags: Semin Dial Source Type: research

Abdominal visceral perforation by buried peritoneal dialysis catheters: Cause or coincidence?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 7, 2018 Category: Hematology Source Type: research

Do arteriovenous fistulas increase cardiac risk?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 7, 2018 Category: Hematology Source Type: research

Does inflammation affect outcomes in dialysis patients?
Seminars in Dialysis, EarlyView. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 7, 2018 Category: Hematology Source Type: research

---
Seminars in Dialysis, Ahead of Print. (Source: Seminars In Dialysis)
Source: Seminars In Dialysis - March 7, 2018 Category: Hematology Source Type: research