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IJERPH, Vol. 20, Pages 1756: Encouraging and Reinforcing Safe Breastfeeding Practices during the COVID-19 Pandemic
Conclusion: The mothers were not more knowledgeable regarding breastfeeding safely one year into the COVID-19 pandemic. Conflicting lay information can create healthy behavior ambivalence, which can be prevented by health professionals confidently advising mothers to wear face masks when breastfeeding, restricting visitors and outings, and accepting COVID-19 vaccination. This pandemic remains an open opportunity to promote and encourage breastfeeding to every mother as the default newborn feeding method.
Source: International Journal of Environmental Research and Public Health - January 18, 2023 Category: Environmental Health Authors: Flora Ukoli Jacinta Leavell Amasyah Mayo Jayla Moore Nia Nchami Allysceaeioun Britt Tags: Article Source Type: research
ACOG Committee Opinion No. 756: Optimizing Support for Breastfeeding as Part of Obstetric Practice.
Authors:
Abstract
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, inte...
Source: Obstetrics and Gynecology - September 25, 2018 Category: OBGYN Tags: Obstet Gynecol Source Type: research
ACOG Committee Opinion No. 756 Summary: Optimizing Support for Breastfeeding as Part of Obstetric Practice.
Authors:
Abstract
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, inte...
Source: Obstetrics and Gynecology - September 25, 2018 Category: OBGYN Tags: Obstet Gynecol Source Type: research
Detection and verification of 2.3 million cancer mutations in NCI60 cancer cell lines with a cloud search engine.
We present and examine the abilities of Bolt, a new cloud-based proteomics search engine to search for the presence of over 2.3 million known cancer mutations in a matter of minutes while still performing a standard proteomics search that includes 31 post translational modifications. We use previously published proteomics data sets and identify mutations that are verified using genomic studies as well as previous proteomics efforts. Our results also emphasize the need to search for mutations in a comprehensive manner while still searching for both common and rare PTMs. SIGNIFICANCE: We present and examine the abilities of ...
Source: Journal of Proteomics - August 20, 2019 Category: Biochemistry Authors: Prakash A, Majumder S, Ahmad S, Varkey M, Anish TA, Jenkins C, Rigby M, Orsburn B Tags: J Proteomics Source Type: research
Adoptive T-cell Transfer Therapy and Oncogene-Targeted Therapy for Melanoma: The Search for Synergy.
Abstract
The clinical strengths of immunotherapy and small-molecule inhibitors targeting the mitogen-activated protein kinase (MAPK) pathway appear to be largely complementary for the treatment of advanced melanoma. In current practice, most patients with BRAF V600 mutant melanomas will see both modalities. Several in vitro and in vivo studies suggest that combining immunotherapy with MAPK inhibition may have synergistic effects. First, mouse models show that adoptive cell therapy (ACT) can be enhanced by vaccination. Rapid tumor destruction by vemurafenib could provide a vaccine-like stimulus to adoptively transf...
Source: Clinical Cancer Research - October 1, 2013 Category: Cancer & Oncology Authors: Kwong ML, Neyns B, Yang JC Tags: Clin Cancer Res Source Type: research
Abstract IA07: In search of racial disparities in HPV vaccination
Background: Racial disparities in cervical cancer deaths are longstanding, with African American and Latina women more likely to die from the disease. The advent of HPV vaccine created an opportunity to reduce or end these disparities, but only if uptake was either uniformly high across all females or higher among minority than non-minority females. Thus, interest in racial disparities in HPV vaccine coverage has been understandably high.Findings: Data from several sources show racial disparities and "reverse disparities" in HPV vaccination coverage. First, the most reliable national data are from the National Immunization...
Source: Cancer Epidemiology Biomarkers and Prevention - September 30, 2015 Category: Cancer & Oncology Authors: Brewer, N. T., Moss, J. L., Reiter, P. L. Tags: Vaccines and Immunoprevention: Oral Presentations - Invited Abstracts Source Type: research
Cancers, Vol. 10, Pages 492: Recent Advances in Oncolytic Virotherapy and Immunotherapy for Glioblastoma: A Glimmer of Hope in the Search for an Effective Therapy?
nin
To date, no targeted drugs, antibodies or combinations of chemotherapeutics have been demonstrated to be more efficient than temozolomide, or to increase efficacy of standard therapy (surgery, radiotherapy, temozolomide, steroid dexamethasone). According to recent phase III trials, standard therapy may ensure a median overall survival of up to 18–20 months for adult patients with newly diagnosed glioblastoma. These data explain a failure of positive non-controlled phase II trials to predict positive phase III trials and should result in revision of the landmark Stupp trial as a historical control for ...
Source: Cancers - December 5, 2018 Category: Cancer & Oncology Authors: Aleksei A. Stepanenko Vladimir P. Chekhonin Tags: Review Source Type: research
Cancers, Vol. 14, Pages 4191: Cancerous Tumor Controlled Treatment Using Search Heuristic (GA)-Based Sliding Mode and Synergetic Controller
ad Fazal Ijaz
Cancerous tumor cells divide uncontrollably, which results in either tumor or harm to the immune system of the body. Due to the destructive effects of chemotherapy, optimal medications are needed. Therefore, possible treatment methods should be controlled to maintain the constant/continuous dose for affecting the spreading of cancerous tumor cells. Rapid growth of cells is classified into primary and secondary types. In giving a proper response, the immune system plays an important role. This is considered a natural process while fighting against tumors. In recent days, achieving a better method to treat ...
Source: Cancers - August 29, 2022 Category: Cancer & Oncology Authors: Fazal Subhan Muhammad Adnan Aziz Inam Ullah Khan Muhammad Fayaz Marcin Wozniak Jana Shafi Muhammad Fazal Ijaz Tags: Article Source Type: research
Mother ’s Milk and the Environment: Might Chemical Exposures Impair Lactation?
New mothers who quit breastfeeding earlier than they had wanted often chalk it up to not being able to produce enough milk. But a handful of researchers are exploring whether certain environmental exposures may affect some women’s ability to lactate.© Tony Anderson/Getty Images
Lactation support includes teaching women techniques to breastfeed and build their milk supply, as well as reassuring them of their ability to nourish their infants.© Phanie/Alamy Stock Photo
Education and counseling have been important tools in boosting breastfeeding rates, after decades of marketing mess...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: News Focus January 2017 Source Type: research
Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis
Conclusion
Recent advances in research on HTLV-1 provide better understanding of the molecular pathogenesis and mechanisms of HAM/TSP, and several clinical trials of novel therapies for patients with HAM/TSP have been initiated. However, long-term improvement of motor disability and quality of life still have not been achieved in HAM/TSP patients, and the clinical management remains challenging. Given that HAM/TSP is characterized by activated T-cells in both the periphery and CNS, studies in HAM/TSP will be highly informative for clarifying the pathogenesis of other neuroinflammatory disorders such as multiple sclerosis....
Source: Frontiers in Microbiology - April 23, 2019 Category: Microbiology Source Type: research
The Effectiveness of Disaster Risk Communication: A Systematic Review of Intervention Studies
The objectives of the interventions were to improve the health knowledge and behaviour in relation to disasters, and to decrease the incidence of negative health events. The studies were chosen on that basis, and several studies reported additional outcomes that were outside the scope of this review. The knowledge, behaviour and incidence outcomes are described in detail in Appendix 3 (characteristics and results of included studies).
Results of Individual Studies
1 Effect of Risk Communication Interventions to Promote Disaster Mitigation and Preparedness
1.1 Communication to Promote Mitigation and Preparedness for Infec...
Source: PLOS Currents Disasters - August 22, 2014 Category: Global & Universal Authors: dtbradley Source Type: research
Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant < em > Staphylococcus aureus < /em > USA300 for the Identification of Potential Therapeutic Targets: An In-Silico Approach
In this study, staphylococcal FemA protein (P0A0A5) is subjected to structure-based virtual screening for the drug repurposing approach. There are 20 residues missing in the crystal structure of FemA, and 12 of these residues are located at the catalytic site. The missing residues are modelled, and stereochemistry is checked. FDA approved drugs available in the DrugBank database have been used in virtual screening with FemA in search of potential repurposed molecules. This approach provides us with 10 drugs that may be used in the treatment of methicillin-resistant staphylococcal mediated diseases. AutoDock 4.2 is used for...
Source: Cell Research - September 22, 2021 Category: Cytology Authors: Shakilur Rahman Amit Kumar Das Source Type: research
A systematic review and meta-analysis of immune response against first and second doses of SARS-CoV-2 vaccines in adult patients with hematological malignancies
CONCLUSION: Our findings highlight the substantially low rate of seroprotection in patients with hematological malignancies with a wide range of rates among disease subgroups and different treatments; further highlighting the fact that booster doses might be acquired for these patients to improve immunity against SARS-CoV-2.PMID:35843148 | PMC:PMC9273573 | DOI:10.1016/j.intimp.2022.109046
Source: International Immunopharmacology - July 17, 2022 Category: Allergy & Immunology Authors: Maryam Noori Shadi Azizi Farhan Abbasi Varaki Seyed Aria Nejadghaderi Davood Bashash Source Type: research
Bad news: The influence of news coverage and Google searches on Gardasil adverse event reporting.
CONCLUSION: The results suggest that some of the adverse events reported were not related to the vaccination itself, but to news coverage and internet search volumes, which may have contributed to public concerns about potentially unpleasant or harmful outcomes. These findings have implications for the importance of psychological and social factors in adverse event reporting, and the role of the news media in disseminating health information.
PMID: 29128382 [PubMed - as supplied by publisher]
Source: Vaccine - November 8, 2017 Category: Allergy & Immunology Authors: Faasse K, Porsius JT, Faasse J, Martin LR Tags: Vaccine Source Type: research
The prevalence of COVID-19 vaccination and vaccine hesitancy in pregnant women: an internet-based cross-sectional study in Japan
CONCLUSIONS: COVID-19 vaccination is not widespread among pregnant women in Japan although many vaccines have been shown to be safe in pregnancy. Accurate information dissemination and boosting trust in the government may be important to address vaccine hesitancy among pregnant women.PMID:35095091 | DOI:10.2188/jea.JE20210458
Source: Cancer Control - January 31, 2022 Category: Cancer & Oncology Authors: Yoshihiko Hosokawa Sumiyo Okawa Ai Hori Naho Morisaki Yoko Takahashi Takeo Fujiwara Shoji F Nakayama Hiromi Hamada Toyomi Satoh Takahiro Tabuchi Source Type: research
