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Vaccination: Meningitis Vaccine

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Total 126 results found since Jan 2013.

Interpretation of Post-Pneumococcal Vaccine Antibody Levels: Concerns and Pitfalls
Publication date: Available online 27 December 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Caitlin MG. McNulty, James T. Li
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 28, 2018 Category: Allergy & Immunology Source Type: research

CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.
This study aims to determine the immunogenicity of CbpM, CbpG and CbpL proteins of Streptococcus pneumoniae in a mice model. The genes were cloned into pET21a expression vector and the recombinant proteins were produced. Mice were immunized with the purified recombinant proteins. Subsequently, the mice were challenged with S. pneumoniae ATCC 49619 (2×106 CFU) and their survival and bacterial clearances were followed 24 hours after infection. The antibody responses of the mice were determined by ELISA assay. The opsonophagocytosis assay was performed using rabbit's sera. Passive immunization was carried out using two doses...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 3, 2018 Category: Allergy & Immunology Authors: Kazemian H, Afshar D, Garcia E, Pourmand MR, Jeddi-Tehrani M, Aminharati F, Shokri F, Yazdi MH Tags: Iran J Allergy Asthma Immunol Source Type: research

Interlaboratory variability in multiplexed pneumococcal antibody testing
Assays that measure levels of IgG antibodies against specific serotypes of Streptococcus pneumoniae were initially developed and subsequently refined primarily for evaluation of vaccine efficacy.1 Because polysaccharide vaccines represent a well-defined immunogenic stimulus, measurement of serotype-specific antibody production in response to vaccination with the pneumococcal polysaccharide vaccine (PPV23) has also been used to evaluate humoral immune function in cases of suspected primary immune deficiency disease (PIDD).
Source: Journal of Allergy and Clinical Immunology - November 20, 2018 Category: Allergy & Immunology Authors: David C. LaFon, Moon H. Nahm Tags: Letter to the Editor Source Type: research

A new diagnosis of cvid in a pediatric patient presenting with streptococcus pneumoniae meningitis
Common Variable Immune Deficiency (CVID) can present with a range of organ system involvement, including normal number of B-cells but decreased IgG, eventual decline in IgA and/or IgM, and poor/absent response to vaccinations.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2018 Category: Allergy & Immunology Authors: K. Schissler, C. Ortega, V. Hernandez-Trujillo, J. Calderon Tags: M273 Source Type: research

Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort
ConclusionThis study highlights similarities and differences in clinical and genetic spectrum of the most common PAD-associated gene defects. This comprehensive comparison will facilitate clinical decision making, and improve prognosis and targeted treatment.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Late presentation of subtotal C6 deficiency in a patient with recurrent Neisseria meningitides infections
The complement system is important in fighting meningococcal disease. Recurrent meningococcal infections are a significant feature of terminal complement deficiency.1 The terminal complement system produces a membrane attack complex (MAC), which creates pores in bacteria, leading to lysis of microorganisms. Most invasive meningococcal infections are caused by Neisseria serotypes A, B, C, W-135, and Y, all of which are targeted with commercially available vaccines. Infections with less common serotypes are seen in patients with terminal complement deficiencies.
Source: Annals of Allergy, Asthma and Immunology - April 1, 2018 Category: Allergy & Immunology Authors: Lana Rosenfield, Anna Cvetkovic, Kevin Woodward, Jaclyn Quirt Source Type: research

Transcutaneous immunization with pneumococcal surface protein A in mice
ConclusionThese results show that TCI with PspA plus CT induces antigen‐specific mucosal and systemic immune responses. This suggests that this method is an effective mucosal immunization strategy for induction of protective pneumococcal‐specific Ab responses in blockade of S. pneumoniae colonization of the nasal cavity. Level of EvidenceNA. Laryngoscope, 2017
Source: The Laryngoscope - December 11, 2017 Category: ENT & OMF Authors: Hiromi Nagano, Masaki Kawabata, Gen Sugita, Akitoshi Tsuruhara, Junichiro Ohori, Tomohiro Jimura, Keiichi Miyashita, Yuichi Kurono, Kazuhiro Tomonaga, David E. Briles, Kohtaro Fujihashi Tags: Allergy/Rhinology Source Type: research

P041 Successful administration of MenB-4C vaccine in the setting of an adverse reaction to MenB-FHbp
Two serogroup B meningococcal (MenB) vaccines, MenB-FHbp and MenB-4C, are available for use in persons aged 10-25 years in the United States. The Advisory Committee on Immunization Practices (ACIP) recommends either three-dose series of MenB-FHbp or two-dose series of MenB-4C. Adverse reactions like anaphylaxis have been infrequently reported.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: R. Kuriakose, C. Patel, B. Kaplan Source Type: research

OR093 Evaluating pneumococcal vaccination status, patient demographics and disease burden at an Internal Medicine clinic
Pneumococcal illnesses are the cause of most frequently preventable diseases. A large number of patients are admitted for community acquired pneumonia (CAP) every month leading to prolonged hospitalizations and mortality. In this project, the relationship between pneumococcal vaccination status, patient demographics and their disease status was explored.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: P. Sandhu, R. D'Mello, E. Abou-Jaoude Source Type: research

P283 Pneumococcal osteomyelitis: a rare diagnosis suggestive of immune deficiency
Despite routine immunization with pneumococcal conjugate vaccines, Streptococcus pneumoniae is still a significant cause of bacteremia, pneumonia and meningitis. Osteoarticular pneumococcal infections are very rare, accounting for less than 5% of all invasive pneumococcal diseases (IPD).
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: T. Peng, M. Garcia-Lloret Source Type: research

P379 Getting with the guidelines: a primary care approach to improving pneumococcal vaccine administration
Streptococcal pneumonia is the most common cause of pneumonia and the leading agent causing hospitalization from bacteremia in adults. Vaccines containing the antigens of these surface polysaccharides are the primary means by which providers attempt to prevent or minimize the severity of streptococcal infections. Pneumonia remains a significant burden in the United making it important that we are aware of our current rate of appropriate vaccine administration.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: R. D'Mello, P. Sandhu Source Type: research

Pneumococcal Vaccine for Only Half With Work - Related Asthma
54 percent of adults with work - related asthma, 35 percent with non - work - related asthma vaccinated
Source: Pulmonary Medicine News - Doctors Lounge - September 28, 2017 Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Allergy, Nursing, Pathology, Pharmacy, Pulmonology, Journal, Source Type: news

Erratum
In the article entitled “A case of atypical, complete DiGeorge syndrome without 22q11 mutation” (Ann Allergy Asthma Immunol 2017;118:629-647), the following sentence is incorrect: “Tetanus and pneumococcal immunoglobulin G titers were non-protective; the patient was not yet unvaccinated.” The sentence should read, “Tetanus and pneumococcal immunoglobulin G titers were non-protective; the patient was not yet vaccinated.”
Source: Annals of Allergy, Asthma and Immunology - June 28, 2017 Category: Allergy & Immunology Tags: Erratum Source Type: research

A case series evaluating the serological response of adult asthma patients to the 23-valent pneumococcal polysaccharide vaccine
Asthma is an independent risk factor for invasive pneumococcal disease; however, the immune response of adult asthma patients to pneumococcal vaccination is unknown. We explore the serologic response of patien...
Source: Allergy, Asthma and Clinical Immunology - June 7, 2017 Category: Allergy & Immunology Authors: C. R. Laratta, K. Williams, D. Vethanayagam, M. Ulanova and H. Vliagoftis Source Type: research