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The World Is Not Ready for the Next Pandemic
Across China, the virus that could spark the next pandemic is already circulating. It’s a bird flu called H7N9, and true to its name, it mostly infects poultry. Lately, however, it’s started jumping from chickens to humans more readily–bad news, because the virus is a killer. During a recent spike, 88% of people infected got pneumonia, three-quarters ended up in intensive care with severe respiratory problems, and 41% died. What H7N9 can’t do–yet–is spread easily from person to person, but experts know that could change. The longer the virus spends in humans, the better the chance that i...
Source: TIME.com: Top Science and Health Stories - May 4, 2017 Category: Consumer Health News Authors: Bryan Walsh Tags: Uncategorized CDC Disease ebola Gates Foundation MERS outbreak pandemic Zika Source Type: news

UK parents attitudes towards meningococcal group B (MenB) vaccination: a qualitative analysis
Conclusions The successful implementation of the MenB vaccination programme depends on its acceptance by parents. In view of parents’ recognition of the severity of meningitis and septicaemia, and successful introduction of other vaccines to prevent bacterial meningitis and septicaemia, the MenB vaccination programme is likely to be successful. However, the need for additional injections, the likelihood of post-immunisation fever and its management are issues about which parents will need information and reassurance from healthcare professionals. Public Health England has developed written information for parents, in...
Source: BMJ Open - May 4, 2017 Category: Journals (General) Authors: Jackson, C., Yarwood, J., Saliba, V., Bedford, H. Tags: Open access, Immunology (including allergy) Research Source Type: research

Updated ACIP Recommendations Nix LAIV, Expand HBV Vaccination Updated ACIP Recommendations Nix LAIV, Expand HBV Vaccination
Final vaccination recommendations for adults advise against the use of LAIV, outline allergy precautions, expand HBV vaccination, and clarify schedules for HPV prevention and meningococcal disease.Medscape Medical News
Source: Medscape Allergy Headlines - February 6, 2017 Category: Allergy & Immunology Tags: Internal Medicine News Alert Source Type: news

The Clinical Significance of Specific Antibody Deficiency (SAD) Severity in Chronic Rhinosinusitis (CRS)
Conclusions This study provides real world data supporting stratification of SAD by severity, demonstrating a significant increase in the comorbid severity of asthma and infections in CRS patients with moderate-to-severe SAD compared with those with mild SAD and those without SAD.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 26, 2017 Category: Allergy & Immunology Source Type: research

Invasive meningococcal disease in children in Ireland, 2001-2011
Conclusions Despite the meningococcal C vaccination campaign, invasive meningococcal disease continues to cause serious morbidity and claim lives. Group B infections remain dominant. As children who die often present with fulminant disease, preventive strategies including use of meningococcal B vaccine are needed to avert death and sequelae.
Source: Archives of Disease in Childhood - November 17, 2016 Category: Pediatrics Authors: O Maoldomhnaigh, C., Drew, R. J., Gavin, P., Cafferkey, M., Butler, K. M. Tags: Epidemiologic studies, Immunology (including allergy), Drugs: infectious diseases, Vaccination / immunisation Original article Source Type: research

4th Pediatric Allergy and Asthma Meeting (PAAM)
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut mic...
Source: Clinical and Translational Allergy - October 31, 2016 Category: Allergy & Immunology Source Type: research

Infections Nearly Halved After Meningococcal Vaccine Intro in UK Infections Nearly Halved After Meningococcal Vaccine Intro in UK
Infant immunization with the Bexsero vaccine led to a 42% decrease in the number of cases of meningococcal B meningitis and septicemia in the first year.Medscape Medical News
Source: Medscape Allergy Headlines - September 12, 2016 Category: Allergy & Immunology Tags: Pediatrics News Source Type: news

Symptomatic Primary Selective Immunoglobulin M Deficiency with Nonprotective Pneumococcal Titers Responsive to Subcutaneous Immunoglobulin Treatment
We report on an adult who presented with symptomatic SIgMD with impaired pneumococcal polysaccharide antibody responses and lymphopenia, who experienced a significant clinical improvement in the frequency of infections after subcutaneous immunoglobulin replacement therapy.Int Arch Allergy Immunol 2016;170:138-140
Source: International Archives of Allergy and Immunology - August 9, 2016 Category: Allergy & Immunology Source Type: research

The First World War years of Sydney Domville Rowland: an early case of possible laboratory-acquired meningococcal disease
Sydney Domville Rowland was a bacteriologist and staff member at the Lister Institute of Preventive Medicine when the First World War broke out in 1914. Following a request to the Director of the Lister Institute to staff and equip a mobile field laboratory as quickly as possible, Rowland was appointed to take charge of No. 1 Mobile Laboratory and took up a temporary commission at the rank of Lieutenant in the Royal Army Medical Corps. On 9 October 1914, Rowland set out for the European mainland and was subsequently attached to General Headquarters in Saint-Omer, France (October 1914-June 1915), No. 10 Casualty Clearing St...
Source: Journal of the Royal Army Medical Corps - July 28, 2016 Category: Journals (General) Authors: Wever, P. C., Hodges, A. J. Tags: Infectious diseases, Immunology (including allergy), Drugs: CNS (not psychiatric), Infection (neurology), Trauma, Injury, Health promotion Footnotes and endpieces Source Type: research

Who to Vax: A free online tool to identify adults for pneumococcal vaccination.
PMID: 27346566 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - June 22, 2016 Category: Allergy & Immunology Authors: Stone CA, Hartert TV Tags: Ann Allergy Asthma Immunol Source Type: research

Selective Subnormal IgG1 in 54 Adult Index Patients with Frequent or Severe Bacterial Respiratory Tract Infections.
Authors: Barton JC, Bertoli LF, Barton JC, Acton RT Abstract We characterized 54 adult index patients with reports of frequent or severe bacterial respiratory tract infections at diagnosis of selective subnormal IgG1. Mean age was 50 ± 13 (SD) y; 87.0% were women. Associated disorders included the following: autoimmune conditions 50.0%; hypothyroidism 24.1%; atopy 38.9%; and other allergy 31.5%. In 35.5%, proportions of protective S. pneumoniae serotype-specific IgG levels did not increase after polyvalent pneumococcal polysaccharide vaccination (PPPV). Blood lymphocyte subset levels were within reference limits i...
Source: Journal of Immunology Research - April 30, 2016 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Evaluation of the immunogenicity of the 13-valent conjugated pneumococcal vaccine in rheumatoid arthritis patients treated with etanercept
Conclusions In RA patients treated with ETA, vaccination with PCV13 is effective and safe, resulting in pAR one and two months after vaccination. Higher age at vaccination was identified as predictors of impaired pAR. The efficacy of vaccination may be more pronounced in younger RA patients. The vaccine is safe in RA patients on ETA.
Source: Joint Bone Spine - March 17, 2016 Category: Orthopaedics Source Type: research

The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis
Conclusions Among patients starting tofacitinib, diminished responsiveness to PPSV-23, but not influenza, was observed, particularly in those taking concomitant methotrexate. Among existing tofacitinib users, temporary drug discontinuation had limited effect upon influenza or PPSV-23 vaccine responses. Trial registration numbers NCT01359150, NCT00413699.
Source: Annals of the Rheumatic Diseases - March 10, 2016 Category: Rheumatology Authors: Winthrop, K. L., Silverfield, J., Racewicz, A., Neal, J., Lee, E. B., Hrycaj, P., Gomez-Reino, J., Soma, K., Mebus, C., Wilkinson, B., Hodge, J., Fan, H., Wang, T., Bingham, C. O. Tags: Open access, Immunology (including allergy), Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis Clinical and epidemiological research Source Type: research

Anaphylaxis to pneumococcal vaccine; CRM(197): Novel cause of vaccine allergy
This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - February 4, 2016 Category: Allergy & Immunology Authors: Esozia Arroabarren, Marta Anda, Maria Luisa Sanz Tags: Letter to the Editor Source Type: research

New Vaccines in 2016 Pediatric Immunization Schedule New Vaccines in 2016 Pediatric Immunization Schedule
Recommendations for the recently licensed meningococcal B and 9-valent human papillomavirus vaccine are now in the official 2016 childhood immunization schedule Medscape Medical News
Source: Medscape Allergy Headlines - February 1, 2016 Category: Allergy & Immunology Tags: Pediatrics News Alert Source Type: news

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