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Condition: Chronic Obstructive Pulmonary

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Total 1666 results found since Jan 2013.

The gut microbiome is a significant risk factor for future chronic lung disease
This work demonstrates the link between the gut microbiome and incident respiratory diseases in a large prospective population-based cohort, suggesting the potential of the gut microbiome as a biomarker for COPD and adult-onset asthma.
Source: Journal of Allergy and Clinical Immunology - December 29, 2022 Category: Allergy & Immunology Authors: Yang Liu, Shu Mei Teo, Guillaume Meric, Howard H.F. Tang, Qiyun Zhu, Jon G. Sanders, Yoshiki Vazquez-Baeza, Karin Verspoor, Ville A. Vartiainen, Pekka Jousilahti, Leo Lahti, Teemu Niiranen, Aki S. Havulinna, Rob Knight, Veikko Salomaa, Michael Inouye Source Type: research

The Difference in All-Cause Mortality Between Allergic Bronchopulmonary Aspergillosis with and without Chronic Obstructive Pulmonary Disease
Source: Journal of Asthma and Allergy - December 28, 2022 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Asthma chronic obstructive pulmonary disease and lower respiratory disorders
Ann Allergy Asthma Immunol. 2022 Oct 6:S1081-1206(22)01727-6. doi: 10.1016/j.anai.2022.09.015. Online ahead of print.NO ABSTRACTPMID:36464594 | DOI:10.1016/j.anai.2022.09.015
Source: Annals of Allergy, Asthma and Immunology - December 4, 2022 Category: Allergy & Immunology Authors: James T Li Source Type: research

Recent miRNA Research in Asthma
AbstractPurpose of ReviewThe study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have been shown to be important in asthma, influencing various biological mechanisms which lead to asthma pathology and symptoms. In addition, miRNAs have been proposed as biomarkers of asthma affection status, asthma severity, and asthma treatment response. We review all recent asthma-miRNA work, while also presenting comprehensive tables of all miRNA results related to asthma.Recent FindingsWe here reviewed 63 recent studies published reporting asthma and miRNA research,...
Source: Current Allergy and Asthma Reports - December 2, 2022 Category: Allergy & Immunology Source Type: research

Differential responses of COPD macrophages to respiratory bacterial pathogens
Conclusion: Differential cytokine responses of macrophages to these bacterial species can explain neutrophilic airway inflammation associated with H.influenzae, but not S.pneumoniae in COPD. Delayed macrophage apoptosis may cause inability to clear H.influenzae.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Lea, S., Beech, A., Baker, J., Gaskell, R., Pindolia, D., Baba Dikwa, A., Shah, R., Singh, D. Tags: 05.03 - Allergy and immunology Source Type: research

Inflammatory phenotypes and comorbidities in mild-to-moderate COPD
Conclusion: Comorbidities among patients with mild-to-moderate COPD are associated with distinct inflammatory phenotypes. This confirms that the association between comorbidities and systemic inflammation in COPD is more complex than assumed until now.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Soumagne, T., Hue, S., Dalphin, J., Degano, B. Tags: 05.03 - Allergy and immunology Source Type: research

Bronchodilator reversibility in patients with severe asthma included in the GAN registry.
Conclusion: The majority of patients had negative BDR test and this was associated with lower FeNO levels and history of GERD and EGPA.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Milger-Kneidinger, K., Skowasch, D., Hamelmann, E., Mümmler, C., Idzko, M., Taube, C., Holtdirk, A., Timmerman, H., Buhl, R., Korn, S. Tags: 05.03 - Allergy and immunology Source Type: research

Nurses specialized through higher education in asthma, allergy and COPD. Experiences from a Swedish perspective - A winning concept for the clinic
Conclusion: Advanced education after bachelor’s degree has benefits both for the patient and for the society.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Stridsman, C., Zakrisson, A., Sterner, T. Tags: 09.03 - Nurses Source Type: research

Effect of exercise training on Treg cell response in severe COPD individuals: a randomized and controlled trial
Conclusion: Exercise training improves the balance between the pro- and anti-inflammatory T cell subsets and improves peripheral muscle strength and quality of life in severe COPD individuals.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Ito, J. T., Oliveira, L. M., Alves, L. V., Xavier, R. F., Sato, M. N., Carvalho, C. R. F., Tiberio, I. F. L. C., Lopes, F. D. T. Q. S. Tags: 05.03 - Allergy and immunology Source Type: research

Itepekimab significantly reduced hospitalizations or emergency department visits in former smokers with moderate-to-severe COPD
Conclusion: Itepekimab vs placebo significantly reduced hospitalizations or ED visits in former smokers with moderate-to-severe COPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Rabe, K. F., Celli, B. R., Praestgaard, A., Djandji, M., Soler, X., Abdulai, R. M., Lederer, D. J., Goulaouic, H., Nivens, M. C., Siddiqui, S., Jacob-Nara, J. A., Deniz, Y., Rowe, P. J. Tags: 05.03 - Allergy and immunology Source Type: research