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Condition: Chronic Obstructive Pulmonary

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Total 1666 results found since Jan 2013.

The Dynamic Contribution of Neutrophils in the Chronic Respiratory Diseases
Allergy Asthma Immunol Res. 2022 Jul;14(4):361-378. doi: 10.4168/aair.2022.14.4.361.ABSTRACTAsthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis are representative chronic respiratory diseases (CRDs). Although they differ in terms of disease presentation, they are all thought to arise from unresolved inflammation. Neutrophils are not only the first responders to acute inflammation, but they also help resolve the inflammation. Notably, emerging clinical studies show that CRDs are associated with systemic and local elevation of neutrophils. Moreover, murine studies suggest that airway-infiltrating...
Source: Allergy, Asthma and Immunology Research - July 15, 2022 Category: Allergy & Immunology Authors: Jongho Ham Jihyun Kim Young Gyun Ko Hye Young Kim Source Type: research

Plasma Immunoglobulin E and Risk of Exacerbation and Mortality in COPD: A Contemporary Population-Based Cohort
CONCLUSION: High plasma IgE was associated with an increased risk of severe exacerbation and all-cause mortality in individuals with COPD in the general population independent from blood eosinophils.PMID:35835293 | DOI:10.1016/j.anai.2022.06.028
Source: Annals of Allergy, Asthma and Immunology - July 14, 2022 Category: Allergy & Immunology Authors: Yunus Çolak Truls S Ingebrigtsen B ørge G Nordestgaard Jacob L Marott Peter Lange J ørgen Vestbo Shoaib Afzal Source Type: research

Chronic rhinosinusitis is associated with non –cystic fibrosis bronchiectasis: A new clinical implication?
Bronchiectasis is a rare pulmonary disease characterized by aberrant mucociliary clearance, recurrent infections, mucus production, and mucosal damage leading to permanent dilatation of bronchi.1 Several conditions may coexist with non –cystic fibrosis bronchiectasis, such as chronic obstructive pulmonary disease (COPD), recurrent pneumonia, asthma, aspirin-exacerbated respiratory disease, allergic bronchopulmonary aspergillosis, immune deficiency, primary ciliary dyskinesia, alpha 1-antitrypsin deficiency, and obstructive sleep apnea (OSA).
Source: Journal of Allergy and Clinical Immunology - July 12, 2022 Category: Allergy & Immunology Authors: Jarkko M äntylä, Paula Kauppi, Sanna Toppila-Salmi Tags: Editorial Source Type: research

Plasma Immunoglobulin E and Risk of Exacerbation and Mortality in COPD: A Contemporary Population-Based Cohort
Novel biomarkers and targeted treatments are needed for patients with chronic obstructive pulmonary disease (COPD)
Source: Annals of Allergy, Asthma and Immunology - July 11, 2022 Category: Allergy & Immunology Authors: Yunus Çolak, Truls S. Ingebrigtsen, Børge G. Nordestgaard, Jacob L. Marott, Peter Lange, Jørgen Vestbo, Shoaib Afzal Source Type: research