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Condition: Chronic Obstructive Pulmonary

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Total 1666 results found since Jan 2013.

Lung Effects of Household Air Pollution
J Allergy Clin Immunol Pract. 2022 Sep 2:S2213-2198(22)00869-8. doi: 10.1016/j.jaip.2022.08.031. Online ahead of print.ABSTRACTBiomass fuel smoke, secondhand smoke, and oxides of nitrogen are common causes of household air pollution (HAP). Almost 2.4 billion people worldwide use solid fuels for cooking and heating, mostly in low- and middle-income countries. Wood combustion for household heating is also common in many areas of high-income countries, and minorities are particularly vulnerable. HAP in low- and middle-income countries is associated with asthma, acute respiratory tract infections in adults and children, chroni...
Source: Clinical Lung Cancer - September 5, 2022 Category: Cancer & Oncology Authors: Anna Y Qiu Shuguang Leng Meredith McCormack David B Peden Akshay Sood Source Type: research

Biologics for allergic and immunologic diseases
Biologics or molecularly targeted drugs are often highly effective for the treatment of allergic diseases and other immunologic disorders, and they are relatively safe for short-term use as compared with conventional approaches such as the systemic use of corticosteroids. A  number of studies published in 2021 consistently demonstrated their effectiveness and also revealed unanticipated findings. Among them, clinical trials for asthma and chronic obstructive pulmonary disease using biologics targeting thymic stromal lymphopoietin, IL-33, and IL-33 receptor demonstrate d that these type 2 alarmin cytokines are also involve...
Source: Journal of Allergy and Clinical Immunology - September 1, 2022 Category: Allergy & Immunology Authors: Hideaki Morita, Kenji Matsumoto, Hirohisa Saito Tags: Review article Source Type: research

Review of biologics in allergy and immunology
Biologics or molecularly targeted drugs are often highly effective for the treatment of allergic diseases and other immunologic disorders, and they are relatively safe for short-term use as compared with conventional approaches such as the systemic use of corticosteroids. A  number of studies published in 2021 consistently demonstrated their effectiveness and also revealed unanticipated findings. Among them, clinical trials for asthma and chronic obstructive pulmonary disease using biologics targeting thymic stromal lymphopoietin, IL-33, and IL-33 receptor demonstrate d that these type 2 alarmin cytokines are also involve...
Source: Journal of Allergy and Clinical Immunology - September 1, 2022 Category: Allergy & Immunology Authors: Hideaki Morita, Kenji Matsumoto, Hirohisa Saito Tags: Review article Source Type: research

T helper 2 Mechanisms involved in Human Rhinovirus Infections and Asthma
Ann Allergy Asthma Immunol. 2022 Aug 21:S1081-1206(22)00695-0. doi: 10.1016/j.anai.2022.08.015. Online ahead of print.ABSTRACTHuman rhinovirus (HRV) is the most common causative agent for the common cold and its respiratory symptoms. For those with asthma, cystic fibrosis, or chronic obstructive pulmonary disease (COPD), HRVs can lead to severe and, at times, fatal complications. Furthermore, an array of innate and adaptive host immune responses leads to varying outcomes ranging from subclinical to severe. In this review, we discuss the viral pathogenesis and host immune responses associated with this virus. Specifically, ...
Source: Annals of Allergy, Asthma and Immunology - August 24, 2022 Category: Allergy & Immunology Authors: Adam S Price Joshua L Kennedy Source Type: research

T-helper 2 mechanisms involved in human rhinovirus infections and asthma
Human rhinovirus (HRV) is the most common causative agent for the common cold and its respiratory symptoms. For those with asthma, cystic fibrosis, or chronic obstructive pulmonary disease, HRVs can lead to severe and, at times, fatal complications. Furthermore, an array of innate and adaptive host immune responses leads to varying outcomes ranging from subclinical to severe. In this review, we discuss the viral pathogenesis and host immune responses associated with this virus. Specifically, we focus on the immune responses that might skew a T-helper type 2 response, including alarmins, in those with allergic asthma.
Source: Annals of Allergy, Asthma and Immunology - August 21, 2022 Category: Allergy & Immunology Authors: Adam S. Price, Joshua L. Kennedy Tags: CME Review Source Type: research

T helper 2 Mechanisms involved in Human Rhinovirus Infections and Asthma
Human rhinovirus (HRV) is the most common causative agent for the common cold and its respiratory symptoms. For those with asthma, cystic fibrosis, or chronic obstructive pulmonary disease (COPD), HRVs can lead to severe and, at times, fatal complications. Furthermore, an array of innate and adaptive host immune responses leads to varying outcomes ranging from subclinical to severe. In this review, we discuss the viral pathogenesis and host immune responses associated with this virus. Specifically, we focus upon the immune responses that might skew a Th2 response, including alarmins, in those with allergic asthma.
Source: Annals of Allergy, Asthma and Immunology - August 21, 2022 Category: Allergy & Immunology Authors: Adam S. Price, Joshua L. Kennedy Tags: CME Reviews Source Type: research

Asthma-Chronic Obstructive Pulmonary Disease: An Update
Immunol Allergy Clin North Am. 2022 Aug;42(3):xiii-xiv. doi: 10.1016/j.iac.2022.04.010. Epub 2022 Jun 30.NO ABSTRACTPMID:35965055 | DOI:10.1016/j.iac.2022.04.010
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Nicola A Hanania Louis-Philippe Boulet Source Type: research

The Physiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap
Immunol Allergy Clin North Am. 2022 Aug;42(3):575-589. doi: 10.1016/j.iac.2022.04.001. Epub 2022 Jun 30.ABSTRACTAsthma and chronic obstructive pulmonary disease (COPD) are both characterized by airway obstruction and share similar clinical manifestations. However, they differ in many respects related to underlying cause, mechanism of airway obstruction, pattern and progression of symptoms, and response to therapy. It remains unclear whether there is a unique physiologic phenotype that characterizes asthma-COPD overlap (ACO). This review describes the common and distinct physiologic tests that help define asthma and COPD an...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: David A Kaminsky Charles G Irvin Source Type: research

Asthma-Chronic Obstructive Pulmonary Disease: An Update
Immunol Allergy Clin North Am. 2022 Aug;42(3):xiii-xiv. doi: 10.1016/j.iac.2022.04.010. Epub 2022 Jun 30.NO ABSTRACTPMID:35965055 | DOI:10.1016/j.iac.2022.04.010
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Nicola A Hanania Louis-Philippe Boulet Source Type: research

The Physiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap
Immunol Allergy Clin North Am. 2022 Aug;42(3):575-589. doi: 10.1016/j.iac.2022.04.001. Epub 2022 Jun 30.ABSTRACTAsthma and chronic obstructive pulmonary disease (COPD) are both characterized by airway obstruction and share similar clinical manifestations. However, they differ in many respects related to underlying cause, mechanism of airway obstruction, pattern and progression of symptoms, and response to therapy. It remains unclear whether there is a unique physiologic phenotype that characterizes asthma-COPD overlap (ACO). This review describes the common and distinct physiologic tests that help define asthma and COPD an...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: David A Kaminsky Charles G Irvin Source Type: research

Early Features of Chronic Obstructive Pulmonary Disease in Patients with Asthma: Is there ACO before ACO?
Immunol Allergy Clin North Am. 2022 Aug;42(3):549-558. doi: 10.1016/j.iac.2022.03.002.ABSTRACTThe diagnosis of asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is considered when a patient presents features of both asthma and COPD, usually including a component of irreversible airway obstruction (IRAO). However, some patients with asthma, particularly smokers, may have various features typical of COPD in the absence of such component of IRAO. Features of early COPD can be found at a young age in such patients even with normal spirometry. More longitudinal studies should be conducted to determine steps need...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Louis-Philippe Boulet Source Type: research

Asthma-Chronic Obstructive Pulmonary Disease: An Update
Immunol Allergy Clin North Am. 2022 Aug;42(3):xiii-xiv. doi: 10.1016/j.iac.2022.04.010. Epub 2022 Jun 30.NO ABSTRACTPMID:35965055 | DOI:10.1016/j.iac.2022.04.010
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Nicola A Hanania Louis-Philippe Boulet Source Type: research

The Physiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap
Immunol Allergy Clin North Am. 2022 Aug;42(3):575-589. doi: 10.1016/j.iac.2022.04.001. Epub 2022 Jun 30.ABSTRACTAsthma and chronic obstructive pulmonary disease (COPD) are both characterized by airway obstruction and share similar clinical manifestations. However, they differ in many respects related to underlying cause, mechanism of airway obstruction, pattern and progression of symptoms, and response to therapy. It remains unclear whether there is a unique physiologic phenotype that characterizes asthma-COPD overlap (ACO). This review describes the common and distinct physiologic tests that help define asthma and COPD an...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: David A Kaminsky Charles G Irvin Source Type: research

Early Features of Chronic Obstructive Pulmonary Disease in Patients with Asthma: Is there ACO before ACO?
Immunol Allergy Clin North Am. 2022 Aug;42(3):549-558. doi: 10.1016/j.iac.2022.03.002.ABSTRACTThe diagnosis of asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is considered when a patient presents features of both asthma and COPD, usually including a component of irreversible airway obstruction (IRAO). However, some patients with asthma, particularly smokers, may have various features typical of COPD in the absence of such component of IRAO. Features of early COPD can be found at a young age in such patients even with normal spirometry. More longitudinal studies should be conducted to determine steps need...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Louis-Philippe Boulet Source Type: research