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Condition: Chronic Obstructive Pulmonary

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Total 1666 results found since Jan 2013.

Asthma-Chronic Obstructive Pulmonary Disease: An Update
Immunol Allergy Clin North Am. 2022 Aug;42(3):xiii-xiv. doi: 10.1016/j.iac.2022.04.010. Epub 2022 Jun 30.NO ABSTRACTPMID:35965055 | DOI:10.1016/j.iac.2022.04.010
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Nicola A Hanania Louis-Philippe Boulet Source Type: research

The Physiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap
Immunol Allergy Clin North Am. 2022 Aug;42(3):575-589. doi: 10.1016/j.iac.2022.04.001. Epub 2022 Jun 30.ABSTRACTAsthma and chronic obstructive pulmonary disease (COPD) are both characterized by airway obstruction and share similar clinical manifestations. However, they differ in many respects related to underlying cause, mechanism of airway obstruction, pattern and progression of symptoms, and response to therapy. It remains unclear whether there is a unique physiologic phenotype that characterizes asthma-COPD overlap (ACO). This review describes the common and distinct physiologic tests that help define asthma and COPD an...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: David A Kaminsky Charles G Irvin Source Type: research

Early Features of Chronic Obstructive Pulmonary Disease in Patients with Asthma: Is there ACO before ACO?
Immunol Allergy Clin North Am. 2022 Aug;42(3):549-558. doi: 10.1016/j.iac.2022.03.002.ABSTRACTThe diagnosis of asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is considered when a patient presents features of both asthma and COPD, usually including a component of irreversible airway obstruction (IRAO). However, some patients with asthma, particularly smokers, may have various features typical of COPD in the absence of such component of IRAO. Features of early COPD can be found at a young age in such patients even with normal spirometry. More longitudinal studies should be conducted to determine steps need...
Source: The Medical Clinics of North America - August 14, 2022 Category: General Medicine Authors: Louis-Philippe Boulet Source Type: research

Trials Data on COPD Leave Primary Care Docs in the Dark Trials Data on COPD Leave Primary Care Docs in the Dark
Flare-ups and breathing difficulties were common among patients seen at primary care practices, suggesting a need for better evidence to guide treatment for the condition, a new analysis found.Medscape Medical News
Source: Medscape Allergy Headlines - August 8, 2022 Category: Allergy & Immunology Tags: Family Medicine/Primary Care News Source Type: news

Smaller Airways Set the Stage for Worse COPD Outcomes in Women
(MedPage Today) -- Smaller airways in women may explain their worse respiratory outcomes in chronic obstructive pulmonary disease (COPD), a large cohort study suggested. For never-smokers and ever-smokers alike, CT imaging revealed that men had...
Source: MedPage Today Allergy - August 2, 2022 Category: Allergy & Immunology Source Type: news

Asthma and COPD Overlap: An Update
IMMUNOLOGY AND ALLERGYCLINICS OF NORTH AMERICA
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Nicola A. Hanania, Louis-Philippe Boulet Source Type: research

Pharmacologic Management Strategies of Asthma-Chronic Obstructive Pulmonary Disease Overlap
The best therapeutic approach to patients with asthma-chronic obstructive pulmonary disease overlap (ACO) is unknown. Current treatment recommendations rely on expert opinions, roundtable discussions, and strategy documents, because patients with ACO have been excluded from most clinical studies in asthma and COPD. Because of the underlying asthma initial therapy, early use of inhaled corticosteroids along with a long-acting bronchodilator is recommended. If maintenance inhaler therapy is not effective, advanced therapies based on phenotyping and identification of treatable traits may be considered.
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Nicola A. Hanania, Marc Miravitlles Source Type: research

When Asthma and Chronic Obstructive Pulmonary Disease Overlap; Current Knowledge and Unmet Needs
Asthma and chronic obstructive pulmonary disease (COPD) are common diseases that often overlap. The term asthma-COPD overlap (ACO) has been used to define this entity but there remain several speculations on its exact definition, impact, pathophysiology, and clinical features. Patients with ACO have greater morbidity than those with asthma or COPD alone, but the information on the best therapeutic approach to this group of patients is still limited. Current treatment recommendations rely on expert opinions, roundtable discussions, and strategy documents. It is prudent to examine existing knowledge about ACO and determine t...
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Louis-Philippe Boulet, Nicola A. Hanania Source Type: research

Defining Asthma –Chronic Obstructive Pulmonary Disease Overlap
Much interest has been given to the asthma –chronic obstructive pulmonary disease (COPD) overlap (ACO) in the past 2 decades, but the condition is still ill-defined. There is general agreement that a patient with longstanding asthma who develops fixed airflow obstruction after years of smoking has ACO although defining asthma in the face o f COPD can be challenging. Many features of asthma are also found in patients with COPD without indicating an overlap and no consensus exists on which characteristics should be included in the definition of ACO. Nevertheless, some guidance has been issued to help clinicians and researc...
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Krystelle Godbout, Peter G. Gibson Source Type: research

Early Features of Chronic Obstructive Pulmonary Disease in Patients with Asthma
The diagnosis of asthma –chronic obstructive pulmonary disease (COPD) overlap (ACO) is considered when a patient presents features of both asthma and COPD, usually including a component of irreversible airway obstruction (IRAO). However, some patients with asthma, particularly smokers, may have various features typical o f COPD in the absence of such component of IRAO. Features of early COPD can be found at a young age in such patients even with normal spirometry. More longitudinal studies should be conducted to determine steps needed to improve clinical outcomes of these patients including the early recognition of these...
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Louis-Philippe Boulet Source Type: research

Epidemiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap
Asthma COPD Overlap has consistently reported to be associated with an increase burden of disease but the impact on lung function decline and mortality varies by study. The prevalence increases with age but the relationship with gender also varies with the study population. The variability in the prevalence and clinical characteristics of ACO is linked to differences in how chronic obstructive pulmonary disease (COPD) and asthma are defined, including diagnostic criteria (spirometry-based vs. clinical or symptom-based diagnoses vs. claims data), the population studied, the geographic region and environment and a consensus ...
Source: Immunology and Allergy Clinics of North America - August 1, 2022 Category: Allergy & Immunology Authors: Anne L. Fuhlbrigge Source Type: research

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