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Condition: Chronic Obstructive Pulmonary
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Total 1666 results found since Jan 2013.
Peripheral Blood Expressions of MicroRNA-146a and MicroRNA-218 in Chronic Obstructive Pulmonary Disease with/without Cigarette Smoke Exposure
Iran J Allergy Asthma Immunol. 2022 Aug 12;21(4):399-406. doi: 10.18502/ijaai.v21i4.10287.ABSTRACTAltered expression and dysregulation of microRNAs (miRNAs) have been reported in different samples of chronic obstructive pulmonary disease (COPD) patients. The present study attempted to evaluate the peripheral expressions of miR-146a and miR-218 in COPD patients and sex-matched healthy controls with/without cigarette smoke exposure (CSE). In this case-control study, blood samples were collected from 60 COPD patients (30 with CSE and 30 non-CSE in each group) and 60 healthy controls. Peripheral expressions of miRNA-146a and m...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 16, 2022 Category: Allergy & Immunology Authors: Ebrahim Nadi Ghazal Geramirad Zohreh Kahramfar Ashkan Rasuli-Saravani Ghasem Solgi Source Type: research
Airway-delivered short-chain fatty acid acetate boosts antiviral immunity during rhinovirus infection
Microbiota are recognised to play a major role in regulation of immunity through release of immunomodulatory metabolites such as short-chain fatty acids (SCFA). Rhinoviruses (RV) induce upper respiratory illnesses and precipitate exacerbations of asthma and chronic obstructive pulmonary disease through poorly understood mechanisms. Local interactions between SCFAs and antiviral immune responses in the respiratory tract have not been previously investigated.
Source: Journal of Allergy and Clinical Immunology - October 7, 2022 Category: Allergy & Immunology Authors: Krist Helen Antunes, Aran Singanayagam, Lily Williams, Tasnim Syakirah Faiez, Ana Farias, Millie M. Jackson, Fatima K. Faizi, Julia Aniscenko, Tatiana Kebadze, Punnam Chander Veerati, Lisa Wood, Nathan W. Bartlett, Ana Paula Duarte de Souza, Sebastian L. Source Type: research
Impact of former smoking exposure on airway eosinophilic activation and autoimmunity in patients with severe asthma
Conclusion
In patients with severe asthma, a former smoking history is associated with eosinophilic airway inflammation and activation and relative insensitivity to steroids, as well as airway autoimmunity.
Source: European Respiratory Journal - October 6, 2022 Category: Respiratory Medicine Authors: Klein, D. K., Silberbrandt, A., Frossing, L., Hvidtfeldt, M., von Bülow, A., Nair, P., Mukherjee, M., Porsbjerg, C. Tags: COPD and smoking, Asthma and allergy Original Articles: Asthma Source Type: research
Pulmonary Rehabilitation for COPD in a Low Resource Setting Pulmonary Rehabilitation for COPD in a Low Resource Setting
Could this program help COPD patients access pulmonary rehabilitation services in areas with limited resources?BMC Pulmonary Medicine
Source: Medscape Allergy Headlines - October 3, 2022 Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news
Differentiating COPD and asthma using quantitative CT imaging and machine learning
Conclusion
COPD and asthma can be differentiated using machine learning with moderate-to-high accuracy by a subset of only seven CT features.
Source: European Respiratory Journal - September 22, 2022 Category: Respiratory Medicine Authors: Moslemi, A., Kontogianni, K., Brock, J., Wood, S., Herth, F., Kirby, M. Tags: COPD and smoking, Lung imaging, Asthma and allergy Original Articles: Airway diseases and imaging Source Type: research
Derivation and validation of the UCAP-Q case-finding questionnaire to detect undiagnosed asthma and COPD
Conclusions
The UCAP-Q demonstrated high sensitivities and AUCs for identifying undiagnosed asthma or COPD. A web-based calculator allows for easy calculation of risk probabilities for each disease.
Source: European Respiratory Journal - September 22, 2022 Category: Respiratory Medicine Authors: Huynh, C., Whitmore, G. A., Vandemheen, K. L., FitzGerald, J. M., Bergeron, C., Boulet, L.-P., Cote, A., Field, S. K., Penz, E., McIvor, R. A., Lemiere, C., Gupta, S., Mayers, I., Bhutani, M., Hernandez, P., Lougheed, M. D., Licskai, C. J., Azher, T., Ain Tags: COPD and smoking, Asthma and allergy Original Articles: Airway diseases Source Type: research
Spirometry May Aid Diagnosis of Asthma Versus COPD in Primary Care
Adding diagnostics available in primary care to model using only patient history showed improvement in diagnostic differentiation
Source: Pulmonary Medicine News - Doctors Lounge - September 15, 2022 Category: Respiratory Medicine Tags: Family Medicine, Internal Medicine, Allergy, Pulmonology, Journal, Source Type: news
Narrative Review of the Role of Patient-Reported Outcomes and Inhaler Handling Errors in the Control of Asthma and COPD
AbstractPurpose of ReviewAsthma and chronic obstructive pulmonary disease (COPD) are chronic respiratory diseases that remain uncontrolled in many patients, despite the wide range of therapeutic options available. This review analyzes the available clinical evidence on 3 budesonide/formoterol DPI devices, Spiromax®, Turbuhaler®, and Easyhaler®, in terms of patient-reported outcomes (PROs), inhaler errors, and asthma and COPD control.Recent FindingsThe effectiveness of dry powder inhalers (DPI) depends largely on the device and the patient ’s inhaler technique. Equally important are the patient’s perception of the in...
Source: Current Allergy and Asthma Reports - September 10, 2022 Category: Allergy & Immunology Source Type: research
Are Antibiotics Needed for Moderate Acute Exacerbations of COPD?
(MedPage Today) -- BARCELONA -- The need for antibiotics in patients with chronic obstructive pulmonary disease (COPD) seeking treatment for moderate acute COPD exacerbations could not be ruled out in a randomized trial from Germany, except perhaps...
Source: MedPage Today Allergy - September 7, 2022 Category: Allergy & Immunology Source Type: news
