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The Dynamic Contribution of Neutrophils in the Chronic Respiratory Diseases
Allergy Asthma Immunol Res. 2022 Jul;14(4):361-378. doi: 10.4168/aair.2022.14.4.361.ABSTRACTAsthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis are representative chronic respiratory diseases (CRDs). Although they differ in terms of disease presentation, they are all thought to arise from unresolved inflammation. Neutrophils are not only the first responders to acute inflammation, but they also help resolve the inflammation. Notably, emerging clinical studies show that CRDs are associated with systemic and local elevation of neutrophils. Moreover, murine studies suggest that airway-infiltrating...
Source: Allergy, Asthma and Immunology Research - July 15, 2022 Category: Allergy & Immunology Authors: Jongho Ham Jihyun Kim Young Gyun Ko Hye Young Kim Source Type: research