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Improvement in Lung Clearance Index and Chest CT Scores with Elexacaftor/Tezacaftor/Ivacaftor Treatment in People with Cystic Fibrosis Aged 12 Years and Older - The RECOVER Study
CONCLUSIONS: ETI is associated with substantial improvements in LCI2.5, spirometry and PRAGMA-CF CT scores in people with CF aged 12 years and older. ETI led to improved nutrition and quality of life. People in the F508del/F508del group have significantly lower sweat chloride on ETI treatment compared to the F508del/MF group. Clinical trial registration available at www.CLINICALTRIALS: gov, ID: NCT04602468.PMID:37703083 | DOI:10.1164/rccm.202308-1317OC
Source: Am J Respir Crit Car... - September 13, 2023 Category: Intensive Care Authors: Paul McNally Karen Lester Gavin Stone Basil Elnazir Michael Williamson Des Cox Barry Linnane Laura Kirwan David Rea Paul O'Regan Tom Semple Clare Saunders Harm A W M Tiddens Edward McKone Jane C Davies Source Type: research
Availability of calorie information on online menus from chain restaurants in the USA: current prevalence and legal landscape
CONCLUSIONS: As consumers increasingly rely on TPP for restaurant ordering, menus on these platforms should include calories in order to promote transparency and nutrition.PMID:37700624 | DOI:10.1017/S1368980023001799
Source: Public Health Nutrition - September 13, 2023 Category: International Medicine & Public Health Authors: Eva Greenthal Sarah Sorscher Jennifer L Pomeranz Sean B Cash Source Type: research
Contribution of school meals to the recommended nutrient and energy intake of children enrolled in the National Homegrown School Feeding Program in Zaria, Nigeria
CONCLUSION: The meals served through the NHSFP contributed at least 33% of the RNI for energy, protein, iron, calcium, sodium, vitamin A, and zinc. However, they could not meet the 33% of the RNI for carbohydrates, fiber, potassium, and vitamin C. Increasing the portion sizes and the diversity of the meals can address the suboptimal contribution of the meals to the RNI for carbohydrates, fiber, potassium, and vitamin C.PMID:37704525 | DOI:10.1016/j.arcped.2023.07.004
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Halliru Zailani Olumuyiwa Adeyemi Owolabi Abdullahi Balarabe Sallau Source Type: research
Association between Expanded Disability Status Scale score and dietary antioxidant capacity in patients with multiple sclerosis
Braz J Med Biol Res. 2023 Sep 8;56:e12776. doi: 10.1590/1414-431X2023e12776. eCollection 2023.ABSTRACTMultiple sclerosis (MS), a neuroinflammation that results in neurodegeneration, is the most prevalent central nervous system inflammatory disease in young people. A diet rich in antioxidants is known to decrease the production/activity of pro-inflammatory cytokines and have a positive impact on the prognosis of MS. The purpose of this study was to assess if dietary antioxidant capacity is related to Expanded Disability Status Scale (EDSS) scores in patients with MS. Patients with MS (n=220; 137 women and 83 men) were asked...
Source: Braz J Med Biol Res - September 13, 2023 Category: Research Authors: S Mungan I Guzel B C Demirdogen Source Type: research
The prevalence and multilevel analysis of minimum dietary diversity intake and its determinants among 6-23 months old infants in The Gambia: further analysis of the Gambian demographic and health survey data
CONCLUSION: The World Health Organization dietary evaluation tool suggests that the MDD value be extremely low, even though it might be slightly higher than the numbers for some nations. The country may need to take drastic measures to tackle child malnutrition.PMID:37705103 | DOI:10.1186/s41043-023-00442-x
Source: Journal of Health, Population, and Nutrition - September 13, 2023 Category: International Medicine & Public Health Authors: Bewuketu Terefe Mahlet Moges Jembere Nega Tezera Assimamaw Source Type: research
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
Cell Metab. 2023 Sep 7:S1550-4131(23)00304-2. doi: 10.1016/j.cmet.2023.08.009. Online ahead of print.ABSTRACTWeight regain after weight loss is a major challenge in the treatment of obesity. Immune cells adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain unclear. Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it. These cells, accumulating metabolic ...
Source: Cell Metabolism - September 13, 2023 Category: Cytology Authors: Hai-Yan Zhou Xu Feng Li-Wen Wang Rui Zhou Heng Sun Xin Chen Ren-Bin Lu Yan Huang Qi Guo Xiang-Hang Luo Source Type: research
Improvement in Lung Clearance Index and Chest CT Scores with Elexacaftor/Tezacaftor/Ivacaftor Treatment in People with Cystic Fibrosis Aged 12 Years and Older - The RECOVER Study
CONCLUSIONS: ETI is associated with substantial improvements in LCI2.5, spirometry and PRAGMA-CF CT scores in people with CF aged 12 years and older. ETI led to improved nutrition and quality of life. People in the F508del/F508del group have significantly lower sweat chloride on ETI treatment compared to the F508del/MF group. Clinical trial registration available at www.CLINICALTRIALS: gov, ID: NCT04602468.PMID:37703083 | DOI:10.1164/rccm.202308-1317OC
Source: Respiratory Care - September 13, 2023 Category: Respiratory Medicine Authors: Paul McNally Karen Lester Gavin Stone Basil Elnazir Michael Williamson Des Cox Barry Linnane Laura Kirwan David Rea Paul O'Regan Tom Semple Clare Saunders Harm A W M Tiddens Edward McKone Jane C Davies Source Type: research
The association of the serum levels of aldehydes with diabetes-related eye diseases: a cross-sectional population-based study
Environ Sci Pollut Res Int. 2023 Sep 14. doi: 10.1007/s11356-023-29750-9. Online ahead of print.ABSTRACTDiabetes could impact many ocular tissues. However, the association of the serum aldehydes with diabetes-related eye diseases (DED) remains unclear. Thus, we aimed to examine the above relationship from the general US population of 2013-2014 National Health and Nutrition Examination Survey (NHANES). The multivariable logistic regression and Bayesian kernel machine regression (BKMR) were used to analyze the effect of serum aldehydes on the risk of DED. Pearson's correlation analysis, the restricted cubic spline (RCS) mode...
Source: Environmental Science and Pollution Research International - September 13, 2023 Category: Environmental Health Authors: Weiming Yan Yan Sun Yutong Wang Yubin Liu Weihua Yan Dongling Li Meizhu Chen Source Type: research
The prevalence and multilevel analysis of minimum dietary diversity intake and its determinants among 6-23 months old infants in The Gambia: further analysis of the Gambian demographic and health survey data
CONCLUSION: The World Health Organization dietary evaluation tool suggests that the MDD value be extremely low, even though it might be slightly higher than the numbers for some nations. The country may need to take drastic measures to tackle child malnutrition.PMID:37705103 | PMC:PMC10498527 | DOI:10.1186/s41043-023-00442-x
Source: Journal of Health, Population, and Nutrition - September 13, 2023 Category: International Medicine & Public Health Authors: Bewuketu Terefe Mahlet Moges Jembere Nega Tezera Assimamaw Source Type: research
Possible beneficial interactions of ciliated protozoans with coral health and resilience
Appl Environ Microbiol. 2023 Sep 13:e0121723. doi: 10.1128/aem.01217-23. Online ahead of print.ABSTRACTMicrobial interactions contribute significantly to coral health in the marine environment. Most beneficial associations have been described with their bacterial communities, but knowledge of beneficial associations between protozoan ciliates and corals is still lacking. Ciliates are important bacterial predators and provide nutrition to higher trophic-level organisms. The mucus secreted by corals and the microenvironment of the coral surface layer attract ciliates based on their food preferences. The mixotrophic and heter...
Source: Applied and Environmental Microbiology - September 13, 2023 Category: Microbiology Authors: Chinnarajan Ravindran Lawrance Irudayarajan Haritha P Raveendran Source Type: research
A fluorescence biosensor for tyrosinase activity analysis based on silicon-doped carbon quantum dots
Chem Pharm Bull (Tokyo). 2023 Sep 14. doi: 10.1248/cpb.c23-00410. Online ahead of print.ABSTRACTTyrosinase (TYR) plays a pivotal role in the biosynthesis of melanin, and its activity level holds critical implications for vitiligo, melanoma cancer, and food nutritional value. The sensitive determination of TYR activity is of great significance for both fundamental research and clinical investigations. In this work, we successfully synthesized silicon-doped carbon quantum dots (Si-CQDs) through a one-pot hydrothermal method with trans-aconitic acid as carbon source and N-[3-(Trimethoxysilyl)propyl]ethylenediamine as the dopa...
Source: Chemical and Pharmaceutical Bulletin - September 13, 2023 Category: Drugs & Pharmacology Authors: Qiang Chen Lili Zheng Xiaoqin Deng Menghan Zhang Wendi Han Zhengjun Huang Chenfang Miao Shaohuang Weng Source Type: research
Longitudinal Growth and Undernutrition Burden Among Term Low Birth Weight Newborns Reared in Adverse Socioeconomic Conditions in Delhi
CONCLUSION: With appropriate counselling of parents, term low birth weight infants reared under adverse socioeconomic conditions show substantial catch-up growth in BMIZ and WAZ but not in HAZ. The long-term consequences of this excess weight over length gain need focused evaluation.PMID:37700585
Source: Indian Pediatrics - September 13, 2023 Category: Pediatrics Authors: Manpreet Kaur Geeta Trilok-Kumar Sikha Sinha Suzanne Filteau Anura V Kurpad Clive Osmond Harshpal Singh Sachdev Source Type: research
Quality analysis of the clinical laboratory literature and its effectiveness on clinical quality improvement: a systematic review
J Clin Biochem Nutr. 2023 Sep;73(2):108-115. doi: 10.3164/jcbn.23-22. Epub 2023 Jul 7.ABSTRACTQuality improvement in clinical laboratories is crucial to ensure accurate and reliable test results. With increasing awareness of the potential adverse effects of errors in laboratory practice on patient outcomes, the need for continual improvement of laboratory services cannot be overemphasized. A literature search was conducted on PubMed and a web of science core collection between October and February 2021 to evaluate the scientific literature quality of clinical laboratory quality improvement; only peer-reviewed articles writ...
Source: Journal of Clinical Biochemistry and Nutrition - September 13, 2023 Category: Nutrition Authors: Ahmed Shabbir Chaudhry Yu Inata Etsuko Nakagami-Yamaguchi Source Type: research
Postoperative Growth and Brain Injury Outcomes in Spontaneous Intestinal Perforation vs Surgical Necrotizing Enterocolitis in Preterm Infants
CONCLUSION: In our cohort, preterm infants with SIP and sNEC did not show significant differences in postoperative morbidity and brain MRI abnormalities at term equivalent age. sNEC had lower discharge weight z scores. Larger prospective studies are needed for confirmation of these findings.PMID:37700582
Source: Indian Pediatrics - September 13, 2023 Category: Pediatrics Authors: Parvesh Mohan Garg Katheryn Lett Md Abu Yusuf Ansari Isabella Pittman Robin Riddick Neha Varshney Michael Morris David Sawaya Charlotte Taylor Kartik Reddy Peter Porcelli William Hillegass Source Type: research
Cooking Skills: Essential for the Food is Medicine Movement
Am J Clin Nutr. 2023 Sep 11:S0002-9165(23)66127-1. doi: 10.1016/j.ajcnut.2023.08.026. Online ahead of print.NO ABSTRACTPMID:37704016 | DOI:10.1016/j.ajcnut.2023.08.026
Source: The American Journal of Clinical Nutrition - September 13, 2023 Category: Nutrition Authors: Deborah D Kennedy Source Type: research
