Association between the arm-to-choroidal circulation time and clinical profile in patients with polypoidal choroidal vasculopathy
ConclusionPatients with PCV and ACT>20 s are more likely to experience exudative change recurrence in the retina during treatment because they have more polypoidal lesions. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 13, 2024 Category: Opthalmology Source Type: research

Correlation between extraocular muscle enlargement and thyroid autoantibodies in thyroid eye disease
ConclusionsTSAb showed significant associations with extraocular muscle enlargement. Measurement of TSAb, rather than of TRAb, may be more useful for diagnosing extraocular muscle enlargement in patients with TED. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 13, 2024 Category: Opthalmology Source Type: research

Extraction of three-dimensional shapes in glaucoma patients in response to monocular depth cues
ConclusionsThe 3D shape perception in glaucoma patients varies based on the depth cue's characteristics. Impaired 1D discrimination and larger thresholds for 3D-SfM in glaucoma patients with a 100% VFI for binocular-VFS indicate more pronounced perceptual deficits of lower-level elementary features for 3D-SfS and higher-level visual processing of 3D shapes for 3D-SfM. The effects of the location and degree of binocular visual-field defects on 3D shape perception remain to be elucidated. Our research provides insights into the 3D shape extraction mechanism in glaucoma. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 10, 2024 Category: Opthalmology Source Type: research

Selective internal limiting membrane peeling for prevention of secondary epiretinal membrane after vitrectomy for rhegmatogenous retinal detachment
ConclusionSelective ILM peeling offers an alternative option to reduce the burden of ILM peeling or additional surgery. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 10, 2024 Category: Opthalmology Source Type: research

Intrascleral intraocular lens fixation with ab interno trabeculotomy in patients with exfoliation glaucoma with lens subluxation
ConclusionIntrascleral IOL fixation combined with microhook LOT is a promising option in cases of exfoliation glaucoma with subluxated lens/IOL; however, the high rate of postoperative hyphema and vitreous hemorrhage should be noted. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 8, 2024 Category: Opthalmology Source Type: research

Three-year efficacy and safety of omidenepag isopropyl in patients with normal tension glaucoma
ConclusionAfter the administration of omidenepag isopropyl, IOP in patients with NTG decreased within 3 years, visual fields were maintained, and safety was satisfactory. Thus, omidenepag isopropyl can be used as the first-line treatment for patients with NTG. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 8, 2024 Category: Opthalmology Source Type: research

Nationwide epidemiologic survey on incidence of macular dystrophy in Japan
ConclusionThis was the first nationwide survey of macular dystrophy in Japan and provided an approximate number of affected patients. The diagnosis of macular dystrophy is primarily carried out at facilities with affiliated specialists, such as university hospitals. By examining the incidence of multiple diseases simultaneously, we were able to compare the incidence of each type of macular dystrophy. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 3, 2024 Category: Opthalmology Source Type: research

Electroretinography in congenital nystagmus patients with a normal fundus examination
ConclusionsIn Korean congenital nystagmus patients with a normal fundus examination, achromatopsia and Leber ’s congenital amaurosis are uncommon causes. ERG is needed to make a definite diagnosis and provide prognostic information in congenital idiopathic nystagmus patients with a normal fundus examination. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 3, 2024 Category: Opthalmology Source Type: research

Evaluation of the results of contact lens assisted corneal cross-linking treatment in keratoconus patients with thin corneas
ConclusionsAccelerated CA-CXL with Lotrafilcon B and Comfilcon A silicone hydrogel lenses is a safe and effective method to stop progression in patients with thin corneas. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 1, 2024 Category: Opthalmology Source Type: research

Evaluation of pericardium patch graft thickness in patients with Ahmed glaucoma valve implantation: an anterior segment OCT study
ConclusionAlthough the most evident thinning of the layers covering the tube was observed in the early postoperative period, PPG showed a stable decrease even in the late period. The progressive reduction in the PPG thickness observed also in the peripheral region indicates that factors beyond mechanical forces contribute to this degenerative process. AS-OCT could be a valuable non-invasive tool in clarifying this process. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - March 30, 2024 Category: Opthalmology Source Type: research

Comparative study of surgical outcomes regarding tear meniscus area and high-order aberrations between two different interventional methods for primary acquired nasolacrimal duct obstruction
ConclusionAlthough both EN-DCR and SG-BCI are effective for PANDO, our results suggest that EN-DCR is more effective in improving TMA and HOAs. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - March 19, 2024 Category: Opthalmology Source Type: research

Aging-associated changes of optical coherence tomography-measured ganglion cell-related retinal layer thickness and visual sensitivity in normal Japanese
ConclusionWe report that aging-associated change rates of cpRNFLT, MGCIPLT and MGCCT in normal Japanese eyes were found to be significantly accelerated along with aging. Relationship between VF sensitivity decline rates and SD-OCT measured GCIPLT decline rates during physiological aging in the corresponding parafoveal retinal areas are also documented. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - March 18, 2024 Category: Opthalmology Source Type: research

Analysis of the progression rate of idiopathic macular holes and the optimal cut-off for baseline minimum linear diameter and base diameter
ConclusionThe group without PVD progressed faster than the group with PVD. Moreover, the progression rates were faster in MHs with MLD  <  306.0 μm and BD <  470.0 μm. In these patients, vitrectomy without delay is expected to improve the visual prognosis. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research

Intraocular pressure changes during intravitreal aflibercept injection based on treat-and-extend regimen in Japanese patients with neovascular age-related macular degeneration and glaucoma
ConclusionOur results suggest that intravitreal aflibercept injections may be beneficial for patients with nAMD complicated by glaucoma. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 6, 2024 Category: Opthalmology Source Type: research

Levofloxacin susceptibility of Staphylococci from conjunctiva in patients with atopic dermatitis
ConclusionDistinctive bacterial distribution and drug resistance need consideration in the managing of ocular disorders among patients with AD. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research