National survey of amblyopia treatment in Japan: comparison with amblyopia treatment study results of the pediatric eye disease investigator group
ConclusionThe amblyopia treatment in Japan survey did not always agree with the research results of the ATS. Japanese ophthalmologists tend to make treatment plans for amblyopia according to their clinical experience. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - December 12, 2022 Category: Opthalmology Source Type: research

Recent trends in anti-vascular endothelial growth factor intravitreal injections: a large claims database study in Japan
ConclusionThese findings can be used as a benchmark for the clinical practice of anti-VEGF therapy. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - December 12, 2022 Category: Opthalmology Source Type: research

Differentiating drusen and drusenoid deposits subtypes on multimodal imaging and risk of advanced age-related macular degeneration
AbstractDrusen are extracellular material considered a precursor lesion to advanced age-related macular degeneration (AMD), located either on the retinal pigment epithelium (RPE) or the sub-RPE; they contain various proteins associated with inflammation and lipids. Previous studies suggest that the lifecycle of drusen varies depending on drusen type and size. In general, conventional drusen grow and aggregate/coalesce in the first stage, and in the second stage, they regress with or without showing RPE atrophy. The risk of advanced AMD also varies depending on the drusen and drusenoid deposit types ’ along with their siz...
Source: Japanese Journal of Ophthalmology - December 7, 2022 Category: Opthalmology Source Type: research

Microhook ab interno trabeculotomy for secondary glaucoma in patients with hereditary transthyretin amyloidosis
ConclusionµLOT for secondary glaucoma in ATTRv is safe and effective 1 year after surgery, but the effects diminish after 2 years. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 28, 2022 Category: Opthalmology Source Type: research

A multicenter study of ocular inflammation after COVID-19 vaccination
ConclusionsCOVID-19 vaccination can be related to various types of ocular inflammatory events. When we encounter patients with ocular inflammatory disease, we should consider that it may be an adverse effect of COVID-19 vaccination. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 22, 2022 Category: Opthalmology Source Type: research

Postoperative large intraretinal cavity and schisis with paravascular inner break in high myopia
ConclusionLarge intraretinal cavities and schisis can be observed after MTM surgery, associated with paravascular inner breaks. The condition can progress after a long stable period; therefore, continuous follow-up is necessary. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 19, 2022 Category: Opthalmology Source Type: research

Correction to: Analysis of treatment protocols using azithromycin eye drops for bacterial blepharitis: second report —bacteriological investigation
(Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 14, 2022 Category: Opthalmology Source Type: research

Displacement of the retina and changes in the foveal avascular zone area after internal limiting membrane peeling for epiretinal membrane
ConclusionILM peeling during vitrectomy for ERM caused larger displacement of the inner and smaller displacement of the outer retinas, towards the optic disc. Postoperative changes in the FAZ area were dependent on the baseline FAZ area, but not on the foveal displacement. ILM may physiologically exert centrifugal tractional forces on the fovea. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 12, 2022 Category: Opthalmology Source Type: research

Atypical stromal herpes simplex keratitis: clinical features and diagnosis
ConclusionThe appearance of an atypical stromal HSK represents a diagnostic challenge. Tear HSV-sIgA test could help provide a quick diagnosis. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 11, 2022 Category: Opthalmology Source Type: research

UbiA prenyltransferase domain-containing protein 1 (UBIAD1) variant c.695  A  & gt;  G identified in a multigenerational Japanese family with Schnyder corneal dystrophy
ConclusionThis is the first report on the pathogenicUBIAD1 variation c.695  A >  G (p.Asn232Ser) in a Japanese population. SCD is a rare corneal dystrophy, and further research on additional cases will aid in the elucidation of disease mechanisms and development of therapeutic strategies. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 11, 2022 Category: Opthalmology Source Type: research

Two-year clinical outcomes of triple therapy with photodynamic therapy, anti-vascular endothelial growth factor agent, and triamcinolone acetonide for neovascular age-related macular degeneration
ConclusionIn nAMD patients, induction treatment with triple therapy resulted in approximately 40% of the patients requiring no retreatment for 2 years. The type of anti-VEGF agents used made no difference in the results. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 8, 2022 Category: Opthalmology Source Type: research

Modified inverted internal limiting membrane flap technique for macular hole closure
ConclusionThe modified inverted ILM flap technique combined with vitreous surgery was an effective method for treating macular holes, resulting in improvement in closure and visual acuity. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 8, 2022 Category: Opthalmology Source Type: research

Epidemiology and characteristics of common forms of anterior uveitis at initial presentation in a tertiary facility in Japan
ConclusionThe most frequent AU was AAU, followed by herpetic AU. Herpetic AU patients were older and had higher intraocular pressure than AAU patients, although VA was equally impaired in both groups. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 8, 2022 Category: Opthalmology Source Type: research

Exophthalmos associated with chronic progressive external ophthalmoplegia
(Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 8, 2022 Category: Opthalmology Source Type: research

Publisher Correction to: Outer retinal microstructure and visual function after macular hole surgery with and without Brilliant Blue G
(Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 3, 2022 Category: Opthalmology Source Type: research