Intraocular pressure changes during intravitreal aflibercept injection based on treat-and-extend regimen in Japanese patients with neovascular age-related macular degeneration and glaucoma
ConclusionOur results suggest that intravitreal aflibercept injections may be beneficial for patients with nAMD complicated by glaucoma. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 6, 2024 Category: Opthalmology Source Type: research
Levofloxacin susceptibility of Staphylococci from conjunctiva in patients with atopic dermatitis
ConclusionDistinctive bacterial distribution and drug resistance need consideration in the managing of ocular disorders among patients with AD. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research
Injectable in situ cross-linking hyaluronan hydrogel for easier removal of posterior vitreous cortex in vitrectomy
ConclusionThe results indicate that XL-HA is a potential adjunctive device to help make vitrectomy safe, effective, and successful. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research
Two-year outcomes of anterior versus posterior scleral application of mitomycin C-soaked sponge in trabeculectomy
ConclusionAlthough there were similar success rates, the posterior scleral application of MMC-soaked sponge with trabeculectomy was safer with a better bleb morphology than the anterior scleral application. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research
The existence of senescent cells in conjunctival epithelium from elderly individuals
ConclusionsSenescent cells accumulate with age in the conjunctival epithelium, accompanied by a decrease in Ki67, p63 and ZO-1 expressing cells. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research
Color enhancement and achromatization to increase the visibility of indocyanine green-stained internal limiting membrane during digitally assisted vitreoretinal surgery
ConclusionColor enhancement and achromatization using DAV may offer potential advantages to enhance the visibility of ICG-stained ILM. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - February 5, 2024 Category: Opthalmology Source Type: research
Fundus examination using a wide-angle viewing system and intraocular illumination through the corneal incision during cataract surgery: a case series
ConclusionThe described technique may reduce the disadvantages of creating scleral incisions and provide comparable visibility to inserting the illuminator into the vitreous cavity. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - January 30, 2024 Category: Opthalmology Source Type: research
One-year results of treat-and-extend regimen with intravitreal faricimab for treatment-na ïve neovascular age-related macular degeneration
ConclusionsA loading phase treatment followed by a TAE regimen with intravitreal faricimab appears to be generally safe and effective for improving visual acuity and ameliorating exudative changes in eyes with nAMD. However, there might be cases in which exudative changes cannot be adequately controlled with injections of faricimab every 8 weeks in the maintenance phase. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - January 20, 2024 Category: Opthalmology Source Type: research
Descemet stripping automated endothelial keratoplasty via a frown incision
ConclusionsA sclerocorneal frown incision is useful for performing DSAEK with an NS Endo-Inserter as it does not affect endothelial cell loss despite its short incision width. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - January 2, 2024 Category: Opthalmology Source Type: research
A novel bleb revision technique: lining with tenon ’s patch graft for treatment of large, ischemic, leaking blebs with severe conjunctival scarring after trabeculectomy
ConclusionTenon ’s patch-lining technique is a promising method for bleb leakage with large ischemic bleb and impractical conjunctival mobilization. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - December 12, 2023 Category: Opthalmology Source Type: research
Genotypes and clinical features of RHO-associated retinitis pigmentosa in a Japanese population
Conclusionp.[Pro23Leu], but not p.[Pro23His], was a frequent variant causingRHO-RP in the Kyushu region of Japan. As reported in previous studies, patients with the p.[Pro347Leu] variant showed a more severe phenotype, and variants causing sectorRHO-RP were associated with a good prognosis. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - December 9, 2023 Category: Opthalmology Source Type: research
Clinical features of 26 cases of COVID-19-associated conjunctivitis
ConclusionsCOVID-19-associated conjunctivitis is rare in the elderly and strongly associated with a history of smoking. It often occurs in the early stages of infection, and while hyperemia is recognized as a clinical symptom, other ocular symptoms are rare or non-existent. Many cases recover within a short time. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 29, 2023 Category: Opthalmology Source Type: research
Vitreomacular traction in diabetic retinopathy
ConclusionsVMT in DR had a thickened posterior hyaloid, and many of them had multi-layered traction and/or concurrent macular retinoschisis. Lamellar macular hole, full-thickness macular hole, or concurrent retinal detachment may also occur. Spontaneous resolution of VMT rarely occurred, and those who underwent operation for VMT had improved vision and macular structures with resolution of the macular hole and retinal detachment. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 25, 2023 Category: Opthalmology Source Type: research
Corneal refractive error and astigmatism in patients aged 6 to 18 years with a history of retinopathy of prematurity and birth weight of & lt;1500 g
ConclusionCR was significantly higher in the sr-ROP (p=0.013) and PC-ROP (p<0.001) groups than in the NBW group. The PC-ROP group had significantly more AS than the sr-ROP group. There was a strong correlation between the anterior and posterior CR and AS. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 25, 2023 Category: Opthalmology Source Type: research
Relationship between strabismus associated with Angelman syndrome and orbital anomaly
ConclusionsThe frequency of exotropia in AS is higher than previously reported, with our results strongly suggesting that the enlarged biorbital angle is related to the pathogenesis of exotropia in AS. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 25, 2023 Category: Opthalmology Source Type: research
