Effectiveness of intraoperative optical coherence tomography on vitrectomy for proliferative diabetic retinopathy
ConclusionUse of iOCT reduced the operation time without affecting the incidence rates of intraoperative and postoperative complications, reoperation ratios, or postoperative visual acuities in patients who underwent vitreous surgery for PDR. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - November 1, 2022 Category: Opthalmology Source Type: research

Analysis of Meibomian Glands in Juvenile Systemic Lupus Erythematosus Patients without Dry Eye Symptoms and Signs
ConclusionMeibomian gland loss could be observed in JSLE patients with no clinical signs and symptoms of dry eye. Considering the longer life expectancy of children, the positive correlation of disease duration with the meibomian gland reveals the importance of routine eye examinations from the diagnosis of the disease. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 31, 2022 Category: Opthalmology Source Type: research

Scientific Reviewers
(Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 29, 2022 Category: Opthalmology Source Type: research

Vision-related quality of life and subscale items following intravitreal ranibizumab injections for central retinal vein occlusion
ConclusionVision-related QOL was low in patients with CRVO before treatment and improved with IVR. In spite of the improvements, several subscale items remained lower than in normal controls following treatment. Attention should be paid to the patients with CRVO and their decreased visual, social and psychological QOL. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 27, 2022 Category: Opthalmology Source Type: research

Treatment of recurrent high myopic macular hole associated with retinal detachment using a human amniotic membrane
ConclusionHuman amniotic membrane patches can effectively repair macular hole retinal detachment in high myopic eyes in terms of anatomic results and BCVA recovery. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 27, 2022 Category: Opthalmology Source Type: research

One-year recurrence rate of Graves ophthalmopathy presenting as diplopia in the primary position after varied doses of intravenous methylprednisolone followed by oral prednisolone with dosing based on the magnetic resonance imaging findings
ConclusionThis study showed that in 20% of patients, GO recurred within 1 year of administration of varied doses of IVMP, with the dosing based on the MRI findings. Furthermore, assessment of inflammation by use of MRI after 6 g of IVMP has a potential role in predicting recurrence. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 27, 2022 Category: Opthalmology Source Type: research

Association between central serous chorioretinopathy susceptibility genes and choroidal parameters
ConclusionCFH,VIPR2,TNFRSF10A, andGATA5 showed different association patterns with choroidal parameters. Although the mechanism of CSC pathogenesis by choroidal changes is not fully understood, this finding suggests that each gene may be involved in different mechanisms of CSC development. Our genetic study provides a basis for understanding the role of CSC susceptibility genes. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 1, 2022 Category: Opthalmology Source Type: research

Analysis of treatment protocols using azithromycin eye drops for bacterial blepharitis: second report —bacteriological investigation
ConclusionOur study suggests that in blepharitis pathogenicity is characterized by increased strain numbers and amounts of indigenous bacteria. Administering a 1% azithromycin ophthalmic solution suppresses the number of bacterial strains within 1 month after the end of eye drop administration without increasing drug resistance. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 1, 2022 Category: Opthalmology Source Type: research

Outer retinal microstructure and visual function after macular hole surgery with and without Brilliant Blue G
ConclusionEyes undergoing BBG-assisted MH surgery achieved faster recovery of the outer retinal structures and greater visual improvement than those of eyes without BBG. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - October 1, 2022 Category: Opthalmology Source Type: research

Japan Ocular Imaging Registry: a national ophthalmology real-world database
AbstractIn 2017, the Japanese Ophthalmological Society (JOS) created the Japan Ocular Imaging (JOI) registry, a national database of images and clinical data in the field of ophthalmology in Japan. The JOI registry automatically transfers the information stored in the electronic medical records of each institution to the cloud storage governed by the JOS. This process adheres to Japanese laws and regulations such as the Act on the Protection of Personal Information and the relevant laws of Japan, the Ethical Guidelines for Medical and Biological Research Involving Human Subjects, and the Medical Information System Security...
Source: Japanese Journal of Ophthalmology - September 23, 2022 Category: Opthalmology Source Type: research

Short-term outcomes of switching to brolucizumab in japanese patients with neovascular age-related macular degeneration
ConclusionSwitching to brolucizumab from aflibercept using a TAE regimen might be effective for maintaining functional outcomes and extending intervals in Japanese patients with AMD. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - September 23, 2022 Category: Opthalmology Source Type: research

Intraocular pressure at different gaze positions in patients with highly myopic strabismus
ConclusionThe IOP of patients with HMS changes dramatically on side gazes, therefore, care should be taken while measuring IOP. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - September 9, 2022 Category: Opthalmology Source Type: research

Factors associated with recurrence of bleb-related infections
ConclusionWe recommend close observations when a bleb leakage is detected after the BRI has resolved. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - August 17, 2022 Category: Opthalmology Source Type: research

Short-term outcomes of micropulse transscleral laser therapy using the revised delivery probe in refractory glaucoma
ConclusionMP-TLT using the revised MicroPulse P3® Delivery Device for the treatment of refractory glaucoma was effective in reducing IOP across glaucoma types with an excellent safety profile and was well-tolerated by the patients. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - August 17, 2022 Category: Opthalmology Source Type: research

Agreement in the detection of chiasmal and postchiasmal visual field defects between imo binocular random single-eye test and Humphrey monocular test
ConclusionBRSET detected VF defects due to C/PCLs as accurately as the HFA monocular test with a shorter test duration. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - August 16, 2022 Category: Opthalmology Source Type: research