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Nutrition: Antidoxidants
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Total 54862 results found since Jan 2013.
Thymoquinone attenuates olanzapine-induced metabolic disorders in rats
CONCLUSIONS: The present study demonstrates the effectiveness of TQ on OLZ-induced metabolic abnormalities related to its antioxidant activity and regulation of glucose homeostasis and lipid metabolism.PMID:37707771 | DOI:10.1007/s11033-023-08726-5
Source: Molecular Biology Reports - September 14, 2023 Category: Molecular Biology Authors: Farima Kaviani Bibi Marjan Razavi Mahdieh Sadat Mohsenzadeh Maryam Rameshrad Hossein Hosseinzadeh Source Type: research
Phytochemical content, antioxidant properties, and antibacterial activities of < em > Centella asiatica < /em > L
Nat Prod Res. 2023 Sep 14:1-6. doi: 10.1080/14786419.2023.2258439. Online ahead of print.ABSTRACTThe present study is an evaluation of Centella asiatica ethanolic extract in terms of total phenolic content, total flavonoids, total flavonols, anthocyanin, antioxidants, and antibacterial activities. Centella asiatica plants were collected from Guilan province, Iran. High-performance liquid chromatography-Diode array detector analysis demonstrated that the ethanolic extract of C. asiatica contained phenolic substances such as sinapic acid, catechin, quercetin, p-coumaric acid, hesperidin, eugenol, and hesperetin. The predomin...
Source: Natural Product Research - September 14, 2023 Category: Biochemistry Authors: Marzieh Taghizadeh Shabnam Jalili Source Type: research
Can the Herbicide Dicamba Produce Oxidative Stress in the Native South American fish Jenynsia lineata at Environmentally Relevant Concentrations?
Bull Environ Contam Toxicol. 2023 Sep 14;111(3):41. doi: 10.1007/s00128-023-03796-4.ABSTRACTDicamba (DIC) is one of the most applied auxin herbicides worldwide. Sublethal effects in the South American native fish Jenynsia lineata exposed to DIC concentrations close to environmental concentrations (0.03-30 µg/L) during 48 h were analysed thorough the evaluation of catalase (CAT), glutathione S-transferase (GST), superoxide dismutase (SOD) activities and malondialdehyde (MDA) and H2O2 levels for detecting potential oxidative stress. In gills MDA increased showing oxidative damage probably because of an inefficient antioxida...
Source: Bulletin of Environmental Contamination and Toxicology - September 14, 2023 Category: Environmental Health Authors: Diana M Villagran Lucas R Lombardero Andrea C Crupkin Julieta R Mendieta Sandra K Medici Francisco Lavarello M Fernanda Simoniello Mirta L Menone Source Type: research
Nose-to-Brain Delivery of Hesperidin Nanoparticles Loaded In-Situ Gel for Neuroprotective Action
CONCLUSION: This study showed the potential of HSP NPs to be an effective neuroprotective agent.PMID:37708993 | DOI:10.1016/j.pharma.2023.09.001
Source: Annales Pharmaceutiques Francaises - September 14, 2023 Category: Drugs & Pharmacology Authors: Suraj Bamankar Vaishali Londhe Source Type: research
Bioinspired fabrication of zinc hydroxide-based nanostructure from lignocellulosic biomass Litchi chinensis leaves and its efficacy evaluation on antibacterial, antioxidant, and anticancer activity
In this study, following a low-temperature calcination process, a green synthesis of Zn-hydroxide-based nanostructure has been performed using an aqueous extract derived from the leaves of Litchi chinensis, which is employed as a lignocellulose waste biomass known to possess a variety of phytocompounds. The biogenic preparation of Zn-hydroxide based nanostructures is enabled by bioactive compounds present in the leaf extract, which act as reducing and capping agents. In order to evaluate its physicochemical characteristics, the produced Zn-hydroxide-based nanostructure has been subjected to several characterization techniq...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Manish Srivastava Kshitij R B Singh Tripti Singh Mohammed Asiri Muath Suliman Haleema Sabia Prakash Ranjan Deen Radha Chaube Jay Singh Source Type: research
Similarities and differences of nano-sized levan synthesized by Bacillus haynesii at low and high temperatures: Characterization and bioactivity
Int J Biol Macromol. 2023 Sep 12:126804. doi: 10.1016/j.ijbiomac.2023.126804. Online ahead of print.ABSTRACTLevan is a biopolymer with many different uses. Temperature is an important parameter in biopolymer synthesis. Herein, levan production was carried out from Bacillus haynesii, a thermophilic microorganism, in the temperature range of 4 °C-95 °C. The highest levan production was measured as 10.9 g/L at 37 °C. The synthesized samples were characterized by FTIR and NMR analysis. The particle size of the levan samples varied between 153 and 824.4 nm at different temperatures. In levan samples produced at high temperat...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: G özde Koşarsoy Ağçeli Source Type: research
A Nanomedicine-Enabled Ion-Exchange Strategy for Enhancing Curcumin-Based Rheumatoid Arthritis Therapy
Angew Chem Int Ed Engl. 2023 Sep 14:e202310061. doi: 10.1002/anie.202310061. Online ahead of print.ABSTRACTCurcumin (Cur) has been clinically used for rheumatoid arthritis treatment by the means of reactive oxygen species (ROS) scavenging and immune microenvironment regulation. However, this compound has a poor water solubility and moderate antioxidative activity, favoring no further broadened application. Metal complexes of curcumin such as zinc-curcumin (Zn-Cur) features enhanced water solubilities, while copper-curcumin (Cu-Cur) shows a higher antioxidant activity but lower solubility than Zn-Cur. Based on their inheren...
Source: Angewandte Chemie - September 14, 2023 Category: Chemistry Authors: Jiacai Yang Bowen Yang Jianlin Shi Source Type: research
Hormesis Defines The Limits Of Lifespan
Ageing Res Rev. 2023 Sep 12:102074. doi: 10.1016/j.arr.2023.102074. Online ahead of print.ABSTRACTThis commentary provides a novel synthesis of how biological systems adapt to a broad spectrum of environmental and age-related stresses that are underlying causes of numerous degenerative diseases and debilitating effects of aging. It proposes that the most fundamental, evolutionary-based integrative strategy to sustain and protect health is based on the concept of hormesis. This concept integrates anti-oxidant, anti-inflammatory and cellular repair responses at all levels of biological organization (i.e., cell, organ and org...
Source: Ageing Research Reviews - September 14, 2023 Category: Genetics & Stem Cells Authors: Edward J Calabrese Naomi Osakabe Rosanna Di Paola Rosalba Siracusa Roberta Fusco Ramona D'Amico Daniela Impellizzeri Salvatore Cuzzocrea Tilman Fritsch Ali S Abdelhameed Uwe Wenzel Claudio Franceschi V Calabrese Source Type: research
Anticancer Effects of Cell-Free Culture Supernatant of Escherichia coli in Bladder Cancer Cell Line: New Insight into the Regulation of Inflammation
In conclusion, our findings demonstrate that this compound is a potential candidate for the suppression of bladder cancer progression.PMID:37708921 | DOI:10.1016/j.gene.2023.147795
Source: Gene - September 14, 2023 Category: Genetics & Stem Cells Authors: Amirreza Mehmandar-Oskuie Masoud Tohidfar Bahareh Hajikhani Forouzan Karimi Source Type: research
Polyester microplastic fibers induce mitochondrial damage, apoptosis and oxidative stress in Daphnia carinata, accompanied by changes in apoptotic and ferroptosis pathway
This study imparts valuable insights into the toxicological ramifications of PET-MFs on D. carinata, underscoring their potential risks within aquatic ecosystems.PMID:37708703 | DOI:10.1016/j.aquatox.2023.106690
Source: Aquatic Toxicology - September 14, 2023 Category: Toxicology Authors: Yinan Jiang Qing Li Yuting Wang Jiaqi Jin Wenzhi Wei Yingying Zhang Hui Yang Source Type: research
Adaptive laboratory evolution empowers Chlorella vulgaris strains for sustainable lipids and biomass overproduction for environmental applications
In this report, we demonstrated the adaptive laboratory evolution (ALE) by hypersaline conditions to improve the algal strains for increasing the lipid overproduction capacity of Chlorella vulgaris for environmental applications. The evolved strains (namely E2 and E2.5) without notable impairment in general physiological parameters were scrutinized after 35 cycles. Conventional gravimetric lipidomic analysis showed that total lipid accumulation was hiked by 2.2-fold in the ALE strains compared to the parental strains. Confocal observation of algal cells stained with Nile-red showed that the abundance of lipid droplets was ...
Source: Environmental Research - September 14, 2023 Category: Environmental Health Authors: Rajendran Varunraj Uthayakumar Priyadharshini Kannusamy Vijay Srinivasan Balamurugan Source Type: research
Astaxanthin ameliorates dopaminergic neuron damage in paraquat-induced SH-SY5Y cells and mouse models of Parkinson's disease
In conclusion, our study indicates that AST had a strong protective effect on PQ-induced oxidative stress and antagonized apoptotic cell death in SH-SY5Y cells and PQ-induced mice PD model, which might provide new insights of AST for PD treatment.PMID:37708917 | DOI:10.1016/j.brainresbull.2023.110762
Source: Brain Research - September 14, 2023 Category: Neurology Authors: Lei Wang Kunliang Lu Xingyue Lou Shenghui Zhang Wenxin Song Ranran Li Lujing Geng Binfeng Cheng Source Type: research
Evaluating the ameliorative effect of nano bis-demethoxy curcumin analog against extrapulmonary toxicity in rat induced by inhaled multi-walled carbon nanotube
Environ Sci Pollut Res Int. 2023 Sep 15. doi: 10.1007/s11356-023-29749-2. Online ahead of print.ABSTRACTCarbon nanotubes (CNTs) exposure in human beings through inhalation may affect pulmonary organs and extrapulmonary organs including liver, kidney, brain, spleen, etc. The toxic effects developed as the result of CNTs exposure made us to explore the beneficial effect of nano bis-demethoxy curcumin analog (NBDMCA) towards multi-walled carbon nanotubes (MWCNTs)-induced toxicity in extrapulmonary organs. The current study described the ameliorative effect of NBDMCA against the toxic effects developed by inhaled MWCNTs in the...
Source: Environmental Science and Pollution Research International - September 14, 2023 Category: Environmental Health Authors: Arul Prakash Francis Dhanalekshmi Unnikrishnan Meenakshi Selvam Ganapathy Thiyagarajan Devasena Source Type: research
Astaxanthin ameliorates dopaminergic neuron damage in paraquat-induced SH-SY5Y cells and mouse models of Parkinson's disease
In conclusion, our study indicates that AST had a strong protective effect on PQ-induced oxidative stress and antagonized apoptotic cell death in SH-SY5Y cells and PQ-induced mice PD model, which might provide new insights of AST for PD treatment.PMID:37708917 | DOI:10.1016/j.brainresbull.2023.110762
Source: Brain Research Bulletin - September 14, 2023 Category: Neurology Authors: Lei Wang Kunliang Lu Xingyue Lou Shenghui Zhang Wenxin Song Ranran Li Lujing Geng Binfeng Cheng Source Type: research
