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Vaccination: Malaria Vaccine
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Total 1513 results found since Jan 2013.
The immunity modulation of transforming growth factor- β in malaria and other pathological process
Int Immunopharmacol. 2023 Jul 17;122:110658. doi: 10.1016/j.intimp.2023.110658. Online ahead of print.ABSTRACTThe main causative agent of malaria in humans is Plasmodium falciparum, which is spread through biting Anopheles mosquitoes. Immunoregulation in the host involving the pleiotropic cytokine transforming growth factor-β (TGF-β) has a vital role in controlling the immune response to P. falciparum infection. Based on a search of the published literature, this study investigated the correlation between malaria and immune cells, specifically the role of TGF-β in the immune response. The studies analyzed showed that, w...
Source: International Immunopharmacology - July 19, 2023 Category: Allergy & Immunology Authors: Shuang Wu Qing Nie Shuang Tan Guoyan Liao Yinyi Lv Caohua Lv Guang Chen Shuangchun Liu Source Type: research
Potential drugs in COVID-19 management
Curr Med Chem. 2023 Jul 17. doi: 10.2174/0929867331666230717154101. Online ahead of print.ABSTRACTThe SARS-CoV-2 virus first emerged in China in December 2019 and quickly spread worldwide. Despite the absence of a vaccination or authorized drug specifically developed to combat this infection, certain medications recommended for other diseases have shown potential effectiveness in treating COVID-19, although without definitive confirmation. This review aims to evaluate the existing literature on the efficacy of these medications against COVID-19. The review encompasses various potential treatments, including antiviral medic...
Source: Current Medicinal Chemistry - July 18, 2023 Category: Chemistry Authors: Amin Gasmi Sadaf Noor Alain Menzel Nataliia Khanyk Yuliya Semenova Roman Lysiuk Nataliya Beley Lidiia Bolibrukh Asma Gasmi Benahmed Olha Storchylo Geir Bj ørklund Source Type: research
Vaccination during pregnancy: A golden opportunity to embrace
Int J Gynaecol Obstet. 2023 Jul 7. doi: 10.1002/ijgo.14981. Online ahead of print.ABSTRACTImmunization strategies are part of routine pregnancy care to prevent infectious diseases in the mother, the fetus, and the newborn. Maternal immunization recommendations followed the recognition of the consequences of infectious diseases in pregnancy, including vertical transmission and perinatal consequences. The recent COVID-19 pandemic highlighted the issue of vaccination among pregnant individuals. Recommendations vary globally; however, Tdap, influenza, and, recently, COVID-19 vaccines are routinely recommended during pregnancy....
Source: Herpes - July 7, 2023 Category: Infectious Diseases Authors: Eliana Amaral Deborah Money Denise Jamieson Dharmintra Pasupathy David Aronoff Bo Jacobsson Edgar Ivan Ortiz Lizcano FIGO Committee on Infections During Pregnancy* Source Type: research
In search of a vaccine for Plasmodium vivax malaria
Nature, Published online: 28 June 2023; doi:10.1038/d41586-023-02053-2Vaccinologist Arturo Reyes-Sandoval explains how researchers are edging closer to a much-needed vaccine.
Source: Nature AOP - June 28, 2023 Category: Research Authors: Laura Vargas-Parada Source Type: research
Plasmodium knowlesi circumsporozoite protein: genetic characterisation and predicted antigenicity of the central repeat region
This study aims to characterise the CSP repeat motifs of P. knowlesi isolates in Peninsular Malaysia. CSP repeat motifs of 64 P. knowlesi isolates were identified using Rapid Automatic Detection and Alignment of Repeats (RADAR). Antigenicity of the repeat motifs and linear B cell epitopes were predicted using VaxiJen 2.0, BepiPred-2.0 and BCPred, respectively. A total of 35 dominant repeat motifs were identified. The repeat motif "AGQPQAQGDGANAGQPQAQGDGAN" has the highest repeat frequency (n=15) and antigenicity index of 1.7986. All the repeat regions were predicted as B cell epitopes. In silico approaches revealed that al...
Source: Tropical Biomedicine - June 25, 2023 Category: Tropical Medicine Authors: J H Tan F W Cheong Y L Lau M Y Fong Source Type: research
