Filtered By:
Cancer: Carcinoma
This page shows you your search results in order of date. This is page number 9.
Order by Relevance | Date
Total 97099 results found since Jan 2013.
Assessing the prognostic value of IMDC risk score for nivolumab-treated patients with renal cancer and malignant melanoma
CONCLUSION: In our study, the IMDC was confirmed to be a prognostic factor for MM. The IMDC groups were similar, except for the favorable RCC and MM groups. Different metastatic sites were prognostic, similar to the IMDC risk group in the MM group.PMID:37718781 | DOI:10.3233/CBM-230159
Source: Cancer Biomarkers : Section A of Disease Markers - September 18, 2023 Category: Cancer & Oncology Authors: Ismail Beyp ınar Y ıldız Sözel Arif Hakan Önder Source Type: research
Machine-learning based integrating bulk and single-cell RNA sequencing reveals the SLC38A5-CCL5 signaling as a promising target for clear cell renal cell carcinoma treatment
In conclusion, our communication signature and its derived model enabled a more precise selection of ccRCC patients who were potential beneficiaries of ICIs. Besides, the SLC38A5-CCL5 axis may serve as a promising target for ccRCC treatment.PMID:37722291 | DOI:10.1016/j.tranon.2023.101790
Source: Translational Oncology - September 18, 2023 Category: Cancer & Oncology Authors: Hualin Chen Wenjie Yang Lin Ma Yingjie Li Zhigang Ji Source Type: research
Association between surgical extent and recurrence in unilateral intermediate- to high-risk papillary thyroid cancer
CONCLUSION: Lobectomy alone is associated with an elevated recurrence risk in patients with unilateral intermediate- to high-risk PTC compared with larger surgical extents. However, lobectomy and ND may provide similar tumor control compared with the conventional approach of TT and ND.PMID:37723469 | DOI:10.1186/s12885-023-11307-1
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Siyuan Xu Hui Huang Huilei Dong Xiaolei Wang Zhengang Xu Shaoyan Liu Jie Liu Source Type: research
A Very Unusual Presentation of Miliary Tuberculosis and Osteomyelitis as an Incidental Finding of Musculoskeletal Pain
Cureus. 2023 Aug 27;15(8):e44207. doi: 10.7759/cureus.44207. eCollection 2023 Aug.ABSTRACTTuberculosis (TB) is a highly infectious disease that takes the primary or latent route. In primary TB, the patient often presents with constitutional symptoms such as cough, fever, weight loss, and hemoptysis. This 83-year-old patient was sent to the emergency department (ED) by her primary care physician after abnormal imaging for acute back and neck pain. Imaging revealed pulmonary TB with possible tuberculosis osteomyelitis versus metastatic carcinoma to the cervical vertebrae. The case's unique presentation gives light to the nee...
Source: Pain Physician - September 18, 2023 Category: Anesthesiology Authors: Prachi B Patel Bhavi Purohit Source Type: research
Role and clinical significance of immunogenic cell death biomarkers in chemoresistance and immunoregulation of head and neck squamous cell carcinoma
Biomed Pharmacother. 2023 Sep 16;167:115509. doi: 10.1016/j.biopha.2023.115509. Online ahead of print.ABSTRACTHead and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies in the whole world, with little improvement in the 5-year survival rate due to the occurrence of chemoresistance. With the increasing interests in tumor immune microenvironment, immunogenic cell death (ICD)-induced chemotherapy has shown promising results in enhancing sensitivity to immune checkpoint inhibitors (ICI) and improving the efficiency of tumor immunotherapy. This review summarizes the role of key ICD biomarkers and their...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 18, 2023 Category: Drugs & Pharmacology Authors: Xuanyu Zhang Chao Shang Xue Qiao Yan Guo Source Type: research
Case Report: Case Series of Kocuria palustris Bacteremia among Immunocompromised Patients
We present three cases of bacteremia in immunocompromised patients admitted to our hospital; one patient was receiving chemotherapy for gall bladder carcinoma, the second was on maintenance hemodialysis for chronic kidney disease, and the third was receiving chemotherapy for acute myeloid leukemia. All three patients presented with a fever in the setting of neutropenia during the course of treatment with chemotherapy (in Cases 1 and 3) or hemodialysis (in Case 2). The blood culture samples of all the patients had pure isolates of Kocuria species K. palustris, which was identified by matrix assisted laser desorption ionisat...
Source: The American Journal of Tropical Medicine and Hygiene - September 18, 2023 Category: Tropical Medicine Authors: Gerlin Varghese Ashima Jamwal Deepika Sarawat Chinmoy Sahu Sangram Singh Patel Nidhi Tejan Source Type: research
Breaking down tumor thrombus: Current strategies for medical management
Thromb Res. 2023 Sep 13;230:144-151. doi: 10.1016/j.thromres.2023.09.004. Online ahead of print.ABSTRACTTumor thrombus, the intravascular extension of tumor into adjacent blood vessels, is frequently encountered in patients with renal cell carcinoma and hepatocellular carcinoma, and often involves the abdominal vasculature including the renal vein, portal vein, and the inferior vena cava. While a bland thrombus is composed of platelets and fibrin, in contrast, a tumor thrombus refers to an organized collection of tumor cells. Though oftentimes detected incidentally on imaging, tumor thrombus may have significant clinical i...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Harsha Tathireddy Douglas Rice Kylee Martens Sudeep Shivakumar Joseph Shatzel Source Type: research
Case Report: Case Series of Kocuria palustris Bacteremia among Immunocompromised Patients
We present three cases of bacteremia in immunocompromised patients admitted to our hospital; one patient was receiving chemotherapy for gall bladder carcinoma, the second was on maintenance hemodialysis for chronic kidney disease, and the third was receiving chemotherapy for acute myeloid leukemia. All three patients presented with a fever in the setting of neutropenia during the course of treatment with chemotherapy (in Cases 1 and 3) or hemodialysis (in Case 2). The blood culture samples of all the patients had pure isolates of Kocuria species K. palustris, which was identified by matrix assisted laser desorption ionisat...
Source: Am J Trop Med Hyg - September 18, 2023 Category: Infectious Diseases Authors: Gerlin Varghese Ashima Jamwal Deepika Sarawat Chinmoy Sahu Sangram Singh Patel Nidhi Tejan Source Type: research
Bilateral Ovarian Metastases of Hepatocellular Carcinoma Diagnosed with < sup > 18 < /sup > F-Fluorocholine PET/CT in a Patient with Endometriosis
Nucl Med Mol Imaging. 2023 Oct;57(5):251-253. doi: 10.1007/s13139-023-00796-4. Epub 2023 Apr 14.ABSTRACTA 47-year-old woman with history of hepatocellular carcinoma was referred for 18F-fluorocholine PET/CT evaluation due to elevated alpha-fetoprotein. The examination showed several peritoneal uptakes and two nodular pelvic foci. Coelioscopic exploration allowed confirmation and resection of multiple peritoneal metastases from hepatocellular carcinoma while pelvic biopsies revealed endometriosis and endosalpingiosis. However, alpha-fetoprotein kept rising: subsequent 18F-fluorodesoxyglucose PET/CT exploration found no pelv...
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Adrien Latg é Gerlinde Averous Anne Gressel Fran çois Faitot Benjamin Leroy-Freschini Source Type: research
Development of a nomogram for predicting overall survival in patients with bladder carcinoma in situ based on SEER database analysis
Asian J Surg. 2023 Sep 16:S1015-9584(23)01447-1. doi: 10.1016/j.asjsur.2023.09.043. Online ahead of print.NO ABSTRACTPMID:37723035 | DOI:10.1016/j.asjsur.2023.09.043
Source: Asian Journal of Surgery - September 18, 2023 Category: Surgery Authors: Yi Jiang Yi Tang Qian Zhang Songwu Liang Source Type: research
Large cell neuroendocrine carcinoma of the urinary bladder: A case report and literature review
Asian J Surg. 2023 Sep 16:S1015-9584(23)01468-9. doi: 10.1016/j.asjsur.2023.09.041. Online ahead of print.NO ABSTRACTPMID:37723032 | DOI:10.1016/j.asjsur.2023.09.041
Source: Asian Journal of Surgery - September 18, 2023 Category: Surgery Authors: Peilin Xiao Jiawei Liu Wenmei Sun Jiaping Wang Source Type: research
Role of organic cation transporter 3 (OCT3) in the response of hepatocellular carcinoma to tyrosine kinase inhibitors
In conclusion, analysis by immunohistochemistry of OCT3 in the PM of tumor cells may help to predict the response of HCC patients to sorafenib and potentially to other TKIs.PMID:37722628 | DOI:10.1016/j.bcp.2023.115812
Source: Biochemical Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Elisa Herraez Ruba Al-Abdulla Meraris Soto Oscar Briz Dominik Bettinger Heike Bantel Sofia Del Carmen Maria A Serrano Andreas Geier Jose J G Marin Rocio I R Macias Source Type: research
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies
Bioorg Med Chem. 2023 Sep 7;94:117467. doi: 10.1016/j.bmc.2023.117467. Online ahead of print.ABSTRACTSulfonamides constitute an important class of classical carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. Herein we have accomplished the conjugation of biotin with an ample number of sulfonamide motifs with the aim of testing them in vitro as inhibitors of the human carbonic anhydrase (hCA) isoforms I and II (cytosolic isozymes), as well as hCA IX and XII (transmembrane, tumor-associated enzymes). Most of these newly synthesized compounds exhibited interesting inhibition profiles, with activities in the nanomolar range. The ...
Source: Bioorganic and Medicinal Chemistry - September 18, 2023 Category: Chemistry Authors: Paloma Begines Alessandro Bonardi Alessio Nocentini Paola Gratteri Simone Giovannuzzi Roberto Ronca Camilla Tavani Maria Luisa Massardi Óscar López Claudiu T Supuran Source Type: research
A nomogram based on the risk factors of cervical lymph node metastasis in papillary thyroid carcinoma coexistent with Hashimoto's thyroiditis
CONCLUSION: Based on the risk factors above, a relevant nomogram prediction model was established. The model verification showed that the C-index of the modeling set was 0.814, indicating that the nomogram model had good predicted accuracy. The nomogram based on the risk factors above had good prediction ability, which could optimize thyroidectomy and cervical lymph node dissection and improving prognosis.PMID:37718783 | DOI:10.3233/CH-221673
Source: Clinical Hemorheology and Microcirculation - September 18, 2023 Category: Hematology Authors: Huanhuan Miao Jingwen Zhong Xuesha Xing Jiawei Sun Jiaqi Wu Chengwei Wu Yan Yuan Xianli Zhou Hongbo Wang Source Type: research
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
