Fecal microbiota transplantation: current challenges and future landscapes
Clin Microbiol Rev. 2024 May 8:e0006022. doi: 10.1128/cmr.00060-22. Online ahead of print.ABSTRACTSUMMARYGiven the importance of gut microbial homeostasis in maintaining health, there has been considerable interest in developing innovative therapeutic strategies for restoring gut microbiota. One such approach, fecal microbiota transplantation (FMT), is the main "whole gut microbiome replacement" strategy and has been integrated into clinical practice guidelines for treating recurrent Clostridioides difficile infection (rCDI). Furthermore, the potential application of FMT in other indications such as inflammatory bowel dise...
Source: Clinical Microbiology Reviews - May 8, 2024 Category: Microbiology Authors: Abbas Yadegar Haggai Bar-Yoseph Tanya Marie Monaghan Sepideh Pakpour Andrea Severino Ed J Kuijper Wiep Klaas Smits Elisabeth M Terveer Sukanya Neupane Ali Nabavi-Rad Javad Sadeghi Giovanni Cammarota Gianluca Ianiro Estello Nap-Hill Dickson Leung Karen Won Source Type: research
Association of severity of menstrual dysfunction with cardiometabolic risk markers among women with polycystic ovary syndrome
ConclusionsPCOS women with amenorrhea show a higher prevalence of insulin resistance, prediabetes, and dyslipidemia compared with those with oligomenorrhea or eumenorrhea. The severity of menstrual dysfunction could be used as a readily obtainable marker for the identification of PCOS women at greatest risk of cardiometabolic diseases. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 8, 2024 Category: OBGYN Authors: Xuelan Li,
Jie Yang,
Christophe Blockeel,
Min Lin,
Xiaoyan Tian,
Haocun Wu,
Yaqi Cao,
Ling Deng,
Xianli Zhou,
Jinying Xie,
Yunzhao Hu,
Xin Chen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
miR-449a disturbs atherosclerotic plaque stability in streptozotocin and high-fat diet-induced diabetic mice by targeting CEACAM1
Emerging evidence indicates carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is involved in the development of atherosclerosis (AS). However, the roles and functions of CEACAM1 in AS remain ... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - May 8, 2024 Category: Endocrinology Authors: Jie Yu, Han Liu, Yu Chen, Ling Wang, Peng Chen, Yue Zhao, Chunxia Ou, Wei Chen, Jie Hu, Yu Wang and Yan Wang Tags: Research Source Type: research
Cardiovascular-Kidney-Metabolic Syndrome Stages in US Adults
This cross-sectional study assesses the prevalence and temporal evolution of cardiovascular-kidney-metabolic syndrome stages. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - May 8, 2024 Category: General Medicine Source Type: research
The effect of PAP on UACR and metabolic indexes in patients with MS and OSAHS
ConclusionsPAP treatment can reduce UACR in patients with MS and OSAHS, and has the effect of improving metabolic disorders. The decrease of UACR in patients may be related to the decrease of visceral fat and the improvement of insulin resistance. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 8, 2024 Category: Respiratory Medicine Source Type: research
Deep learning imaging phenotype can classify metabolic syndrome and is predictive of cardiometabolic disorders
Cardiometabolic disorders pose significant health risks globally. Metabolic syndrome, characterized by a cluster of potentially reversible metabolic abnormalities, is a known risk factor for these disorders. E... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 8, 2024 Category: Research Authors: Jacob S. Leiby, Matthew E. Lee, Manu Shivakumar, Eun Kyung Choe and Dokyoon Kim Tags: Research Source Type: research
The effect of PAP on UACR and metabolic indexes in patients with MS and OSAHS
ConclusionsPAP treatment can reduce UACR in patients with MS and OSAHS, and has the effect of improving metabolic disorders. The decrease of UACR in patients may be related to the decrease of visceral fat and the improvement of insulin resistance. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 8, 2024 Category: Respiratory Medicine Source Type: research
A proposed simplified definition of metabolic syndrome in children and adolescents: a global perspective
BMC Med. 2024 May 7;22(1):190. doi: 10.1186/s12916-024-03406-y.ABSTRACTMetabolic syndrome (MetS) is becoming prevalent in the pediatric population. The existing pediatric MetS definitions (e.g., the International Diabetes Federation (IDF) definition and the modified National Cholesterol Education Program (NCEP) definition) involve complex cut-offs, precluding fast risk assessment in clinical practice.We proposed a simplified definition for assessing MetS risk in youths aged 6-17 years, and compared its performance with two existing widely used pediatric definitions (the IDF definition, and the NCEP definition) in 10 pediat...
Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Xin'nan Zong Roya Kelishadi Hae Soon Kim Peter Schwandt Tandi E Matsha Jose G Mill Carmelo Antonio Caserta Carla Campos Muniz Medeiros Anastasios Kollias Peter H Whincup Lucia Pacifico Abel L ópez-Bermejo Min Zhao Miaobing Zheng Bo Xi Source Type: research
A proposed simplified definition of metabolic syndrome in children and adolescents: a global perspective
BMC Med. 2024 May 7;22(1):190. doi: 10.1186/s12916-024-03406-y.ABSTRACTMetabolic syndrome (MetS) is becoming prevalent in the pediatric population. The existing pediatric MetS definitions (e.g., the International Diabetes Federation (IDF) definition and the modified National Cholesterol Education Program (NCEP) definition) involve complex cut-offs, precluding fast risk assessment in clinical practice.We proposed a simplified definition for assessing MetS risk in youths aged 6-17 years, and compared its performance with two existing widely used pediatric definitions (the IDF definition, and the NCEP definition) in 10 pediat...
Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Xin'nan Zong Roya Kelishadi Hae Soon Kim Peter Schwandt Tandi E Matsha Jose G Mill Carmelo Antonio Caserta Carla Campos Muniz Medeiros Anastasios Kollias Peter H Whincup Lucia Pacifico Abel L ópez-Bermejo Min Zhao Miaobing Zheng Bo Xi Source Type: research
A proposed simplified definition of metabolic syndrome in children and adolescents: a global perspective
Metabolic syndrome (MetS) is becoming prevalent in the pediatric population. The existing pediatric MetS definitions (e.g., the International Diabetes Federation (IDF) definition and the modified National Chol... (Source: BMC Medicine)
Source: BMC Medicine - May 7, 2024 Category: Internal Medicine Authors: Xin ’nan Zong, Roya Kelishadi, Hae Soon Kim, Peter Schwandt, Tandi E. Matsha, Jose G. Mill, Carmelo Antonio Caserta, Carla Campos Muniz Medeiros, Anastasios Kollias, Peter H. Whincup, Lucia Pacifico, Abel López-Bermejo, Min Zhao, Miaobing Zheng and Bo Tags: Opinion Source Type: research
689 high fat diet induces constitutive caveolin-1-mediated lps transport in mouse jejunum with consequent metabolic syndrome
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Yasutada Akiba, Jonathan D. Kaunitz Tags: AGA Abstracts Source Type: research
Su1344 HIDDEN CELIAC AUTOIMMUNITY IS NOT ASSOCIATED WITH METABOLIC SYNDROME AND RELATED DISORDERS
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Rok Seon Choung, Eric Marietta, Alexander Lee, Katherine S. King, Joseph A. Murray Tags: AGA Abstracts Source Type: research
Tu1149 METABOLIC SYNDROME COMPONENTS AND THE RISK OF COLORECTAL CANCER IN THE APPALACHIAN POPULATION
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Shanmuga Sundaram, Usha Murughiyan, Rajan Lamichane, Alfred A. Cecchetti, Uma Sundaram Tags: AGA Abstracts Source Type: research
Tu1949 METABOLIC SYNDROME AS A MEDIATOR OF COLORECTAL CANCER RISK IN PATIENTS WITH CHRONIC HEPATITIS B INFECTION
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Mohamed K. Osman, Yong Eun, Chizoba N. Nwankwo, Obinna T. Nwankwo, Joan A. Culpepper-Morgan Tags: AGA Abstracts Source Type: research
