Filtered By:
Cancer: Skin Cancer
Nutrition: Fruit

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 149 results found since Jan 2013.

The Director of the NIH Lays Out His Vision of the Future of Medical Science
Our world has never witnessed a time of greater promise for improving human health. Many of today’s health advances have stemmed from a long arc of discovery that begins with strong, steady support for basic science. In large part because of fundamental research funded by the National Institutes of Health (NIH), which traces its roots to 1887, Americans are living longer, healthier lives. Life expectancy for a baby born in the U.S. has risen from 47 years in 1900 to more than 78 years today. Among the advances that have helped to make this possible are a 70% decline in the U.S. death rate from cardiovascular disease ...
Source: TIME: Science - October 24, 2019 Category: Science Authors: Dr. Francis S. Collins Tags: Uncategorized Healthcare medicine Source Type: news

Ambient Air Pollution and Cancer Mortality in the Cancer Prevention Study II
Conclusions: The results from this large prospective study suggest that ambient air pollution was not associated with death from most nonlung cancers, but associations with kidney, bladder, and colorectal cancer death warrant further investigation. https://doi.org/10.1289/EHP1249 Received: 18 October 2016 Revised: 31 March 2017 Accepted: 31 March 2017 Published: 21 August 2017 Address correspondence to M.C. Turner, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, 600 Peter Morand Cres., Room 216, Ottawa, Ontario, Canada K1G 3Z7. Telephone: 613-562-5381. Email: mturner@uottawa.ca Suppleme...
Source: EHP Research - August 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Rice Consumption and Squamous Cell Carcinoma of the Skin in a United States Population
Conclusion: Rice consumption may be related to the occurrence of SCC in the United States, especially among those with relatively low drinking water arsenic exposure. https://doi.org/10.1289/EHP1065 Received: 06 September 2016 Revised: 04 July 2017 Accepted: 06 July 2017 Published: 07 September 2017 Address correspondence to M.R. Karagas, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756 USA. Telephone: (603) 653-9010. Email: Margaret.R.Karagas@dartmouth.edu Supplemental Material is available online (https://doi.org/10.1289/EHP1065). The authors declare they have no actual ...
Source: EHP Research - September 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Astragalin Promotes Osteoblastic Differentiation in MC3T3-E1 Cells and Bone Formation in vivo
This study was carried out in accordance with the recommendations of the NIH guidelines for the care and use of laboratory animals. The protocol was approved by the Committees of Animal Ethics and Experimental Safety of Binzhou Medical University. Author Contributions DL supervised the whole project. LL, DW, and DL performed the major research and wrote the manuscript with equal contributions. YQ, MX, LZ, WX, XL, and LY provided technical support. SY and QZ provided their professional expertise. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financ...
Source: Frontiers in Endocrinology - April 15, 2019 Category: Endocrinology Source Type: research

Editorial: Ethnopharmacology in Central and Eastern Europe in the Context of Global Research Developments
In conclusion, this Research Topic includes a wide range of interdisciplinary research work contributing to the ultimate goals of augmenting the existing knowledge and fostering the scientific field of ethnopharmacology in Central and Eastern Europe, as well as globally. This research topic successfully gathered comprehensive interdisciplinary information in the field of ethnopharmacology from the field surveys to standardization and elucidation of molecular mechanisms of action of natural products. Moreover, with consideration of the existing challenges in the field of drug discovery form medicinal plants, this research t...
Source: Frontiers in Pharmacology - April 8, 2019 Category: Drugs & Pharmacology Source Type: research

A chemical compound from fruit extract of Juglans mandshurica inhibits melanogenesis through p-ERK-associated MITF degradation
Conclusion: A chemical constituent of Juglans mandshurica Maxim. induces an inhibitory mechanism to melanogenesis. It has the potential to become a whitening agent in the medical field, though this requires further clinical investigation.Graphical abstract
Source: Phytomedicine - December 11, 2018 Category: Drugs & Pharmacology Source Type: research

Risk factors associated with head and neck cancer in former smokers: A Brazilian multicentric study
CONCLUSION: Head and neck cancer risk in former smokers decreases after 11 years after smoking cessation, former smokers with past alcohol consumption showed an increased risk of HNC. High school level of education and moderate intake of vegetables and fruits reduced HNC risk among former smokers.PMID:35378425 | DOI:10.1016/j.canep.2022.102143
Source: Cancer Control - April 4, 2022 Category: Cancer & Oncology Authors: Luciane Campos Gislon Maria Paula Curado Rossana Ver ónica Mendoza López Jos é Carlos de Oliveira Jos é Roberto Vasconcelos de Podestá Sandra Ventorin von Zeidler Paul Brennan Luiz Paulo Kowalski Source Type: research

Research Reveals Immunotherapy More Effective in Men
For mesothelioma patients, immunotherapy is mostly available through clinical trials at this time. Immunotherapy is a relatively new way to treat cancer, and doctors still are learning who will respond best to these novel therapies. Newly released medical research has found men seem to respond better to immunotherapy than women. But this doesn’t mean immunotherapy is off the table for women with mesothelioma. You should learn all you can about how immunotherapy works, why it may or may not be right for you and how you can best prepare yourself if you decide an immunotherapy clinical trial is right for you. Thorough Revi...
Source: Asbestos and Mesothelioma News - July 3, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

Molecules, Vol. 22, Pages 2279: Labdane-Type Diterpenes, Galangalditerpenes A –C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga
Molecules, Vol. 22, Pages 2279: Labdane-Type Diterpenes, Galangalditerpenes A–C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga Molecules doi: 10.3390/molecules22122279 Authors: Yoshiaki Manse Kiyofumi Ninomiya Ryosuke Nishi Yoshinori Hashimoto Saowanee Chaipech Osamu Muraoka Toshio Morikawa In our continuing study of biologically active natural products from the fruit of Alpinia galanga (Zingiberaceae), we newly isolated three new labdane-type diterpenes, termed galangalditerpenes A–C (1–3), along with four known sesquiterpenes (4–7) and two diterpenes (8 and 9). The s...
Source: Molecules - December 20, 2017 Category: Chemistry Authors: Yoshiaki Manse Kiyofumi Ninomiya Ryosuke Nishi Yoshinori Hashimoto Saowanee Chaipech Osamu Muraoka Toshio Morikawa Tags: Article Source Type: research

Prevalence of health behaviors among cancer survivors in the United States
ConclusionsWhile the majority of cancer survivors met the guidelines for not smoking and limiting alcohol drinking, one-third had elevated BMI, almost half did not meet recommended physical activity levels, and the majority had inadequate fruit and vegetable intake.Implications for Cancer SurvivorsAdherence to guidelines was lowest among younger cancer survivors and those with lower income and education, suggesting these may be populations where resources could be targeted to have the greatest impact.
Source: Journal of Cancer Survivorship - March 18, 2023 Category: Cancer & Oncology Source Type: research

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry
Discussion Tibroviruses are highly undercharacterized rhabdoviruses with unknown pathogenic potential. All isolated tibroviruses (BAV, BHV, CPV, SWBV, and TIBV) have only been found in biting midge vectors or in various, apparently healthy non-human mammals (Cybinski et al., 1980; Standfast et al., 1984; Cybinski and Gard, 1986; Gibbs et al., 1989). The discovery of BASV, EKV-1, and EKV-2 genomes in human sera (Grard et al., 2012; Stremlau et al., 2015) suggests that at least some tibroviruses could infect humans. Because BASV was discovered in the serum of a severely ill individual, tibroviruses should be considered pote...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research

Molecules, Vol. 25, Pages 2046: Imperatorin as a Promising Chemotherapeutic Agent Against Human Larynx Cancer and Rhabdomyosarcoma Cells
ztof Polberg Adolfo Rivero-Müller Andrzej Stepulak Naturally occurring coumarins are bioactive compounds widely used in Asian traditional medicine. They have been shown to inhibit proliferation, induce apoptosis, and/or enhance the cytotoxicity of currently used drugs against a variety of cancer cell types. The aim of our study was to examine the antiproliferative activity of different linear furanocoumarins on human rhabdomyosarcoma, lung, and larynx cancer cell lines, and dissolve their cellular mechanism of action. The coumarins were isolated from fruits of Angelica archangelica L. or Pastinaca sativa L., and s...
Source: Molecules - April 27, 2020 Category: Chemistry Authors: Aneta Grabarska Krystyna Skalicka-Wo źniak Micha ł Kiełbus Magdalena Dmoszy ńska-Graniczka Paulina Miziak Justyna Szumi ło Ewa Nowosadzka Krystyna Kowalczuk Sherief Khalifa Jolanta Smok-Kalwat Janusz Klatka Krzysztof Kupisz Krzysztof Polberg Adolfo R Tags: Article Source Type: research

The Latest Breakthroughs That Could Help Bladder Cancer Patients
Toward the end of the 19th century, a New York City surgeon named Dr. William Coley purposely injected one of his patients with streptococcal bacteria. Coley wasn’t crazy. He hoped the bacterial infection would stimulate an immune response that would slow the spread of his patient’s cancer, which was inoperable. The experiment worked; the patient’s tumor shrank. For the next 40 years, Coley and his research collaborators would test similar remedies on more than 1,000 cancer patients. They had failures but also many successes, especially among people with bone or soft-tissue cancers. Today, Coley is someti...
Source: TIME: Health - July 27, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news

The Analysis of Key Factors Related to ADCs Structural Design
Conclusion and Perspective With in-depth understandings of antibodies, linkers, and payloads, ADCs have also achieved great development. The linkage strategy and target diversity have already improved the delivery of the payloads to tumor tissues and reduced exposure to normal tissues. With the development of payloads, some novel potent payloads are used by ADCs, which allows researchers to exploit novel linkers to attach the antibody and payloads without disturbing their potency (Dragovich et al., 2018). Furthermore, some irrelevant antigen-target ADCs also may exert toxicity to tumor cells due to the vascular gap of tum...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

Novel Synthesized Tyrosinase Inhibitors: A Systematic Patent Review (2012-Present)
Curr Med Chem. 2023 Feb 3. doi: 10.2174/0929867330666230203111437. Online ahead of print.ABSTRACTTyrosine is an enzyme responsible for melanin production. Its abnormal accumulation in different parts of the body is known as hyperpigmentation. Tyrosinase inhibitors have been used as one of the main approaches to treat these kinds of cosmetic and medical issues. This review aimed to discuss the advances in patents for this class of inhibitors, focusing on synthetic ones, by studying recent patent applications (2012-2022). We performed a screening using the European Patent Office's Espacenet database, from which 15 inventions...
Source: Current Medicinal Chemistry - February 6, 2023 Category: Chemistry Authors: Erika Beltran Jimenez Mairim Russo Serafini Izabel Almeida Alves Diana Marcela Arag ón Novoa Source Type: research