Research Reveals Immunotherapy More Effective in Men

For mesothelioma patients, immunotherapy is mostly available through clinical trials at this time. Immunotherapy is a relatively new way to treat cancer, and doctors still are learning who will respond best to these novel therapies. Newly released medical research has found men seem to respond better to immunotherapy than women. But this doesn’t mean immunotherapy is off the table for women with mesothelioma. You should learn all you can about how immunotherapy works, why it may or may not be right for you and how you can best prepare yourself if you decide an immunotherapy clinical trial is right for you. Thorough Review of Immunotherapy Research In June 2018, Lancet Oncology published a systematic review and meta-analysis of high-quality immunotherapy clinical trials. A systematic review answers a defined research question by carefully considering the highest quality evidence about the question of interest. In the Lancet Oncology report, the question of interest was, “Is there a difference in how well men and women with cancer respond to a type of immunotherapy known as immune checkpoint inhibitors?” A meta-analysis uses statistical methods to combine the data from the studies included in the review. By combining the studies together, researchers end up with a larger pool of people to analyze. Having a larger study sample improves a researcher’s ability to uncover differences between the groups. In the Lancet Oncology paper, the groups being compare...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news

Related Links:

Dr. Luis Diaz spoke withCancer Network about monitoring for residual disease in colon cancer ahead of his presentation at ESMO 2018.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Treatment for prostate cancer with external beam radiotherapy was found to be associated with an increased risk for development of bladder cancer when compared with radical prostatectomy.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
In his latest blog, Craig Hildreth explores the terror of the black box warning and how the fear of toxicities affects his patients —and his staff.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
This study included 240 consecutive ASD patients with a minimum of 2 years of follow-up. We calculated MCID values for total and individual ODI domains using all or part of the Scoliosis Research Society-22R questionnaire as anchors. Using current MCID values, we measured the acquisition rates in patients who acquired MCID at follow-up in both total and individual ODI domains. Differences in pathology, age, and locations of the upper and lower instrumented vertebrae were analyzed. Results: MCID of the total ODI score was 11%, with an area under the curve of 0.737. Each domain ranged from 0 to 2, with 1 being the most c...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
New test uses artificial intelligence to spot polyps, where all colorectal cancers begin. Doctors hope the technology will help save lives. CBS News' Chris Martinez reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
The ovary is surrounded by a whitish layer of mesodermally derived ovarian surface epithelium (OSE) that lines the intraembryonic celom and comprises simple squamous to cuboidal to low pseudostratified columnar epithelial cells. Its integrity is maintained by simple desmosomes, incomplete tight junctions, several integrins and cadherins. Recent research has found that ovarian stem cells (OSCs) exist within the OSE and may be responsible for both neo-oogenesis and ovarian cancer during adult life. The factors determining whether OSCs undergo neo-oogenesis or ovarian cancer are of great interest to researchers and clinicians...
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Publication date: Available online 17 October 2018Source: Neuroscience LettersAuthor(s): Benjamin Sack, Katja Broer, Silke AndersAbstractObservational and experimental studies have shown that sleep deprivation disinhibits emotional responses to disturbing and rewarding external events. On the other hand, most studies on sleep deprivation and interpersonal emotion recognition report that sensitivity to others’ emotions is dampened after sleep deprivation. This is at odds with current neuroscientific theories of social cognition that assume that affective experiences and emotion recognition in others are closely tied a...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 17 October 2018Source: NeuroImageAuthor(s): Şükrü Barış Demiral, Dardo Tomasi, Joelle Sarlls, Hedok Lee, Corinde E. Wiers, Amna Zehra, Tansha Srivastava, Kenneth Ke, Ehsan Shokri-Kojori, Clara R. Freeman, Elsa Lindgren, Veronica Ramirez, Gregg Miller, Peter Bandettini, Silvina Horovitz, Gene-Jack Wang, Helene Benveniste, Nora D. VolkowAbstractThe role of sleep in brain physiology is poorly understood. Recently rodent studies have shown that the glymphatic system clears waste products from brain more efficiently during sleep compared to wakefulness due to the expansion of the ...
Source: NeuroImage - Category: Neuroscience Source Type: research
New test uses artificial intelligence to spot polyps, where all colorectal cancers begin. CBS News' Chris Martinez reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
In this study, an accurate and sensitive surface plasmon resonance (SPR) biosensor for O-GlcNAc detection that is based on β-D-N-acetylglucosaminidase (OGA) and Au nanoparticles (AuNPs) was developed. In this strategy, AuNPs were used to amplify the SPR signal and improve the biosensor's sensitivity; OGA was used to cleave O-GlcNAc from O-GlcNAcylated biomolecules. The interaction between AuNPs labeled wheat germ agglutinin (AuNPs/WGA) and O-GlcNAcylated biomolecules on a modified Au film treated with and without OGA was recorded by SPR. The change of the SPR signal moves linearly with the amount of O-GlcNAc on the Au...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
More News: Apples | Asbestosis | Bananas | Broccoli | Cancer | Cancer & Oncology | Carcinoma | Chemotherapy | Clinical Trials | Diets | Education | Environmental Health | Fruit | Head and Neck Cancer | Immunotherapy | Kidney Cancer | Learning | Lentils | Lung Cancer | Lung Transplant | Melanoma | Mesothelioma | Non-Small Cell Lung Cancer | Nutrition | Nuts | Oatmeal | Peas | Renal Cell Carcinoma | Research | Skin Cancer | Sleep Disorders | Sleep Medicine | Statistics | Study | Sweeteners | Universities & Medical Training | Vegetables | Women | Workshops | Yervoy