The modulating effects of green rooibos ( < em > Aspalathus Linearis < /em > ) extract on vascular function and antioxidant status in obese Wistar rats
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk.PMID:33605975 | DOI:10.5830/CVJA-2020-048 (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 19, 2021 Category: Cardiology Authors: Zimvo Obasa Mignon Albertha van Vuuren Barbara Huisamen Shantal Lynn Windvogel Source Type: research

The modulating effects of green rooibos ( < em > Aspalathus Linearis < /em > ) extract on vascular function and antioxidant status in obese Wistar rats
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk.PMID:33605975 | DOI:10.5830/CVJA-2020-048 (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 19, 2021 Category: Cardiology Authors: Zimvo Obasa Mignon Albertha van Vuuren Barbara Huisamen Shantal Lynn Windvogel Source Type: research

The modulating effects of green rooibos ( < em > Aspalathus Linearis < /em > ) extract on vascular function and antioxidant status in obese Wistar rats
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk.PMID:33605975 | DOI:10.5830/CVJA-2020-048 (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 19, 2021 Category: Cardiology Authors: Zimvo Obasa Mignon Albertha van Vuuren Barbara Huisamen Shantal Lynn Windvogel Source Type: research

The modulating effects of green rooibos ( < em > Aspalathus Linearis < /em > ) extract on vascular function and antioxidant status in obese Wistar rats
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk.PMID:33605975 | DOI:10.5830/CVJA-2020-048 (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 19, 2021 Category: Cardiology Authors: Zimvo Obasa Mignon Albertha van Vuuren Barbara Huisamen Shantal Lynn Windvogel Source Type: research

The modulating effects of green rooibos ( < em > Aspalathus Linearis < /em > ) extract on vascular function and antioxidant status in obese Wistar rats
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk.PMID:33605975 | DOI:10.5830/CVJA-2020-048 (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 19, 2021 Category: Cardiology Authors: Zimvo Obasa Mignon Albertha van Vuuren Barbara Huisamen Shantal Lynn Windvogel Source Type: research

The modulating effects of green rooibos (Aspalathus Linearis) extract on vascular function and antioxidant status in obese Wistar rats.
CONCLUSIONS: Supplementation with GRT extract alleviated cardiovascular risk factors in the HFD animals, suggesting a therapeutic potential for GRT in obesity-induced cardiovascular risk. PMID: 33605975 [PubMed - as supplied by publisher] (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - February 18, 2021 Category: Cardiology Authors: Obasa Z, van Vuuren MA, Huisamen B, Windvogel SL Tags: Cardiovasc J Afr Source Type: research

Authentication of honeybush and rooibos herbal teas based on their elemental composition
Publication date: Available online 19 November 2020Source: Food ControlAuthor(s): Zuzanna Małyjurek, Beata Zawisza, Dalene de Beer, Elizabeth Joubert, Beata Walczak (Source: Food Control)
Source: Food Control - December 24, 2020 Category: Food Science Source Type: research

Cardioprotective Function of Green Rooibos (Aspalathus linearis) Extract Supplementation in Ex Vivo Ischemic Prediabetic Rat Hearts
Planta Med DOI: 10.1055/a-1239-9236Diabetic patients develop ischemic heart disease and strokes more readily. Following an ischemic event, restoration of blood flow increases oxidative stress resulting in myocardial damage, termed ischemia/reperfusion injury. Aspalathus linearis (rooibos), rich in the antioxidant phenolic compound aspalathin, has been implicated as cardioprotective against ischemia/reperfusion injury with undefined mechanism in control rats. Primarily, the therapeutic potential of Afriplex green rooibos extract to prevent ischemia/reperfusion injury in cardiovascular disease-compromised rats was investigat...
Source: Planta Medica - December 7, 2020 Category: Drugs & Pharmacology Authors: Smit, Sybrand Engelbrecht Manirafasha, Claudine Marais, Erna Johnson, Rabia Huisamen, Barbara Tags: Original Papers Source Type: research

Analysis of volatile compounds in rooibos tea (Aspalathus linearis) using different extraction methods and their relationship with human sensory perception
Publication date: Available online 4 December 2020Source: Food Research InternationalAuthor(s): Nho-Eul Song, Mina K. Kim, Kwang-Geun Lee, Hae Won Jang (Source: Food Research International)
Source: Food Research International - December 6, 2020 Category: Food Science Source Type: research

Fumonisin B1 ‐induced mitochondrial toxicity and hepatoprotective potential of rooibos: An update
AbstractFumonisins are a family of potentially carcinogenic mycotoxins produced byFusarium verticillioides. Several fumonisins have been identified with fumonisin B1 (FB1) being the most toxic. The canonical mechanism of FB1 toxicity is centered on its structural resemblance with sphinganine and consequent competitive inhibition of ceramide synthase and disruption of lipidomic profiles. Recent and emerging evidence at the molecular level has identified the disruption of mitochondria and excessive generation of toxic reactive oxygen species (ROS) as alternative/additional mechanisms of toxicity. The understanding of how the...
Source: Journal of Applied Toxicology - November 8, 2020 Category: Toxicology Authors: Naeem Sheik Abdul, Jeanine L. Marnewick Tags: HYPOTHESIS REVIEW/THEORETICAL ARTICLE Source Type: research

Buckwheat, rooibos, and vitex extracts can mitigate adverse effects of xylene on ovarian cells in vitro.
This study examines whether selected functional food and medicinal plants can mitigate the adverse effects of xylene on ovarian cells. The influences of xylene (0, 10, 100, or 1000 ng/mL), buckwheat (Fagopyrum esculentum), rooibos (Aspalathus linearis), vitex (Vitex agnus-castus), extracts (10 μg/mL each), and a combination of xylene with these plant additives on cultured porcine ovarian granulosa cells are compared. Cell viability, proliferation (PCNA accumulation), apoptosis (accumulation of bax), and release of progesterone (P4) and estradiol (E2) were analyzed by the trypan blue tests, quantitative immunocytochemist...
Source: Environmental Science and Pollution Research International - October 8, 2020 Category: Environmental Health Authors: Sirotkin AV, Macejková M, Tarko A, Fabova Z, Alwasel S, Harrath AH Tags: Environ Sci Pollut Res Int Source Type: research

Effects of hot ‑water extracts from 26 herbs on α‑glucosidase activity.
Effects of hot‑water extracts from 26 herbs on α‑glucosidase activity. Mol Med Rep. 2020 Jul 31;: Authors: Kikuchi H, Toyoda N, Ezawa S, Yoshida S, Hibino Y, Sunaga K Abstract α‑glucosidase is a key enzyme that plays a role in glucose absorption in the gastrointestinal tract, and the inhibition of its activity induces the prevention of postprandial hyperglycemia. Several α‑glucosidase inhibitors have been used as medicines for type 2 diabetes, but a similar effect is observed in natural resources, including traditional herbs and their phytochemicals. To identify the pr...
Source: Molecular Medicine Reports - September 20, 2020 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Differential Cytotoxicity of Rooibos and Green Tea Extracts against Primary Rat Hepatocytes and Human Liver and Colon Cancer Cells – Causal Role of Major Flavonoids
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - September 14, 2020 Category: Cancer & Oncology Authors: Sedicka Samodien Maryna de Kock Elizabeth Joubert Sonja Swanevelder Wentzel C. A. Gelderblom Source Type: research

Differential Cytotoxicity of Rooibos and Green Tea Extracts against Primary Rat Hepatocytes and Human Liver and Colon Cancer Cells - Causal Role of Major Flavonoids.
Abstract Differential anti-proliferative and pro-apoptotic effects of aqueous extracts of green rooibos (Rg; Aspalathus linearis) and green tea (GT; Camellia sinensis) and an aspalathin-enriched extract of green rooibos (GRE), were investigated in primary rat hepatocytes (PH) and human liver (HepG2) and colon (HT-29) cancer cells. Rooibos flavonoids, aspalathin and luteolin, and the green tea flavanol, epigallocatechin gallate (EGCG), were included to assess their contribution relative to their extract concentrations. GRE was the most effective in reducing cell growth parameters which was associated with a...
Source: Nutrition and Cancer - September 14, 2020 Category: Cancer & Oncology Authors: Samodien S, Kock M, Joubert E, Swanevelder S, Gelderblom WCA Tags: Nutr Cancer Source Type: research

Effects of benzene on gilts ovarian cell functions alone and in combination with buckwheat, rooibos, and vitex.
Abstract We aimed to examine the influence of benzene and of three dimethyl sulfoxide (DMSO) plant extracts-buckwheat (Fagopyrum Esculentum), rooibos (Aspalathus linearis), and vitex, (Vitex Agnus-Castus), and the combination of benzene with these three plant extracts on basic ovarian cell functions. Specifically, the study investigated the influence of benzene (0, 10, 100, or 1000 ng/mL) with and without these three plant additives on porcine ovarian granulosa cells cultured during 2 days with and without these additives. Cell viability, proliferation (accumulation of proliferating cell nuclear antigen, P...
Source: Environmental Science and Pollution Research International - September 10, 2020 Category: Environmental Health Authors: Sirotkin AV, Macejková M, Tarko A, Fabova Z, Alrezaki A, Alwasel S, Harrath AH Tags: Environ Sci Pollut Res Int Source Type: research