Geostatistical modelling enables efficient safety assessment for mass drug administration with ivermectin in < i > Loa loa < /i > endemic areas through a combined antibody and LoaScope testing strategy for elimination of onchocerciasis
by Olatunji Johnson, Emanuele Giorgi, Claudio Fronterr รจ, Benjamin Amoah, Julienne Atsame, Sylvie Ntsame Ella, Marco Biamonte, Kisito Ogoussan, Lee Hundley, Katherine Gass, Peter J. Diggle
The elimination of onchocerciasis through community-based Mass Drug Administration (MDA) of ivermectin (Mectizan) is hampered by co-endemicity ofLoa loa, as individuals who are highly co-infected withLoa loa parasites can suffer serious and occasionally fatal neurological reactions from the drug. The test-and-not-treat strategy of testing all individuals participating in MDA has some operational constraints including the cost and limit...
Source: PLoS Neglected Tropical Diseases - February 9, 2022 Category: Tropical Medicine Authors: Olatunji Johnson Source Type: research
Health-related quality of life and associated factors among Onchocerciasis patients in southeast Nigeria: A cross-sectional comparative study
This study assessed the HRQoL and associated factors among onchocerciasis patients in southeast Nigeria. MethodsThis was a community-based cross-sectional comparative study. Using a multistage sampling technique, 340 onchocerciasis patients were selected and matched for age and gender with the healthy population in the same neighbourhood. The respondents were interviewed using the short-form-36 (SF-36) questionnaire to determine their HRQoL. WHO Disability Assessment Schedule 2.0 tool (WHODAS 2.0) was used to assess disability in persons with onchocerciasis. Means were compared with independent student t-test while Chi-squ...
Source: PLoS Neglected Tropical Diseases - February 9, 2022 Category: Tropical Medicine Authors: Adah E. Otache Source Type: research
Community knowledge, attitudes, and practices regarding epilepsy in Mahenge, Tanzania: A socio-anthropological study in an onchocerciasis-endemic area with a high prevalence of epilepsy
CONCLUSION: Epilepsy is a major health burden and public health concern in the Mahenge area. The negative attitudes toward PWE and misconceptions about the causes of epilepsy contribute to delays in seeking care at health facilities. Findings from this study will be used to optimize the comprehensive community-based epilepsy treatment program that was recently initiated in the area.PMID:35101841 | DOI:10.1016/j.yebeh.2022.108568 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - February 1, 2022 Category: Neurology Authors: Bruno P Mmbando Dan K Bhwana Isolide S Massawe Pendo Magili Sloan Mahone Williams Makunde Adiel K Mushi Robert Colebunders Source Type: research
Community knowledge, attitudes, and practices regarding epilepsy in Mahenge, Tanzania: A socio-anthropological study in an onchocerciasis-endemic area with a high prevalence of epilepsy
CONCLUSION: Epilepsy is a major health burden and public health concern in the Mahenge area. The negative attitudes toward PWE and misconceptions about the causes of epilepsy contribute to delays in seeking care at health facilities. Findings from this study will be used to optimize the comprehensive community-based epilepsy treatment program that was recently initiated in the area.PMID:35101841 | DOI:10.1016/j.yebeh.2022.108568 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - February 1, 2022 Category: Neurology Authors: Bruno P Mmbando Dan K Bhwana Isolide S Massawe Pendo Magili Sloan Mahone Williams Makunde Adiel K Mushi Robert Colebunders Source Type: research
Community knowledge, attitudes, and practices regarding epilepsy in Mahenge, Tanzania: A socio-anthropological study in an onchocerciasis-endemic area with a high prevalence of epilepsy
CONCLUSION: Epilepsy is a major health burden and public health concern in the Mahenge area. The negative attitudes toward PWE and misconceptions about the causes of epilepsy contribute to delays in seeking care at health facilities. Findings from this study will be used to optimize the comprehensive community-based epilepsy treatment program that was recently initiated in the area.PMID:35101841 | DOI:10.1016/j.yebeh.2022.108568 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - February 1, 2022 Category: Neurology Authors: Bruno P Mmbando Dan K Bhwana Isolide S Massawe Pendo Magili Sloan Mahone Williams Makunde Adiel K Mushi Robert Colebunders Source Type: research
