Welcoming Bioelectronic Medicine
Valentin A. Pavlov, Managing Editor and Margot Puerta, Executive Editor Can you tell us a bit more about the aims and history of Bioelectronic Medicine? The field of bioelectronic medicine comprises basic research identifying the mechanisms of neural regulation and their translation into new treatments for many diseases and conditions, such as rheumatoid arthritis, diabetes, and paralyses. The first successful examples of this translational approach are the recent clinical trials with vagus nerve stimulation in patients with rheumatoid arthritis and inflammatory bowel disease. The team-based efforts of immunologists, neur...
Source: BioMed Central Blog - March 15, 2018 Category: General Medicine Authors: Alice Ridgway Tags: Open Access Publishing Bioelectronic Medicine Source Type: blogs

3D-printed Microfluidic Device for Point-of-Care Single-Cell Analysis
Researchers at the New York Genome Center and New York University have developed a portable low-cost analysis device that can perform single-cell RNA sequencing. The researchers hope that the device will enable genetic sequencing at the bed-side to help identify cell types that can be targeted using specific drugs, and the device also has potential for basic research applications. Single-cell sequencing holds enormous promise in helping researchers to understand disease and identify new and optimal treatments. However, at present, the technique typically requires expensive equipment that can be difficult to use. To address...
Source: Medgadget - February 27, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Source Type: blogs

Can the Scorpion ’s Venom Used as a Medicine to Cure Rheumatoid Arthritis?
Rheumatoid Arthritis is an autoimmune disease where the body attacks its own dense mechanism. Rheumatoid arthritis affects the joints, causing pain, sensitiveness, inflammation and immobility. A team of scientists in the past have identified a potassium channel on cells called fibroblast — like synoviocytes (FLS) in patients with rheumatoid arthritis, responsible for the development of the disease. The researchers are keen in finding a way to block the channel to stop the cells damaging the joints. A particular element called iberiotoxin, which is capable of blocking the FLS potassium channel and reduce the severit...
Source: Sciences Blog - February 27, 2018 Category: Science Authors: srinivas_s at omicsgroup.co.in (OMICS Publishing Group) Tags: Orthopedics & Rheumatology Rheumatology: Current Research journal of rheumatology open access rheumatology journals rheumatology impact factor list rheumatology research journals rheumatology research papers Source Type: blogs

Evidence for Senescent T-Cells to Promote Bone Loss, a Phenomenon Accelerated in Rheumatoid Arthritis Patients
Senescent cells cause harm throughout the body, accumulating in number with advancing age. They are found in all tissues, and this includes the cells of the immune system. The growing presence of senescent cells, and the harmful signals they generate, is one of the root causes of degenerative aging. There is a good amount of evidence for senescent cells to contribute to osteoporosis, of which the most compelling is that osteoporosis can be partially reversed in mice through targeted clearance of these unwanted cells. The study here is a different view into the link between cellular senescence and bone loss, with a focus on...
Source: Fight Aging! - February 26, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Dr. Google: The top 10 health searches in 2017
Follow me on Twitter @RobShmerling Ever wonder what other people are wondering about? I know I do. So, here are the top 10 health searches in Google for 2017. And just so you don’t have to look each one up, I’ve provided a brief answer. You’re welcome. 1.  What causes hiccups? I was surprised this one made it to the top 10 list of health searches. Maybe this search is common because hiccups are as mysterious as they are universal. I’ve written about hiccups before, but let’s just say the cause in any individual person is rarely known or knowable. Then again, the reason hiccups stop is also unknown. Some triggers...
Source: Harvard Health Blog - February 21, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Source Type: blogs

Overloaded with Instructions
I get it. I have a lot of ailments so I am in a lot of groups and follow a lot of organizations for their health tips. So I get lots of email. Tons of email to be precise. Some of it gets the delete button right away - especially if the subject line doesn ' t tell me anything.But then Iread glance at a lot of them before deleting. But often they provide suggestions or instructions how to be healthier for whichever ailment. But now I am overloaded with instructions/suggestions this week:No more asparagus for me because itcan lead to breast cancer spread. I like asparagus. Damn.Exercise can reducebreast cancer recurrence. I ...
Source: Caroline's Breast Cancer Blog - February 8, 2018 Category: Cancer & Oncology Tags: breast cancer confusion fibromyalgia instructions rheumatoid arthritis Source Type: blogs

A Useless'Perk' from My Health Insurance
I have found them most useless perk from any health insurance plan ever. When I was diagnosed with RA, my health insurance informed me that I was eligible for this perk called the Accordant Care in.What this plan includes is a quarterly conversation with a nurse on current medications and any recent heath issues I might have had as well as a monthly newsletter with health tips. The nurse is also available at other times if I have questions on any health issues.That all sounds good, right? Wrong.Every conversation with the nurse consisted of them reading me scripted questions that I had to answer: have I fallen in the last ...
Source: Caroline's Breast Cancer Blog - February 1, 2018 Category: Cancer & Oncology Tags: caregiving idiots rheumatoid arthritis Source Type: blogs

The Opioid Crisis – In Your Cupboard
The opioid epidemic of the last 20 years has served to illustrate the powerful addictive properties of anything that binds to opioid receptors of the human brain. Lives are ruined by opioid addiction, more than 100 deaths now occurring every day from overdose as people either take more and more to overcome the partial tolerance or new potent drugs like fentanyl make their way into street versions. Drugs such as oxycodone, hydrocodone, and fentanyl bind to the brain’s opioid receptors provoking a “high” while causing the user to desire more opioids as partial tolerance develops. And make no mistake: Much o...
Source: Wheat Belly Blog - January 30, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle addiction addictive eating disorder opiates opioids undoctored Source Type: blogs

Fight Aging! Newsletter, January 29th 2018
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities. Delivery of Extracellular Vesicles as a Potential Basis for Therapies https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/ Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harvest...
Source: Fight Aging! - January 28, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Old-Fashioned Approach to Delivery and Targeting of Gene Therapy for Arthritis
Sometimes the old-fashioned, simple solution is more than sufficient for the task at hand. In today's open access review paper, researchers discuss the delivery and targeting of gene therapies to arthritic joint tissue via the simple expedient of injecting the therapeutic into the joint - the most modern of medical treatments married to a 150-year-old technology. And why not? The alternatives for targeting a therapy to a specific tissue are numerous, but all quite complicated and expensive: magnetic fields to guide metallic nanoparticles attached to the therapeutic; using seeker proteins that preferentially match the surfa...
Source: Fight Aging! - January 22, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

7 Reasons To Meditate
You're reading 7 Reasons To Meditate, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Do you always feel tired, stressed, and angry? Are you impulsive and can`t seem to stop snapping at people for the wrong reasons? If you say Yes, then you have to meditate more often. Why You Must Meditate Meditation is one of the best physical and spiritual activities you can gift yourself. For just 10 minutes each day, you can improve your mood, boost your energy and increase tranquility. But it`s not just about that. Researchers have ...
Source: PickTheBrain | Motivation and Self Improvement - January 22, 2018 Category: Consumer Health News Authors: Marwan Jamal Tags: featured health and fitness psychology self improvement alzheimer's health benefits of meditation meditate pickthebrain sleep aid Source Type: blogs

Until I Drop
Every day that I go out the door (which is not everyday), I go until I drop or that is what it feels like.Yesterday is an example: three doctor appointments at two different places 45 minutes apart, two stops at stores, one stop at my parents for 15 minutes, and then home. I was so tired by the time I got home, I was barely standing. I took the easy way out and got in bed for the next two hours.At my last stop, at the podiatrist that I have been going to since last summer, I ran into a friend who worked there. I knew she worked in a medical office but I didn ' t know she worked in that one. She only works two days a week w...
Source: Caroline's Breast Cancer Blog - January 9, 2018 Category: Cancer & Oncology Tags: fatigue fibromyalgia naps rheumatoid arthritis tired Source Type: blogs

Simple Assessments of Resilience as Potential Biomarkers of Aging
The search for low-cost, reliable measures of biological age continues apace in the research community. The more the better. Even if an individual measure is only loosely correlated, or produces fairly fuzzy, variable data, it may be still be possible to build an algorithm that combines many such different measures into a more accurate overall biomarker of aging. Given such a biomarker, the research community could more rapidly explore and assess potential rejuvenation therapies, and progress in the field of longevity science would accelerate as a result. Physical resilience is the ability of an organism to respon...
Source: Fight Aging! - January 9, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Does Pregnancy Alter the Brain ’ s Immune Function?
Recent research published in the November 2017 issue of Brain, Behavior, and Immunity suggests that a woman’s immune response in the brain may decrease during pregnancy and the postpartum period. These findings, discussed by the Brain and Behavior Research Foundation, might help to establish a connection between the brain’s immune function and the anxiety and mood disorders that are common throughout pregnancy and the postpartum period. Previous research has shown that during pregnancy, the response of the body’s peripheral immune system (the part of our protective system that does not protect the brain) is suppress...
Source: World of Psychology - December 19, 2017 Category: Psychiatry & Psychology Authors: Janet Singer Tags: Brain and Behavior General Grief and Loss Health-related Mental Health and Wellness Research Women's Issues Bipolar Depression fetal development immune changes Immune Function Immunity immunosuppression Mania miscarriage Moth Source Type: blogs