The Future of 3D Printing Drugs In Pharmacies Is Closer Than You Think
3D printing drugs is not a fantasy anymore. Unbelievable shapes and any kind of drug can be fabricated with groundbreaking technology. The UK biotech company, FabRx believes it could even appear as a regular technique in hospitals and pharmacies for creating personalised drugs in specific doses within 5-10 years. In February 2022 the company announced they developed a technology allowing them to 3D print tablets in 7-17 seconds, a huge improvement from earlier.
Print out starfish-shaped drugs for your child at home
Somewhere in the 2030s: Annie was called by her daughter’s teacher that she had a high fever...
Source: The Medical Futurist - August 9, 2022 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Future of Medicine Future of Pharma Healthcare Innovation Personalized medicine GC1 pharmacies 3d printed drugs personalized drugs Source Type: blogs
TORdx LUNG Test for Donor Lung Assessment: Interview with Eric Brouwer, Chief Scientific Officer at SQI Diagnostics
SQI Diagnostics, a medtech company based in Canada, is developing the TORdx LUNG Test. The technology is intended to assist clinicians in assessing donor lungs in their suitability for transplantation. At present, clinicians typically assess donor lungs using qualitative variables, such as donor health and lung size. One of the most important factors, lung inflammation, is difficult to assess, and clinicians will often play it safe and reject an organ if there is any doubt about it.
This means that lungs that might actually be suitable for transplantation are often rejected, further compounding the lack of donor organs....
Source: Medgadget - July 18, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Exclusive Medicine Thoracic Surgery lung transplant sqi diagnostics Source Type: blogs
Caregivers Can Troubleshoot and Empathize Without “Fixing” Everything
Photo credit Andrea Picquadio
Dear Carol: My mom, now 87, voluntarily moved to assisted living three years ago. She said at the time that she loved it. She continues to have chronic pain from rheumatoid arthritis and takes medications for the usual age-related issues. Even though she forgets things more often than she used to, she doesn’t seem to have dementia. Lately, though, she’s started complaining about being “forced” to move to “this place,” saying that she hates it. Of course, she likes some caregivers better than others, but nothing major seems to have changed regarding her care. I visit several t...
Source: Minding Our Elders - July 3, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article.
It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs
Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
ASC Specks as a Sizable Contribution to Chronic Inflammation
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - April 26, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Towards Control of Inflammation as an Important Goal in the Treatment of Aging
Today I'll point out a review article that laments the present state of progress towards the control of inflammation in the human body. While acknowledging that great strides have been made in ways to interfere in inflammatory signaling, benefiting many patients, present tools are crude in comparison to the technologies that will most likely be needed in order to truly control unresolved, chronic inflammation and eliminate its contribution to age-related disease. True control of inflammation would imply the ability to (a) trigger resolution mechanisms with specificity, avoiding impairment of the operation of inflammation w...
Source: Fight Aging! - April 25, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Discovering What's Behind Older Adults' Fear of Falling May Encourage More Activity
Photo credit Jonas Kakaroto
Dear Carol: My mother lives with pain from rheumatoid arthritis and she’s also experiencing early symptoms of Alzheimer’s. She’s used a cane for years and was confident with these aids but recently she’s become terrified of falling. I bought her a walker, and she says that makes her feel more stable. Still, she’s fearful when she moves around so she’s become extraordinarily sedentary. I can understand caution, but I’m afraid that if she avoids all activity, her health will decline even faster. She lives with me and there can be friction when I make suggestions. Is ther...
Source: Minding Our Elders - April 3, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Whither Covid?
I recommend this Twitter thread by John Burn-Murdoch, as most Americans and their political leaders have apparently decided that the pandemic is over. It isn ' t, although here in the U.S. we are in a better place than we were a year ago. In a nutshell, new cases and hospitalizations are rising in much of the world, including much of Europe. This isn ' t so much because of loosened mitigation measures, but because of the emergence of a new variant, Omicron B.A2 which is evidently even more contagious than the original Omicron and perhaps a bit better at getting around existing immunity. It ' s just starting to show up...
Source: Stayin' Alive - March 18, 2022 Category: American Health Source Type: blogs
Notes and Cards Can Help People Living with Dementia Remember Visits
Photo credit Fred Kearney
Dear Carol: My father moved into assisted living several years ago because of his rheumatoid arthritis. A few months back, he was diagnosed with Alzheimer’s so now he’s been moved into their memory care wing. Both of Dad’s parents developed Alzheimer’s so he’s become quite depressed thinking he’ll follow the same path they did. Unfortunately, he seems to be losing ground with his memory very quickly so even though I drive into town every weekend to see him he forgets my visits. He can still read though he can’t remember well enough to read books or articles. Do you think it wo...
Source: Minding Our Elders - February 6, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Top 10 Digital Health News Of 2021
From the approval of a new prescription VR treatment to renewed privacy concerns, 2021 has been full of digital health developments. Indeed, some news might have gone under the radar or might require a quick refresher; so we’re wrapping up 2021 with a round-up of 10 of the most important digital health news of this year.
1. FDA-approved prescription VR treatment for chronic back pain
In mid-November, the FDA authorised a virtual reality (VR) system as a prescription treatment for chronic back pain. Called EaseVRx, it combines cognitive behaviour therapy techniques and breathing exercises to help relax, distract...
Source: The Medical Futurist - December 16, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Covid-19 3D Printing Health Sensors & Trackers Portable Medical Diagnostics Security & Privacy Telemedicine & Smartphones apple telehealth blood pressure A.I. 23andme news remote care 2021 Source Type: blogs
Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated.
Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity
Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Tips for Traveling with Mobility Limitations Along with Incontinence
Traveling with conditions like multiple sclerosis (MS) or rheumatoid arthritis (RA) can be challenging, particularly when mobility is a serious concern. Add incontinence to that - something that is quite common with MS - and the challenge increases. Yet, it can be done. It takes research and careful planning like this couple did but they made it work last summer. Start planning your trip for spring!
Read more about traveling with extra challenges like incontinence on Egosancares blog:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpos...
Source: Minding Our Elders - December 3, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Results from a Trial of the Senolytic Fisetin in a Single Individual with Autoimmunity
Today's materials from the Intraclear Biologics team may be of interest to those following the development of senolytic therapies. Since the Mayo Clinic has yet to publish results from their clinical trials of fisetin as a senolytic therapy, and may not do so for a few years yet, it is good to see even preliminary data from other sources. Senolytic therapies selectively destroy senescent cells, though only one approach (the combination of dasatinib and quercetin) has been definitely shown to destroy significant numbers of senescent cells in humans. Data has yet to be published on whether fisetin performs as well in humans ...
Source: Fight Aging! - November 30, 2021 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
Fight Aging! Newsletter, November 29th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - November 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
