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Chronic cough in adult patients-evidence-based approach
HNO. 2024 Feb 6. doi: 10.1007/s00106-023-01412-9. Online ahead of print.ABSTRACTApproximately 10% of the population suffer from a cough lasting longer than 8 weeks. Compared to acute cough, which usually occurs in the context of banal respiratory tract infections, the differential diagnoses of chronic cough require an increased use of diagnostic tests and thus a structured, evidence-based approach according to current international guidelines. A targeted history (smoking status, medication, previous diseases) and ENT status are always followed by chest x‑ray and pulmonary function tests before extended diagnostics. In th...
Source: HNO - February 6, 2024 Category: ENT & OMF Authors: Karen Kr üger Felix Holzinger Source Type: research

Impact of continuous care on cardiac function in patients with lung cancer complicated by coronary heart disease
CONCLUSION: After undergoing PCI, lung patients with CHD could benefit from continued care in terms of cardiac and pulmonary function, medications compliance, and quality of life.PMID:38313633 | PMC:PMC10835687 | DOI:10.12998/wjcc.v12.i2.314 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - February 5, 2024 Category: Cancer & Oncology Authors: Ting Gao Jin-Lan Luo Pan Guo Xi-Wen Hu Xiao-Yan Wei Yan Hu Source Type: research

Effect of lung rehabilitation training combined with nutritional intervention on patients after thoracoscopic resection of lung cancer
In conclusion, lung rehabilitation training combined with nutritional intervention can promote the postoperative rehabilitation of patients with lung cancer. The research has been duly registered in the Chinese Clinical Trial Register platform (registration no. ChiCTR2300078681; registered Dec 15, 2023).PMID:38312912 | PMC:PMC10835337 | DOI:10.3892/ol.2024.14251 (Source: Oncology Letters)
Source: Oncology Letters - February 5, 2024 Category: Cancer & Oncology Authors: Jianjun Li Jing Zheng Source Type: research

Analysis of preoperative and postoperative blood gas indices and airflow dynamics with tracheal stenosis undergoing tracheal reconstruction
The objective of the study was to investigate the impact of tracheal reconstruction in cases of tracheal stenosis on blood gas indices as well as airflow indices and whether arterial blood gas (ABG) can be a better surrogate of adequacy of tracheal reconstructi on. This was a retrospective observational study of 61 patients with tracheal stenosis between the ages of 21 and 65 years who underwent tracheal reconstruction. The preoperative and postoperative values of various blood gas indices like partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2), and potential of hydrogen (pH) and airflow indices l...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - February 5, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Association of firefighting exposures with lung function using a novel job exposure matrix (JEM)
Discussion Smoke particle exposures were observed to have modest short-term and long-term associations with pulmonary function, particularly in those who, previously, had high levels of WTC exposure. Future work examining the association between P and pulmonary function among non-WTC exposed firefighters will be essential for disentangling the effects of ageing, routine firefighting and WTC exposures. (Source: Occupational and Environmental Medicine)
Source: Occupational and Environmental Medicine - February 2, 2024 Category: Occupational Health Authors: Goldfarb, D. G., Prezant, D. J., Zeig-Owens, R., Hall, C. B., Schwartz, T., Liu, Y., Kavouras, I. G. Tags: Workplace Source Type: research

Personalized pulmonary rehabilitation program for patients with post ‐acute sequelae of COVID‐19: A proof‐of‐concept retrospective study
AbstractLong-COVID patients present with a decline in physical fitness. The aim of this study is to reveal the impact of pulmonary rehabilitation (PR) on physical fitness, quality of life (QoL), and parameters of quantified thorax CT. Long-COVID patients enrolled in a 3-month PR program were retrospectively studied. PR included endurance and resistance training three times a week. Assessments pre- and post-rehabilitation included quantified chest CT, pulmonary function tests (PFT), six-minute walk test (6MWT), cardiopulmonary exercise test, and questionnaires: Hospital Anxiety and Depression Scale, post-COVID-19 Functional...
Source: Physiological Reports - February 1, 2024 Category: Physiology Authors: Wendel Dierckx, Wilfried De  Backer, Yinka De Meyer, Eline Lauwers, Erik Franck, Jan De Backer, Kris Ides Tags: ORIGINAL ARTICLE Source Type: research

Reconciling the past and considering the future of pulmonary function test interpretation
Extract In 2023, the American Thoracic Society (ATS) published a research statement that called for the discontinuation of race- or ethnicity-based interpretation of pulmonary function tests [1]. After decades of recommendations to use specific reference equations developed for people of different ancestral origins [2–4], many people in the respiratory community, especially outside of the USA, are confused about what to do in their daily practice. (Source: European Respiratory Journal)
Source: European Respiratory Journal - February 1, 2024 Category: Respiratory Medicine Authors: Dinh-Xuan, A. T., Graham, B. L., Thompson, B., Miller, M. R., Stanojevic, S. Tags: Editorials Source Type: research

Enhancing Appropriateness of Lung Function Test Orders: Beyond Electronic Medical Record Modifications
This study focuses on non-respiratory providers ordering specialized testing (bronchoprovocation and neuromuscular testing). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Amogh Nadkarni, Brent Kaufmann Source Type: research

Early-life Pulmonary Viral Infection Leads to Long-term Functional and lower airway Structural changes in the lungs
Am J Physiol Lung Cell Mol Physiol. 2024 Jan 30. doi: 10.1152/ajplung.00300.2023. Online ahead of print.ABSTRACTEarly-life respiratory virus infections have been correlated with enhanced development of childhood asthma. In particular, significant numbers of RSV-hospitalized infants go on to develop lung disease. It has been suggested that early-life viral infections may lead to altered lung development or repair that negatively impacts lung function later in life. Our data demonstrate that early-life RSV infection modifies lung structure, leading to decreased lung function. At 5 weeks post-neonatal RSV infection, significa...
Source: Am J Physiol Lung Ce... - January 30, 2024 Category: Respiratory Medicine Authors: Carrie-Anne Malinczak Wendy Fonseca Steven M Hrycaj Susan B Morris Andrew J Rasky Kazuma Yagi Deneen M Wellik Steven F Ziegler Rachel L Zemans Nicholas W Lukacs Source Type: research

Early-life Pulmonary Viral Infection Leads to Long-term Functional and lower airway Structural changes in the lungs
Am J Physiol Lung Cell Mol Physiol. 2024 Jan 30. doi: 10.1152/ajplung.00300.2023. Online ahead of print.ABSTRACTEarly-life respiratory virus infections have been correlated with enhanced development of childhood asthma. In particular, significant numbers of RSV-hospitalized infants go on to develop lung disease. It has been suggested that early-life viral infections may lead to altered lung development or repair that negatively impacts lung function later in life. Our data demonstrate that early-life RSV infection modifies lung structure, leading to decreased lung function. At 5 weeks post-neonatal RSV infection, significa...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - January 30, 2024 Category: Cytology Authors: Carrie-Anne Malinczak Wendy Fonseca Steven M Hrycaj Susan B Morris Andrew J Rasky Kazuma Yagi Deneen M Wellik Steven F Ziegler Rachel L Zemans Nicholas W Lukacs Source Type: research

Factors influencing long-term outcomes in fibrotic interstitial lung disease (F-ILD) diagnosed through multidisciplinary discussion (MDD): a prospective cohort study
ConclusionThe long-term mortality rate of IPF patients was higher than that of CTD-ILD patients. The GAP score and UIP patterns were significant mortality predictors for both IPF and CTD-ILD patients. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - January 30, 2024 Category: Research Source Type: research