BET 1: Metoclopramide or prochlorperazine for headache in acute migraine?
A short-cut review was carried out to determine whether metoclopramide or prochlorperazine was better at relieving headache in patients attending the emergency department with acute migraine. Eighty-one papers were found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of those best papers are shown in table 1. It is concluded that in adult patients presenting to the emergency department with acute migraine, prochlorperazine 10 mg is bet...
Source: Emergency Medicine Journal - June 13, 2013 Category: Emergency Medicine Tags: EMJ Best evidence topic reports, Headache (including migraine), Pain (neurology) Source Type: research
Clinical Reasoning: A 44-year-old woman with headache followed by sudden neurologic decline
A 44-year-old woman with a history of migraines and idiopathic intracranial hypertension presented to the emergency room with 1 day of headache and nausea. She had been otherwise healthy with no sick contacts. She was afebrile without nuchal rigidity, rash, or cardiac murmur, and her neurologic examination was normal. Migraine therapy was initiated with IV prochlorperazine, ketorolac, and magnesium. Two hours later, she developed fever (101.4°F) and confusion, continually stating, "It hurts," but unable to answer questions or follow commands despite an otherwise unremarkable examination. Noncontrast head CT demonstrate...
Source: Neurology - March 25, 2013 Category: Neurology Authors: Berkowitz, A. L., Kimchi, E. Y., Hwang, D. Y., Vaitkevicius, H., Henderson, G. V., Feske, S. K., Chou, S. H.- Y. Tags: Hydrocephalus, Stroke in young adults, Meningitis, Critical care RESIDENT AND FELLOW SECTION Source Type: research
Medicinal Use of Marijuana.
Authors:
Abstract
Case Vignette Marilyn is a 68-year-old woman with breast cancer metastatic to the lungs and the thoracic and lumbar spine. She is currently undergoing chemotherapy with doxorubicin. She reports having very low energy, minimal appetite, and substantial pain in her thoracic and lumbar spine. For relief of nausea, she has taken ondansetron and prochlorperazine, with minimal success. She has been taking 1000 mg of acetaminophen every 8 hours for the pain. Sometimes at night she takes 5 mg or 10 mg of oxycodone to help provide pain relief. During a visit with her primary care physician she a...
Source: Pain Physician - February 20, 2013 Category: Anesthesiology Tags: N Engl J Med Source Type: research
Effectiveness of Standardized Combination Therapy for Migraine Treatment in the Pediatric Emergency Department
ConclusionStandardized combination therapy is effective for acute pediatric migraine therapy in the ED by significantly reducing headache pain scores, length of ED stay, and hospital admission rates. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - February 13, 2013 Category: Neurology Authors: Stephanie Leung, Blake Bulloch, Christine Young, Marcy Yonker, Mark Hostetler Tags: Research Submission Source Type: research
Effectiveness of Standardized Combination Therapy for Migraine Treatment in the Pediatric Emergency Department.
CONCLUSION: Standardized combination therapy is effective for acute pediatric migraine therapy in the ED by significantly reducing headache pain scores, length of ED stay, and hospital admission rates.
PMID: 23406529 [PubMed - as supplied by publisher] (Source: Headache)
Source: Headache - February 13, 2013 Category: Neurology Authors: Leung S, Bulloch B, Young C, Yonker M, Hostetler M Tags: Headache Source Type: research
Commonly Prescribed Medications in a Population of Hospice Patients.
Abstract
Although much attention has been placed on appropriate symptom management at the end of life, little is known about the medications actually prescribed to people in hospice care. The purpose of this study was to determine the most commonly prescribed medications in a population of hospice patients. A retrospective review of a patient information database was conducted. The 6 most common drugs (acetaminophen, morphine, haloperidol, lorazepam, prochlorperazine, and atropine) were included in emergency kits provided to patients at admission. Opioid and nonopioid analgesics, anxiolytics, anticholinerg...
Source: The American Journal of Hospice and Palliative Care - February 12, 2013 Category: Palliative Care Authors: Sera L, McPherson ML, Holmes HM Tags: Am J Hosp Palliat Care Source Type: research
