Serotonin Syndrome After Treatment of Nausea and Vomiting in Pregnancy
CONCLUSION: Serotonin syndrome is a serious clinical entity that can be provoked by the pharmacotherapy given to treat nausea and vomiting in pregnancy. This medical emergency requires early recognition and prompt management.PMID:36075069 | DOI:10.1097/AOG.0000000000004941 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - September 8, 2022 Category: OBGYN Authors: Daniel Wiseman Gordan Samoukovic Liam Durcan Isabelle Malham é Source Type: research
Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization
AAPS PharmSciTech. 2022 Jun 2;23(5):156. doi: 10.1208/s12249-022-02307-8.ABSTRACTSumatriptan succinate and prochlorperazine maleate are a clinically proven combination for treating migraine and associated nausea and vomiting. Classical oral dosage forms are not frequently workable in migraine because of the associated nausea/vomiting, and no effective fixed dose combination is available. Thus, the aim of the study was to optimize a combined sumatriptan-prochlorperazine orodispersible film for rapid release of drugs. Orodispersible films were prepared by solvent casting method using varied amounts of polyvinyl alcohol and g...
Source: AAPS PharmSciTech - June 2, 2022 Category: Drugs & Pharmacology Authors: Sana Javed Amjad Hussain Pervaiz Akhtar Shah Syed Atif Raza Ubaid Ullah Anwer Rahat Shamim Fatima Rasool Muhammad Ahsan Hafiz Nadeem Irfan Bukhari Source Type: research
Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization
AAPS PharmSciTech. 2022 Jun 2;23(5):156. doi: 10.1208/s12249-022-02307-8.ABSTRACTSumatriptan succinate and prochlorperazine maleate are a clinically proven combination for treating migraine and associated nausea and vomiting. Classical oral dosage forms are not frequently workable in migraine because of the associated nausea/vomiting, and no effective fixed dose combination is available. Thus, the aim of the study was to optimize a combined sumatriptan-prochlorperazine orodispersible film for rapid release of drugs. Orodispersible films were prepared by solvent casting method using varied amounts of polyvinyl alcohol and g...
Source: AAPS PharmSciTech - June 2, 2022 Category: Drugs & Pharmacology Authors: Sana Javed Amjad Hussain Pervaiz Akhtar Shah Syed Atif Raza Ubaid Ullah Anwer Rahat Shamim Fatima Rasool Muhammad Ahsan Hafiz Nadeem Irfan Bukhari Source Type: research
