ChemoPROphyLaxIs with hydroxychloroquine For covId-19 infeCtious disease (PROLIFIC) to prevent covid-19 infection in frontline healthcare workers: A structured summary of a study protocol for a randomised controlled trial
AbstractObjectivesPrimary objectiveTo determine whether chemoprophylaxis with hydroxychloroquine versus placebo increases time to contracting coronavirus disease 2019 (COVID-19) in frontline healthcare workers.Secondary objectivesTo determine whether chemoprophylaxis with daily versus weekly dosing of hydroxychloroquine increases time to contracting COVID-19 disease in frontline healthcare workers.To compare the number of COVID-19 cases between each trial arm on the basis of positive tests (as per current clinical testing methods and/or serology)To compare the percentage of COVID-19 positive individuals with current testin...
Source: Trials - July 2, 2020 Category: Research Source Type: clinical trials

Paracervical Injection for Headache in the Emergency Department
Conditions:   Headache Disorders, Primary;   Pain Management;   Emergency Department Interventions:   Drug: Paracervical injection;   Drug: prochlorperazine and diphenhydramine.(Standard Treatment) Sponsor:   Christian Fromm, MD Not yet recruiting (Source:
Source: - October 1, 2019 Category: Research Source Type: clinical trials

Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
Condition:   Breast Carcinoma Interventions:   Drug: Dexamethasone;   Other: Laboratory Biomarker Analysis;   Drug: Netupitant/Palonosetron Hydrochloride;   Drug: Olanzapine;   Other: Placebo;   Drug: Prochlorperazine;   Other: Quality-of-Life Assessment Sponsors:   Gary Morrow;   National Cancer Institute (NCI) Not yet recruiting (Source:
Source: - December 8, 2017 Category: Research Source Type: clinical trials

Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT
Condition:   Migraine DisordersIntervention:   Drug: ProchlorperazineSponsor:   Los Angeles Biomedical Research InstituteRecruiting - verified May 2016 (Source:
Source: - May 17, 2016 Category: Research Source Type: clinical trials

The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine
Condition:   HeadacheInterventions:   Drug: Prochlorperazine;   Drug: Ketamine;   Drug: Diphenhydromine;   Drug: Ondansetron;   Drug: Normal SalineSponsor:   University Medical Center of Southern NevadaNot yet recruiting - verified January 2016 (Source:
Source: - January 13, 2016 Category: Research Source Type: clinical trials