Causal associations between Helicobacter pylori infection and pregnancy and neonatal outcomes: a two-sample Mendelian randomization study
ConclusionOur two-sample MR study demonstrated a causal relationship of H. pylori infection with preeclampsia-eclampsia and premature rupture of membranes. The findings confirm the epidemiological evidence on the adverse impact of H. pylori in pregnancy. Further studies are needed to elucidate the pathophysiological mechanisms and assess the effectiveness of pre-pregnancy screening and preventive eradication. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 14, 2024 Category: Microbiology Source Type: research
Modelling pre-eclampsia and its cardiovascular effects
Nature Reviews Cardiology, Published online: 13 March 2024; doi:10.1038/s41569-024-01006-0In this Tools of the Trade article, Olivera describes a rat model of pre-elampsia that has been instrumental for investigating potential long-term cardiovascular effects in offspring. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - March 13, 2024 Category: Cardiology Authors: Sol Olivera Delyth Graham Source Type: research
Causal relationship between iron status and preeclampsia-eclampsia: a Mendelian randomization analysis
CONCLUSIONS: Our study did not detect a genetic causal relationship between iron status and preeclampsia/eclampsia. Nonetheless, this does not rule out a relationship between the two at other mechanistic levels.PMID:38471132 | DOI:10.1080/10641963.2024.2321148 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - March 12, 2024 Category: Cardiology Authors: Xiaofeng Yang Jiachun Wei Lu Sun Qimei Zhong Xiaoxuan Zhai Ya Chen Shujuan Luo Chunyan Tang Lan Wang Source Type: research
Causal relationship between iron status and preeclampsia-eclampsia: a Mendelian randomization analysis
CONCLUSIONS: Our study did not detect a genetic causal relationship between iron status and preeclampsia/eclampsia. Nonetheless, this does not rule out a relationship between the two at other mechanistic levels.PMID:38471132 | DOI:10.1080/10641963.2024.2321148 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - March 12, 2024 Category: Cardiology Authors: Xiaofeng Yang Jiachun Wei Lu Sun Qimei Zhong Xiaoxuan Zhai Ya Chen Shujuan Luo Chunyan Tang Lan Wang Source Type: research
Causal relationship between iron status and preeclampsia-eclampsia: a Mendelian randomization analysis
CONCLUSIONS: Our study did not detect a genetic causal relationship between iron status and preeclampsia/eclampsia. Nonetheless, this does not rule out a relationship between the two at other mechanistic levels.PMID:38471132 | DOI:10.1080/10641963.2024.2321148 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - March 12, 2024 Category: Cardiology Authors: Xiaofeng Yang Jiachun Wei Lu Sun Qimei Zhong Xiaoxuan Zhai Ya Chen Shujuan Luo Chunyan Tang Lan Wang Source Type: research
Temporal Trend in Maternal Morbidity and Comorbidity
Conclusion The rise in the prevalence of comorbidity in pregnancy seems to fuel the rise in SMM. Interventions to prevent SMM should include the management and prevention of pregnancy-associated hypertension.
Key Points
[...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - March 12, 2024 Category: Perinatology & Neonatology Authors: Diab, Yara H. Huang, Jim Nehme, Lea Saade, George Kawakita, Tetsuya Tags: Original Article Source Type: research
Impact of physical activity on preeclampsia and angiogenic markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort
CONCLUSIONS: In the FINNPEC study cohort, there was no association between physical activity and PE and no associations of physical activity in pregnant women with and without PE with maternal serum concentrations of sFlt-1, PlGF and sEng and sFlt-1/PlGF ratio.PMID:38466911 | DOI:10.1080/07853890.2024.2325480 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Noora Jaatinen Eeva Ekholm Finnpec Hannele Laivuori Tiina J ääskeläinen Source Type: research
Impact of physical activity on preeclampsia and angiogenic markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort
CONCLUSIONS: In the FINNPEC study cohort, there was no association between physical activity and PE and no associations of physical activity in pregnant women with and without PE with maternal serum concentrations of sFlt-1, PlGF and sEng and sFlt-1/PlGF ratio.PMID:38466911 | PMC:PMC10930136 | DOI:10.1080/07853890.2024.2325480 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Noora Jaatinen Eeva Ekholm Finnpec Hannele Laivuori Tiina J ääskeläinen Source Type: research
High level 27-HC impairs trophoblast cell invasion and migration via LXR in pre-eclampsia
CONCLUSION: 27-HC inhibits the invasion and migration ability of trophoblast cells by activating the LXR signaling pathway, which is involved in the pathogenesis of PE.PMID:38462209 | DOI:10.1016/j.yexcr.2024.113979 (Source: Experimental Cell Research)
Source: Experimental Cell Research - March 10, 2024 Category: Cytology Authors: Hai Tong Tingting Wang Ruixin Chen Pingsong Jin Youqing Jiang Xue Zhang Hongbo Qi Source Type: research
High level 27-HC impairs trophoblast cell invasion and migration via LXR in pre-eclampsia
CONCLUSION: 27-HC inhibits the invasion and migration ability of trophoblast cells by activating the LXR signaling pathway, which is involved in the pathogenesis of PE.PMID:38462209 | DOI:10.1016/j.yexcr.2024.113979 (Source: Experimental Cell Research)
Source: Experimental Cell Research - March 10, 2024 Category: Cytology Authors: Hai Tong Tingting Wang Ruixin Chen Pingsong Jin Youqing Jiang Xue Zhang Hongbo Qi Source Type: research
High level 27-HC impairs trophoblast cell invasion and migration via LXR in pre-eclampsia
CONCLUSION: 27-HC inhibits the invasion and migration ability of trophoblast cells by activating the LXR signaling pathway, which is involved in the pathogenesis of Pre-eclampsia(PE).PMID:38462209 | DOI:10.1016/j.yexcr.2024.113979 (Source: Experimental Cell Research)
Source: Experimental Cell Research - March 10, 2024 Category: Cytology Authors: Hai Tong Tingting Wang Ruixin Chen Pingsong Jin Youqing Jiang Xue Zhang Hongbo Qi Source Type: research
Does calcium prevent pre-eclampsia?
BJOG. 2024 Mar 8. doi: 10.1111/1471-0528.17805. Online ahead of print.NO ABSTRACTPMID:38456342 | DOI:10.1111/1471-0528.17805 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - March 8, 2024 Category: OBGYN Authors: Steve Thornton Source Type: research
Does calcium prevent pre-eclampsia?
BJOG. 2024 Mar 8. doi: 10.1111/1471-0528.17805. Online ahead of print.NO ABSTRACTPMID:38456342 | DOI:10.1111/1471-0528.17805 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - March 8, 2024 Category: OBGYN Authors: Steve Thornton Source Type: research
Does calcium prevent pre-eclampsia?
BJOG. 2024 Mar 8. doi: 10.1111/1471-0528.17805. Online ahead of print.NO ABSTRACTPMID:38456342 | DOI:10.1111/1471-0528.17805 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - March 8, 2024 Category: OBGYN Authors: Steve Thornton Source Type: research
Multicentre randomised trial of screening with sFlt1/PlGF and planned delivery to prevent pre-eclampsia at term: protocol of the PE37 study
This study was accepted by the Clinical Research Ethics Committee of Hospital Clinic Barcelona on 20 November 2020. Subsequent approval by individual ethical committees and competent authorities was granted. The study results will be published in peer-reviewed journals and disseminated at international conferences.
Trial registration number
NCT04766866. (Source: BMJ Open)
Source: BMJ Open - March 8, 2024 Category: General Medicine Authors: Llurba, E., Crispi, F., Crovetto, F., Youssef, L., Delgado, J. L., Puig, I., Mora, J., Krofta, L., Mackova, K., Martinez-Varea, A., Tubau, A., Ruiz, A., Paya, A., Prat, M., Chantraine, F., Comas, C., Kajdy, A., Lopez-Tinajero, M. F., Figueras, F., Grataco Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
