Management of new-onset hypertension in pregnancy
Hypertensive disorders affect approximately 8 –10% of all pregnancies and include pre-eclampsia, gestational hypertension and pre-existing chronic hypertension, which may be primary or secondary. New onset hypertension in pregnancy is defined as a sustained systolic blood pressure (sBP) ≥140 mmHg and/or diastolic blood pressure (dBP) ≥90  mmHg, and severe hypertension diagnosed when sBP ≥160 mmHg and/or dBP ≥110 mmHg. Gestational hypertension and pre-eclampsia are most common, affecting 4.2–7.9% and 1.5–7.7% respectively. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - February 17, 2024 Category: OBGYN Authors: Bernadette Jenner, Ian B. Wilkinson Tags: Case-based learning Source Type: research

Early treatment will prevent feto-maternal complications in thyroid disorders during pregnancy: A prospective study
CONCLUSIONS: Due to the high prevalence of thyroid disorders during pregnancy, universal screening of thyroid disorders should be done in early pregnancy instead of high-risk screening. Early detection and early treatment in the first 10 weeks of pregnancy help to prevent maternal and fetal complications of thyroid disorders in pregnancy. Pre-eclampsia is to be monitored in treated pregnant females with hypothyroidism.PMID:38361867 | PMC:PMC10866218 | DOI:10.4103/jfmpc.jfmpc_1185_23 (Source: Primary Care)
Source: Primary Care - February 16, 2024 Category: Primary Care Authors: Smruti Vaishnav Dharak Pandya Rama Shrivastava Nimeshkumar Patel Ajay G Phatak Alpaben Patel Source Type: research

Early treatment will prevent feto-maternal complications in thyroid disorders during pregnancy: A prospective study
CONCLUSIONS: Due to the high prevalence of thyroid disorders during pregnancy, universal screening of thyroid disorders should be done in early pregnancy instead of high-risk screening. Early detection and early treatment in the first 10 weeks of pregnancy help to prevent maternal and fetal complications of thyroid disorders in pregnancy. Pre-eclampsia is to be monitored in treated pregnant females with hypothyroidism.PMID:38361867 | PMC:PMC10866218 | DOI:10.4103/jfmpc.jfmpc_1185_23 (Source: Primary Care)
Source: Primary Care - February 16, 2024 Category: Primary Care Authors: Smruti Vaishnav Dharak Pandya Rama Shrivastava Nimeshkumar Patel Ajay G Phatak Alpaben Patel Source Type: research

Maternal Mortality due to Pregnancy-Related Acute Kidney Injury (PRAKI); A Study of the Epidemiological Factors and Possible Solutions
ConclusionThis study highlights the urgent need for preventive and therapeutic interventions to reduce maternal mortality related to PRAKI. On the basis of the key findings, PRAKI prevention bundles were proposed. The PRAKI prevention (patient) bundle included regular BP measurement during ANC visits, healthcare check-up if there is fever or drop in urine during pregnancy or immediate postpartum. The PRAKI prevention (obstetrician) bundle included regular BP measurement, urine culture, avoidance of nephrotoxic agents and hourly urine output monitoring during delivery and immediate postpartum. Implementing preventive measur...
Source: The Journal of Obstetrics and Gynecology of India - February 16, 2024 Category: OBGYN Source Type: research

Labor induction at 41+0 gestational weeks or expectant management for the nulliparous woman: The Finnish randomized controlled multicenter trial
ConclusionsOffering labor induction to nulliparous women at 41+0 gestational weeks may decrease the probability of operative delivery, postpartum hemorrhage, and neonatal weight ≥4000 g. However, this study was underpowered to affirm the trends of rising rates of CS and adverse neonatal outcomes in the expectant management group. Thus, expectant management could remain an option for some, as one in two women with expectant management had a spontaneous onset of labor. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 15, 2024 Category: OBGYN Authors: Katariina Place, Leena Rahkonen, Aydin Tekay, Kirsi V äyrynen, Maija‐Riitta Orden, Marja Vääräsmäki, Jukka Uotila, Kati Tihtonen, Kirsi Rinne, Kaarin Mäkikallio, Seppo Heinonen, Heidi Kruit Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal metabolic profiling across body mass index groups: An exploratory longitudinal study
ConclusionsOverweight or obese women had smaller pregnancy-related metabolic alterations than normal-weight/underweight women. There was a trend toward higher triglyceride and VLDL particle concentration in overweight/obese women. As this was a hypothesis-generating study, the similarities with late-onset pre-eclampsia warrant further investigation. The unfavorable development of fatty acid composition in overweight/obese women, with possible implication for the offspring, should also be studied further in the future. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 15, 2024 Category: OBGYN Authors: Hege Nyhus Skytte, Marie Cecilie Paasche Roland, Jacob Juel Christensen, Kirsten Bj ørklund Holven, Tove Lekva, Nina Gunnes, Trond Melbye Michelsen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Subsequent pregnancy outcomes after second trimester miscarriage or termination for medical/fetal reason: A systematic review and meta ‐analysis of observational studies
ConclusionsVery low certainty evidence suggests there may be an increased risk of preterm birth in a subsequent pregnancy after a late miscarriage. However, evidence is limited. Larger, higher quality cohort studies are needed to investigate this potential association. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 15, 2024 Category: OBGYN Authors: Keya Patel, Danielle Pirie, Alexander E. P. Heazell, Bethan Morgan, Andrea Woolner Tags: SYSTEMATIC REVIEW Source Type: research

Use of the USCOM ® noninvasive cardiac output measurement system to predict the development of pre-eclampsia in hypertensive pregnancies
CONCLUSIONS: Our group was unable to successfully predict the onset of PE or severe PE based on hemodynamic parameters measured with the USCOM. It is possible this relates to the high proportion of women on antihypertensive medication at recruitment.PMID:38353244 | DOI:10.1080/10641955.2024.2310607 (Source: Hypertension in Pregnancy)
Source: Hypertension in Pregnancy - February 14, 2024 Category: OBGYN Authors: Jack George Mangos Shyamalee Crocker Macayla Flood Jade Martyn Lynne Roberts Amanda Henry Franziska Pettit Source Type: research