Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Impact of fetal growth restriction on pregnancy outcome in women undergoing expectant management for preterm pre-eclampsia
CONCLUSION: FGR is commonly present in women with early preterm preeclampsia being managed expectantly and outcomes are poorer. FGR is associated with a shorter latency, more emergency caesarean deliveries, fewer successful inductions, and increased rates of neonatal morbidity and death. This article is protected by copyright. All rights reserved.PMID:37289938 | DOI:10.1002/uog.26282 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - June 8, 2023 Category: Radiology Authors: C A Cluver L Bergman J Bergkvist H Imberg L Geerts D R Hall B W Mol S Tong S P Walker Source Type: research
Corrigendum: Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions
(Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 1, 2023 Category: Drugs & Pharmacology Source Type: research
Protective effects of esomeprazole against cisplatin-induced ototoxicity: an in vitro and in vivo study
In this study, we aimed to identify novel compounds that could afford protection against cisplatin-induced ototoxicity by employing both cell- and zebrafish (Danio rerio)-based screening platforms. We screened 923 US Food and Drug Administration-approved drugs to identify potential compounds exhibiting protective effects against cisplatin-induced ototoxicity in HEI-OC1 cells (auditory hair cell line). The screening strategy identified esomeprazole and dexlansoprazole as the primary hit compounds. Subsequently, we examined the effects of these compounds on cell viability and apoptosis. Our results revealed that esomeprazole...
Source: Aquatic Toxicology - May 21, 2023 Category: Toxicology Authors: Hanul Jeon In Sik Song Jin-Gyeong Park Hyejin Lee Eunjung Han Saemi Park Yunkyoung Lee Chi-Man Song Wooyoung Hur In-Gyun Lee June Choi Source Type: research
Protective effects of esomeprazole against cisplatin-induced ototoxicity: an in vitro and in vivo study
In this study, we aimed to identify novel compounds that could afford protection against cisplatin-induced ototoxicity by employing both cell- and zebrafish (Danio rerio)-based screening platforms. We screened 923 US Food and Drug Administration-approved drugs to identify potential compounds exhibiting protective effects against cisplatin-induced ototoxicity in HEI-OC1 cells (auditory hair cell line). The screening strategy identified esomeprazole and dexlansoprazole as the primary hit compounds. Subsequently, we examined the effects of these compounds on cell viability and apoptosis. Our results revealed that esomeprazole...
Source: Aquatic Toxicology - May 21, 2023 Category: Toxicology Authors: Hanul Jeon In Sik Song Jin-Gyeong Park Hyejin Lee Eunjung Han Saemi Park Yunkyoung Lee Chi-Man Song Wooyoung Hur In-Gyun Lee June Choi Source Type: research
Protective effects of esomeprazole against cisplatin-induced ototoxicity: an in vitro and in vivo study
In this study, we aimed to identify novel compounds that could afford protection against cisplatin-induced ototoxicity by employing both cell- and zebrafish (Danio rerio)-based screening platforms. We screened 923 US Food and Drug Administration-approved drugs to identify potential compounds exhibiting protective effects against cisplatin-induced ototoxicity in HEI-OC1 cells (auditory hair cell line). The screening strategy identified esomeprazole and dexlansoprazole as the primary hit compounds. Subsequently, we examined the effects of these compounds on cell viability and apoptosis. Our results revealed that esomeprazole...
Source: Aquatic Toxicology - May 21, 2023 Category: Toxicology Authors: Hanul Jeon In Sik Song Jin-Gyeong Park Hyejin Lee Eunjung Han Saemi Park Yunkyoung Lee Chi-Man Song Wooyoung Hur In-Gyun Lee June Choi Source Type: research
