Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany
ConclusionOur large study supports existing evidence that PPI use is related to an increased risk of dementia. (Source: Drugs and Aging)
Source: Drugs and Aging - May 13, 2023 Category: Geriatrics Source Type: research
The Role of Endoplasmic Reticulum Stress in Gastroesophageal Reflux Disease Symptoms and Treatment
CONCLUSION: Endoplasmic reticulum stress can be for evaluating the clinical improvement and the effectiveness of treatment in gastroesophageal reflux disease.PMID:37158535 | DOI:10.5152/tjg.2023.21282 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - May 9, 2023 Category: Gastroenterology Authors: Elmas Kasap Tahir Buran Aysun Toraman Avcu P ınar Solmaz Hasdemir Erdal Balcan Çağdaş Aktan Mehmet Korkmaz Source Type: research
The efficacy and mechanism of vonoprazan-containing triple therapy in the eradication of Helicobacter pylori
Conclusion: In the Chinese population, 14-day VPZ-containing triple therapy was safe and more effective and can be used clinically as first-line H. pylori treatment.Clinical Trial Registration:ClinicalTrials.gov, identifier NCT05097846 (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - May 5, 2023 Category: Drugs & Pharmacology Source Type: research
[ASAP] Continuous Flow Synthesis of Esomeprazole via Asymmetric Sulfoxidation
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00012 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2023 Category: Chemistry Authors: Tianxiang Gao, Jingnan Zhao, Huinan Sun, Jianing Li, Cunfei Ma, and Qingwei Meng Source Type: research
Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions
Conclusion: According to relevant regulatory standards, esomeprazole enteric-coated generic and reference products exhibited bioequivalence and good safety in healthy Chinese subjects.Clinical Trials Registration:http://www.chinadrugtrials.org.cn/index.html, identifier CTR20171347 and CTR20171484 (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - April 28, 2023 Category: Drugs & Pharmacology Source Type: research
Combination of vonoprazan and amoxicillin as the first-line Helicobacter pylori eradication therapy: a multicenter, prospective, randomized, parallel-controlled study
This study aimed to analyze the efficacy and safety of a 14-day combination of vonoprazan and amoxicillin as the first-line eradication therapy forH. pylori infection and compared them with those of the bismuth quadruple therapy. A prospective randomized clinical trial (RCT) was designed, involving patients withH. pylori infection in 6 institutions who did not receive any treatment yet. They were randomly assigned into the VA-dual group (vonoprazan 20 mg b.i.d + amoxicillin 750 mg q.i.d) or EACP-quadruple group (esomeprazole 20 mg + amoxicillin 1000 mg + clarithromycin 500 mg + colloidal bismuth subci...
Source: Clinical and Experimental Medicine - April 28, 2023 Category: Research Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
