Gastroprotective Effect of 2,3-Dimethylquinoxaline Against Indomethacin-Induced Gastric Ulcer in Rat
CONCLUSION: DMQ demonstrated promising gastroprotective effects against IND-induced gastric ulcers, as evidenced by alterations in histopathological data and upregulation of gene expression.PMID:38566982 | PMC:PMC10986627 | DOI:10.2147/JIR.S453425 (Source: Cancer Control)
Source: Cancer Control - April 3, 2024 Category: Cancer & Oncology Authors: Abdelbagi Alfadil Source Type: research

Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor: A Pilot Study on Comparable Efficacy in the Treatment of Gastroesophageal Reflux-Related Cough
In conclusion, vonoprazan may be comparable to esomeprazole in cough symptom relief in GERC during the 2-month treatment period, but possibly provides better gains on classic reflux symptoms and quality-of-life. The long-term efficacy of P-CABs on GERC may be worth further exploration. Trial Registration: Chinese Clinical Trial Registry Identifier: ChiCTR2200067089.PMID:38528386 | DOI:10.4168/aair.2024.16.2.191 (Source: Allergy, Asthma and Immunology Research)
Source: Allergy, Asthma and Immunology Research - March 26, 2024 Category: Allergy & Immunology Authors: Shuxin Zhong Mingyu Zhong Liman Fang Haopeng Zhi Xiaolong Ji Kailun Tang Chen Zhan Xu Shi Mo Xian Wanjun Wang Jing Li Wei Luo Kefang Lai Ruchong Chen Source Type: research

Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor: A Pilot Study on Comparable Efficacy in the Treatment of Gastroesophageal Reflux-Related Cough
In conclusion, vonoprazan may be comparable to esomeprazole in cough symptom relief in GERC during the 2-month treatment period, but possibly provides better gains on classic reflux symptoms and quality-of-life. The long-term efficacy of P-CABs on GERC may be worth further exploration. Trial Registration: Chinese Clinical Trial Registry Identifier: ChiCTR2200067089.PMID:38528386 | PMC:PMC10973636 | DOI:10.4168/aair.2024.16.2.191 (Source: Allergy, Asthma and Immunology Research)
Source: Allergy, Asthma and Immunology Research - March 26, 2024 Category: Allergy & Immunology Authors: Shuxin Zhong Mingyu Zhong Liman Fang Haopeng Zhi Xiaolong Ji Kailun Tang Chen Zhan Xu Shi Mo Xian Wanjun Wang Jing Li Wei Luo Kefang Lai Ruchong Chen Source Type: research