Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research

Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
World J Cardiol. 2023 Aug 26;15(8):375-394. doi: 10.4330/wjc.v15.i8.375.ABSTRACTAspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) treatment is often prescribed in these patients, as gastrointestinal complications are relatively frequent. On the other hand, a potential increased risk of cardiovascular events has been suggested in patients treated with PPIs; in particular, it has been discussed whether these drugs may reduce the cardiovascular protection of clopidogrel, due to pharmacodynamic an...
Source: World Journal of Cardiology - September 29, 2023 Category: Cardiology Authors: Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicol ò Renda Vincenzo Abrignani Source Type: research