Evaluation of the Efficacy and Safety of DW1903 in Patients with Gastritis: A Randomized, Double-Blind, Noninferiority, Multicenter, Phase 3 study
CONCLUSIONS: DW1903 of a low-dose PPI was not inferior to DW1903R1 of H2RA. Thus, lowdose PPI can be a novel option for treating gastritis (ClinicalTrials.gov Identifier: NCT05163756).PMID:37309193 | DOI:10.5009/gnl220446 (Source: Gut and Liver)
Source: Gut and Liver - June 13, 2023 Category: Gastroenterology Authors: Jie-Hyun Kim Hwoon-Yong Jung In Kyung Yoo Seon-Young Park Jae Gyu Kim Jae Kyu Sung Jin Seok Jang Gab Jin Cheon Kyoung Oh Kim Tae Oh Kim Soo Teik Lee Kwang Bum Cho Hoon Jai Chun Jong-Jae Park Moo In Park Jae-Young Jang Seong Woo Jeon Jin Woong Cho Dae Hwan Source Type: research

Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research

Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research

Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research

Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research

Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research