Blue Laser Imaging, Blue Light Imaging, and Linked Color Imaging for the Detection and Characterization of Colorectal Tumors.
Authors: Yoshida N, Dohi O, Inoue K, Yasuda R, Murakami T, Hirose R, Inoue K, Naito Y, Inada Y, Ogiso K, Morinaga Y, Kishimoto M, Rani RA, Itoh Y Abstract A laser endoscopy system was developed in 2012. The system allows blue laser imaging (BLI), BLI-bright, and linked color imaging (LCI) to be performed as modes of narrow-band light observation; these modes have been reported to be useful for tumor detection and characterization. Furthermore, an innovative endoscopy system using four-light emitting diode (LED) multilight technology was released in 2016 to 2017 in some areas in which laser endoscopes have not been ...
Source: Gut and Liver - December 7, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Weight Management as a Treatment Option for Gastroesophageal Reflux Disease: A Mechanical or Metabolic Rescuer?
Authors: Lee H PMID: 30466199 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - November 24, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Efficacy of Direct-Acting Antivirals in Patients with Hepatitis C Virus/Human Immunodeficiency Virus Coinfection: A Gap between Clinical Trial and Real Practice.
Authors: Kim DY PMID: 30466200 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - November 24, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

The Choice of Interventional Treatment of Gastric Variceal Hemorrhage: What Is Better?
Authors: Kim MY PMID: 30466201 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - November 24, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

The More, the Better? Predicting Prognosis in Primary Biliary Cholangitis.
Authors: Kim BH PMID: 30466202 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - November 24, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

von Willebrand Factor Antigen Predicts Outcomes in Patients after Liver Resection of Hepatocellular Carcinoma.
Conclusions: vWF-Ag may serve as a prognostic marker for the outcome of patients undergoing liver resection for HCC that is closely connected to tumor size, postoperative complication rate and long-term outcome. PMID: 30428508 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 16, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Current Definition of and Controversial Issues Regarding Postoperative Pancreatic Fistulas.
Authors: Marchegiani G, Andrianello S, Salvia R, Bassi C Abstract The International Study Group for Pancreatic Fistula (ISGPF) made the first attempt to standardize the outcome measure of fistulas in the field of pancreatic surgery by publishing the definition and classification of postoperative pancreatic fistulas (POPFs) in 2005. POPFs were determined by any measurable volume of fluid output via an operatively placed drain with amylase activity greater than three times the upper normal serum value. Taking into account more than 10 years of reported experience worldwide, the updated definition published in 2016 by...
Source: Gut and Liver - November 14, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Insulin Resistance Is Associated with Early Gastric Cancer: A Prospective Multi-Center Case Control Study.
Conclusions: Hyperglycemia, a lower high-density lipoprotein cholesterol level, and a low HOMA-IR level appear to be associated with early gastric cancer risk. PMID: 30400721 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Statin Exposure Is Not Associated with Reduced Prevalence of Colorectal Neoplasia in patients with Inflammatory Bowel Disease.
This study examined the association of statin exposure with dysplasia and CRC in patients with IBD undergoing dysplasia surveillance colonoscopies. Methods: A cohort of patients with IBD undergoing colonoscopic surveillance for dysplasia and CRC at a single academic medical center were studied. The inclusion criteria were IBD involving the colon for>8 years (or any colitis duration if associated with primary sclerosing cholangitis [PSC]) and at least two colonoscopic surveillance exams. The exclusion criteria were CRC or high-grade dysplasia (HGD) prior to or at enrollment, prior colectomy, or limited (
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Treatment Outcome and Renal Safety of 3-Year Tenofovir Disoproxil Fumarate Therapy in Chronic Hepatitis B Patients with Preserved Glomerular Filtration Rate.
Conclusions: TDF therapy appears to be an effective treatment option for CHB patients with a preserved GFR. However, patients with underlying DM and initial mild renal dysfunction (eGFR, 60 to 89 mL/min/1.73 m2) have an increased risk of renal impairment. PMID: 30400723 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Predicting Malignancy Risk in Gastrointestinal Subepithelial Tumors with Contrast-Enhanced Harmonic Endoscopic Ultrasonography Using Perfusion Analysis Software.
Conclusions: CEH-EUS with perfusion analysis using perfusion analysis software could be a quantitative and independent method for predicting malignancy risk in gastrointestinal SETs. PMID: 30400724 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Safety and Efficacy of Low-Volume Preparation in the Elderly: Oral Sulfate Solution on the Day Before and Split-Dose Regimens (SEE SAFE) Study.
Conclusions: In elderly individuals, OSS with a split-dose regimen has greater acceptability and comparable efficacy in bowel cleansing compared to 4L PEG. (Clinical trials registration number: NCT03112967). PMID: 30400725 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Continuous Infusion Versus Intermittent Dosing with Pantoprazole for Gastric Endoscopic Submucosal Dissection.
Conclusions: Intermittent dosing with pantoprazole is sufficient and cost-effective for the prevention of gastric ESD-related bleeding. Operators should consider tumor characteristics when planning ESD to minimize the risk of intraprocedural bleeding, and patients with large iatrogenic ulcers should be carefully monitored for postprocedural bleeding. PMID: 30400726 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Assessment of Clinical Outcomes after Peroral Endoscopic Myotomy via Esophageal Distensibility Measurements with the Endoluminal Functional Lumen Imaging Probe.
This study aimed to assess the utility of EndoFLIP in patients who had achalasia treated with peroral endoscopic myotomy (POEM). We hypothesized that improvement in the distensibility index (DI) is correlated with the postoperative clinical outcome of POEM. Methods: Patients who underwent POEM for achalasia at Cha Bundang Medical Center were included. Physiological measurements of the lower esophageal sphincter (LES) pressure before and after POEM were assessed using EndoFLIP. Patients' symptoms were recorded using the Eckardt score. Results: A total of 52 patients with achalasia were included in this study. Patien...
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Usefulness of Personal Bowel Habits as a Predictive Factor for Inadequate Bowel Preparation for Colonoscopy: A Prospective Questionnaire-Based Observational Study.
Conclusion: Straining is a significant predictor for inadequate bowel preparation. For patients with straining during bowel movements, an intensified preparation regimen should be considered. PMID: 30400728 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Efficacy and Safety of Daclatasvir and Asunaprevir in Patients with Hepatitis C Virus Genotype 1b Infection on Hemodialysis.
Conclusions: DCV and ASV combination therapy in chronic hemodialysis patients with HCV infection achieved a high SVR12 rate with few AEs. To maximize the SVR12 rate, it is important to identify candidates by baseline RAV testing. Close monitoring of the safety and tolerability of DCV and ASV may be necessary in HCV-infected patients on hemodialysis. (ClinicalTrials.gov ID NCT02580474). PMID: 30400729 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Distinction between Chronic Enteropathy Associated with the SLCO2A1 Gene and Crohn's Disease.
Conclusions: Immunohistochemical staining for SLCO2A1 in gastroduodenal tissues obtained by endoscopic biopsy is considered useful for the distinction of CEAS from CD. PMID: 30400730 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Efficacy of Nab-Paclitaxel Plus Gemcitabine and Prognostic Value of Peripheral Neuropathy in Patients with Metastatic Pancreatic Cancer.
Conclusions: Nab-P/Gem is a reasonable choice for treating MPC, as it shows a considerable disease control rate while the treatment-related peripheral neuropathy was tolerable. The prognostic role of treatment-related neuropathy was limited. PMID: 30400731 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Prognostic Value of Biochemical Response Models for Primary Biliary Cholangitis and the Additional Role of the Neutrophil-to-Lymphocyte Ratio.
Conclusions: The UK-PBC and GLOBE scores showed good prognostic performance in Korean patients with PBC. In addition, a high NLR was associated with a poorer prognosis. Including the NLR in prognostic models may further help to stratify patients with PBC. PMID: 30400732 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Effects of 17 β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model.
Conclusions: E2 acts through the estrogen receptor β signaling pathway to elicit anti-inflammatory effects on intestinal barrier by inducing the expression of MUC2 and tight junction molecules and inhibiting pro-inflammatory cytokines. PMID: 30400733 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Recurrent Clostridium difficile Infection: Risk Factors, Treatment, and Prevention.
Authors: Song JH, Kim YS Abstract The most common cause of antibiotic-associated diarrhea is Clostridium difficile infection (CDI). Recurrent C. difficile infection (rCDI) often occurs after successful treatment of CDI. Due to the increased incidence and the difficulty in treating rCDI, it is becoming an important clinical issue. Identifying risk factors is helpful for early detection, treatment, and prevention of rCDI. Advanced age, use of antibiotics, gastric acid suppression, and infection with a hypervirulent strain are currently regarded as the major risk factors for rCDI. Several treatment modalities, includi...
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Relationship between Telomere Maintenance and Liver Disease.
Authors: Barnard A, Moch A, Saab S Abstract Previous studies have established a correlation between increasing chronological age and risk of cirrhosis. This pattern raised interest in the role of telomeres and the telomerase complex in the pathogenesis of liver fibrosis and cirrhosis. This review aims to summarize and analyze the current understanding of telomere regulation in hepatocytes and lymphocytes and how this ultimately relates to the development of liver fibrosis. Notably, in chronic viral hepatitis, telomere shortening in hepatocytes and lymphocytes occurs in such a way that may promote further viral repl...
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Effects of Moderate Alcohol Drinking in Patients with Nonalcoholic Fatty Liver Disease.
Authors: Kwon I, Jun DW, Moon JH Abstract Whether moderate alcohol intake is beneficial remains an unsolved issue. Recent studies have suggested that moderate alcohol consumption is associated with beneficial effects related to the prevention of cardiovascular diseases. Moderate alcohol consumption leads to a higher risk of hepatocellular carcinoma in patients with chronic viral liver diseases. However, the effects of moderate alcohol intake in patients with nonalcoholic fatty liver disease are unclear. In this review, we analyzed, from various perspectives, the effect of moderate alcohol consumption in patients wi...
Source: Gut and Liver - November 9, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

What Are the Clinical Features and Etiology of Eosinophilic Liver Infiltration?
Conclusions: This large ELI study is unique in that the incidence rate, underlying diseases, and clinical courses were comprehensively evaluated. Clinicians should investigate the etiology of ELI, as several of the underlying diseases require intervention rather than observation. PMID: 30376702 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - November 1, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Are the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Prognostic Factors for Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiotherapy?
Authors: Yu JJ, Sun LY, Quan B, Yang T PMID: 30304762 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - October 12, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis.
Authors: Tanaka A Abstract Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories: primary sclerosing cholangitis (PSC), secondary cholangitis, and IgG4-related sclerosing cholangitis (IgG4-SC). SC categories share similar clinical features, such as cholestasis. Patients with SC present with cholestatic symptoms, including jaundice and pruritus, and blood tests reveal elevation of cholestatic enzymes. Cholangiography, endoscopic or magnetic, is inevitably required for making a ...
Source: Gut and Liver - September 14, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Syndecan-2 Methylation as a New Biomarker for Early Detection of Colorectal Neoplasm.
Authors: Kim JH, Park SC PMID: 30205668 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - September 14, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Factors Predictive of Malignancy Potency in Pure Branch Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas without Mural Nodules.
Authors: Lee TH PMID: 30205669 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - September 14, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

A Program to Treat Hepatitis B in North Korea: A Model of Antiviral Therapy in a Resource-Poor Setting.
Authors: Lee AU, Linton H, Kilsby M, Hilmers DC Abstract Despite the well-proven, safe and effective therapies for hepatitis B infection, delivery of treatment remains a significant challenge in resource-poor settings. Geopolitical and economic restrictions present additional difficulties in providing care in North Korea. However, treatment of patients with chronic hepatitis B remains a top priority for both the North Korean Ministry of Public Health and international agencies working in North Korean hepatitis healthcare facilities. Working in partnership, a path was created to institute this much-needed program. A...
Source: Gut and Liver - August 31, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Age-Related Decrease in Skeletal Muscle Mass Is An Independent Risk Factor for Incident NAFLD: A 10-Year Retrospective Cohort Study.
Conclusions: A progressive increase in fat mass and a loss of ASM with aging were significantly associated with incident NAFLD. This association was more prominent in nonobese subjects. PMID: 30037166 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

An Economic Modeling Study of Helicobacter pylori Eradication: Comparison of DPO-Based PCR and Empirical Treatment.
Authors: Gweon TG, Kim JS, Kim BW Abstract Background/Aims: Dual priming oligonucleotide-based multiplex polymerase chain reaction (DPO-based PCR) can detect the presence of clarithromycin resistance without culture. The aim of this study was to investigate the cost-effectiveness of DPO-based PCR for Helicobacter pylori eradication. Methods: From 2015 to 2016, medical records of patients who received H. pylori eradication therapy were analyzed. Patients were divided into two groups: tailored group patients who were treated based on DPO-based PCR and empirical group patients. Eradication rate and medical cost, i...
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Peptide Nucleic Acid Probe-Based Analysis as a New Detection Method for Clarithromycin Resistance in Helicobacter pylori.
Conclusions: H. pylori clarithromycin resistance can be easily and accurately assessed by dual-labeled PNA probe-based melting curve analysis if probes are used based on the appropriate resistance-related mutations. This method is fast, simple, accurate, and adaptable for clinical samples. It may help clinicians choose a precise eradication regimen. PMID: 30037168 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Impact of Education on School Nurses' Knowledge of Inflammatory Bowel Disease.
Authors: Kim ES, Kwon KT, Kim SK, Kim M, Lee HS, Jang BI, Kim KO, Kim EY, Lee YJ, Hong SJ, Yang CH, Kang B, Choe BH Abstract Background/Aims: School nurses' knowledge of inflammatory bowel disease (IBD) has not been evaluated. We aimed to investigate school nurses' knowledge of IBD and determine whether education could improve this knowledge. Methods: School nurses were invited to complete self-reported questionnaires on IBD. Then, IBD specialists from tertiary referral hospitals provided a 60-minute lecture with educational brochures on two occasions, with a 3-month interval. Within 6 months after the educatio...
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Weight Loss as a Nonpharmacologic Strategy for Erosive Esophagitis: a 5-Year Follow-up Study.
Conclusions: EE resolution is associated with a decrease in BMI, and weight loss is potentially an effective GERD treatment. PMID: 30037170 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Association of Perianal Fistulas with Clinical Features and Prognosis of Crohn's Disease in Korea: Results from the CONNECT Study.
Authors: Chun J, Im JP, Kim JW, Lee KL, Choi CH, Kim H, Cheon JH, Ye BD, Kim YH, Kim YS, Jeen YT, Han DS, Kim WH, Kim JS Abstract Background/Aims: The disease course and factors associated with poor prognosis in Korean patients with Crohn's disease (CD) have not been fully determined. The aim of this study was to explore potential associations between the clinical characteristics and long-term outcomes of CD and perianal fistulas in a Korean population. Methods: The retrospective Crohn's Disease Clinical Network and Cohort (CONNECT) study enrolled patients diagnosed with CD between July 1982 and December 2008 f...
Source: Gut and Liver - July 26, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis.
Conclusions: Plasma M30 levels are often elevated in ALD and correlate with serum transaminases but do not reflect fibrosis. The usefulness as a prognostic marker awaits evaluation in prospective studies. PMID: 29976035 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - July 7, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Effects of Antiplatelet Agents on Bleeding after Endoscopic Resection of Gastric Tumor.
Authors: Ahn JY PMID: 29945420 [PubMed - indexed for MEDLINE] (Source: Gut and Liver)
Source: Gut and Liver - June 29, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Long-Term Clinical Efficacy and Safety of Endoscopic Submucosal Dissection for Early Gastric Cancer in Korea.
Authors: Kwon YH PMID: 29945421 [PubMed - indexed for MEDLINE] (Source: Gut and Liver)
Source: Gut and Liver - June 29, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Does Estrogen Contribute to the Esophageal Barrier Function in Women?
Authors: Iijima K PMID: 29945422 [PubMed - indexed for MEDLINE] (Source: Gut and Liver)
Source: Gut and Liver - June 29, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

An Elevated Platelet Count Increases the Risk of Relapse in Ulcerative Colitis Patients with Mucosal Healing.
Conclusions: The platelet count could be used as a predictor of relapse in UC patients with MH. PMID: 29945423 [PubMed - in process] (Source: Gut and Liver)
Source: Gut and Liver - June 29, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia: A Randomized, Controlled Trial.
Conclusions: Once-daily mosapride is not inferior to conventional mosapride in efficacy and is safe in patients with FD. PMID: 29938452 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Prospective Multicenter Study on the Challenges Inherent to Using Large Cell-Type Stents for Bilateral Stent-in-Stent Placement in Patients with Inoperable Malignant Hilar Biliary Obstruction.
Conclusions: Large cell-type stents for endoscopic bilateral stent-in-stent placement showed acceptable functional success and stent patency when technically successful. However, the technical difficulty associated with the entanglement of the second stent delivery sheath in the hook-cross-type vertex of the first stent may preclude large cell-type stents from being considered as a dedicated standard tool for stent-in-stent placement. PMID: 29938453 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Frequency and Characteristics of Interval Colorectal Cancer in Actual Clinical Practice: A KASID Multicenter Study.
Conclusions: The frequency of interval CRC among patients who had undergone a surveillance colonoscopy was 0.095%. While sharing some similar clinical features and survival outcomes, interval CRCs in Korea developed more often in males and on the left side in contrast to results from Western studies. PMID: 29938454 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Optimal Starting Age for Colorectal Cancer Screening in an Era of Increased Metabolic Unhealthiness: A Nationwide Korean Cross-Sectional Study.
Conclusions: Starting CRC screening earlier, namely, at 45 rather than at 50 years of age, may improve secondary prevention of CRC in Korea. PMID: 29938455 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Balloon-occluded Retrograde Transvenous Obliteration versus Transjugular Intrahepatic Portosystemic Shunt for the Management of Gastric Variceal Bleeding.
Conclusions: BRTO provides better bleeding control, rebleeding-free survival, and OS than TIPS for patients with GV bleeding. PMID: 29938456 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Development of a Novel Endoscopic Scoring System to Predict Relapse after Surgery in Intestinal Beh çet's Disease.
Conclusions: This new endoscopic scoring system could predict clinical relapse in patients after surgical resection of intestinal BD. PMID: 29938457 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Increased Expression of the Matrix-Modifying Enzyme Lysyl Oxidase-Like 2 in Aggressive Hepatocellular Carcinoma with Poor Prognosis.
Conclusions: LOXL2 expression represents a subgroup of HCCs with more aggressive behavior and is suggested to be a poor prognostic marker in HCC patients. PMID: 29938458 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Real-World Clinical Efficacy and Tolerability of Direct-Acting Antivirals in Hepatitis C Monoinfection Compared to Hepatitis C/HIV Coinfection in a Community Care Setting.
Conclusions: In a real-world setting, DAA regimens have lower SVR 12 in HCV/HIV coinfection than in HCV monoinfection. Further studies involving a higher number of HCV/HIV coinfected patients are needed to identify real predictors of a reduced response. PMID: 29938459 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Clinical Implication and Risk Factors for Malignancy of Atypical Gastric Gland during Forcep Biopsy.
Conclusions: Further evaluation and treatment should be considered for atypical gastric gland during forcep biopsy if there is a large-sized (>10 mm) lesion, depressed morphology, or surface nodularity. PMID: 29938460 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research

Regulatory Dendritic Cells Induced by Mesenchymal Stem Cells Ameliorate Dextran Sodium Sulfate-Induced Chronic Colitis in Mice.
Conclusions: Our data suggest that MSCs differentiate DCs into rDCs, which ameliorate chronic colitis. Thus, rDCs stimulated by MSCs may be therapeutically useful for the treatment of chronic inflammatory diseases. PMID: 29938461 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - June 28, 2018 Category: Gastroenterology Tags: Gut Liver Source Type: research