Family hope public appeal will help daughter beat cancer
A new treatment could give 18-month-old Alice Turner a chance to overcome neuroblastoma     (Source: The Irish Times - Health)
Source: The Irish Times - Health - March 10, 2014 Category: Consumer Health News Source Type: news

New targets for pediatric neuroblastoma therapies identified through improved screening
Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.Neuroblastomas, which account for 15 percent of childhood cancer deaths, happen when some cells do not differentiate and grow as they should. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2014 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Improved screening means new targets for pediatric neuroblastoma therapies
Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper recently published, a researcher unveils an improved screening technique that shows the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities. Neuroblastomas, which account for 15 percent of childhood cancer deaths, happen when some cells do not differentiate and grow as they should. A promising type of therapy called differentiation therapy targets these malignant cells so that they can resume the process of differentiating into mature cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 2, 2014 Category: Science Source Type: news

Improved screening means new targets for pediatric neuroblastoma therapies
(University of Texas Health Science Center at San Antonio) Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils an improved screening technique that shows the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2014 Category: Global & Universal Source Type: news

Reece Puddington, 11 year old battling cancer, reveals decision to stop treatment
Reece Puddington was first diagnosed with neuroblastoma in April 2008, with doctors telling him there was no cure. (Source: the Mail online | Health)
Source: the Mail online | Health - February 19, 2014 Category: Consumer Health News Source Type: news

Charity urges EU to give kids cancer drugs access
“Children with cancer ‘denied drugs because of EU rules’,” reports the BBC. This and other headlines in the media are based on a press release issued by the Institute of Cancer Research (ICR), London. The ICR has called for urgent changes in European Union (EU) regulations. It says pharmaceutical companies are often granted exemptions from carrying out trials of treatments in people under the age of 18. This in turn means that children can’t be offered the latest cancer drugs, the ICR says, because their safety and effectiveness hasn’t been tested. Under current EU rules, drugs...
Source: NHS News Feed - February 11, 2014 Category: Consumer Health News Tags: Cancer Medical practice QA articles Source Type: news

Children with cancer being denied life-saving drugs, scientists say
Call for change in EU regulations that allow pharmaceutical companies to opt out of children's trials for some cancer drugsPotentially life-saving drugs are being denied to children with cancer because they are not being put through the necessary clinical trials, say scientists who are calling for a change in European rules.The Institute of Cancer Research says the current EU regulations allow pharmaceutical companies to opt out of children's trials if a new drug is intended for an adult cancer that does not occur in children.But scientists say cancer drugs are increasingly aimed at molecular targets that may occur in many...
Source: Guardian Unlimited Science - February 10, 2014 Category: Science Authors: Sarah Boseley Tags: theguardian.com World news European Union Pharmaceuticals industry Health Medical research Society Cancer Business Science Source Type: news

'We buried her with her teddy, sticker book and comfort blanket': Parents' heartbreak as their daughter's 'winter virus' turns out to be rare and aggressive cancer
EXCLUSIVE: Lizzy Bremer, from south London, passed away from neuroblastoma two days after her second birthday. (Source: the Mail online | Health)
Source: the Mail online | Health - January 13, 2014 Category: Consumer Health News Source Type: news

Annabel Freyberg: 'I am lucky to be surrounded by kindness'
Shortly after her nine-year-old daughter died, Annabel Freyberg was herself diagnosed with terminal cancer. Here Annabel, a former interiors editor of the Telegraph Magazine, describes how her family, friends and a curious assortment of therapists kept her cheerful to the end     (Source: Telegraph Health)
Source: Telegraph Health - December 16, 2013 Category: Consumer Health News Tags: mesothelioma Blossom neuroblastoma cancer Annabel Freyberg Source Type: news

Footballers 'no more likely' to get Alzheimer's disease
Conclusion This study shows that in laboratory conditions, a Tau protein outside a neuron can be rapidly absorbed by the cell and can trigger Tau proteins inside the cell to form clumps instead of their usual function. The study then shows that the cell can release the Tau clumps and they can be absorbed by other neurones and cause Tau protein clumps to form. This gives a clue as to how neurofibrillary tangles might spread in the brain of people with Alzheimer’s disease.  However, there are limitations to this research, including: The research shows that in a laboratory setting, formation of chains of Tau ...
Source: NHS News Feed - November 28, 2013 Category: Consumer Health News Tags: Neurology Medical practice Source Type: news

Family fights for toddler battling cancer, more funding for childhood cancer research
It's hard to read the Facebook posts from Cannon Wiggins' family.  Because the 2-year-old Orlando boy is battling neuroblastoma, and his parents are sharing that battle in all its ugly details. They hope awareness ("this is what childhood cancer looks... (Source: OrlandoSentinel: Medical Research)
Source: OrlandoSentinel: Medical Research - November 12, 2013 Category: American Health Source Type: news

Little boy whose life was saved by a punch in the stomach: Ryan, 7, was diagnosed with cancer after a playground scrapp
Ryan Savage, from Stockton-on-Tees, was diagnosed with neuroblastoma after doctors found a tumour wrapped around his spine. (Source: the Mail online | Health)
Source: the Mail online | Health - October 25, 2013 Category: Consumer Health News Source Type: news

JCI early table of contents for Oct. 15, 2013
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Oct. 15, 2013, in the JCI: Type III TGF-beta receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma, Induction of myelodysplasia by myeloid-derived suppressor cells, Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis, Allogeneic T-cell responses are regulated by a specific miRNA-mRNA network, Chronic itch development in sensory neurons requires BRAF signaling pathways, and more. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 15, 2013 Category: Cancer & Oncology Source Type: news

Clinical trial harnesses power of natural killer cells to treat neuroblastoma
(Solving Kids' Cancer) Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer (NK) cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies. Now for the first time, scientists will combine NK cell therapy with an immunocytokine to target children with relapsed/refractory disease including those with bulky tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 10, 2013 Category: Global & Universal Source Type: news

Slide Show: Nasal Tumors
This nasal tumor slide show features pathology images of nasal neuroblastoma, rhabdomyosarcoma, melanoma, hemangiopericytoma, and lymphoma at various magnifications. (Source: Cancer Network)
Source: Cancer Network - September 12, 2013 Category: Cancer & Oncology Source Type: news

Tea Party raises money for cancer awareness
When 3-year-old Anjali died of Neuroblastoma in May 2010, Roberts wanted to find a way for her to live forever.08/19/2013 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 19, 2013 Category: Cancer & Oncology Source Type: news

Attacking the architecture of the cancer cell may help children with hard-to-treat neuroblastoma
Children with a particularly lethal cancer could benefit from potentially life-saving treatment, following breakthrough work led by researchers at the University of New South Wales (UNSW). A whole new class of drugs has been developed that, for the first time, targets the structure of the cancer cell. UNSW researchers have provided proof that the therapy is effective in two types of cancers in the animal model. They are neuroblastoma, a cancer that affects children, and melanoma. The resulting paper has been published in Cancer Research... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 19, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Children with high-risk neuroblastoma benefit from new, precise proton therapy cancer treatment
Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton therapy spared the liver and kidneys from unwanted radiation, while zeroing in on its target. "As survival rates improve for children with neuroblastoma, we need to reduce treatment-related long-term toxicities," said study leader Christine Hill-Kayser, MD, a radiation oncologist in The Children's Hospital of Philadelphia's (CHOP) Cancer Center... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 15, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Genetic map of cancer reveals trails of mutation that lead to disease
Map shows how 20 patterns of mutation drive 30 types of cancer, and could suggest strategies to prevent and treat themThe first detailed map of genetic faults that cause cancers is published today, offering profound insights into the disease.The map describes more than 20 "genetic signatures", or patterns of mutation, that alone or in combination drive 30 different types of cancer, including brain, lung, pancreas and breast tumours.Independent cancer specialists who have seen the research said it was "extremely important" and was likely to lead to new strategies to prevent and ultimately treat the disea...
Source: Guardian Unlimited Science - August 14, 2013 Category: Science Authors: Ian Sample Tags: The Guardian Genetics Biology World news Health Medical research Human biology Society Cancer UK news Science Source Type: news

Tumor suppressor may provide clues for improved treatment for neuroblastoma
Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study. Published in Developmental Cell, the findings also provide clues about how to improve the treatment of this often-incurable tumor. Neuroblastoma can appear in nervous tissue in the abdomen, chest and spine, among other regions of the body, and can spawn body-wracking metastasis... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 14, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Proton therapy offers new, precise cancer treatment for children with high-risk neuroblastoma
(Children's Hospital of Philadelphia) Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton therapy spared the liver and kidneys from unwanted radiation, while zeroing in on its target. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 13, 2013 Category: Global & Universal Source Type: news

New insights into neuroblastoma tumor suppressor may provide clues for improved treatment
(Ludwig Institute for Cancer Research) Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study. Published in Developmental Cell today, the findings also provide clues about how to improve the treatment of this often-incurable tumor. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 12, 2013 Category: Global & Universal Source Type: news

Pediatric oncologist receives grant for neuroblastoma research
 Dr. Jason Shohet, a pediatric oncologist with Baylor College of Medicine and Texas Children's Cancer Center, has received a grant from Braden's Hope for Childhood Cancer, to support his research to find treatments for high-risk neuroblastoma, an aggressive cancer of young children. (Source: Baylor College of Medicine News)
Source: Baylor College of Medicine News - July 10, 2013 Category: Universities & Medical Training Source Type: news

Autophagy Protects Neuroblastoma From Chemotherapy
Neuroblastomas are pediatric tumors that originate from cells of the embryonic nervous system. The disease can take widely varying clinical courses that range from spontaneous regression to fatal outcomes. Highly aggressive neuroblastomas rarely respond well to chemotherapy. Understanding and overcoming the resistance mechanisms of highly aggressive neuroblastomas are considered essential to the development of effective treatments. Scientists from the department headed by Professor Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 3, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Neuroblastoma: Autophagy protects from chemotherapy
(Helmholtz Association of German Research Centres) Cells can digest parts of themselves in a process called autophagy. This is a survival strategy that helps them overcome starvation and other conditions of depletion. In therapy-resistant cases of neuroblastoma, scientists from the German Cancer Research Center and Heidelberg University Hospital have now discovered an enzyme which promotes autophagy and thus protects cancer cells from treatment through chemotherapy. Blocking this enzyme might make cancer cells more sensitive to treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 1, 2013 Category: Global & Universal Source Type: news

First Stage Study Finds Potential New Drugs For Neuroblastoma
Scientists at The Institute of Cancer Research, London have made a step towards new, targeted drugs for children with the highestrisk form of a childhood cancer called neuroblastoma. In a preclinical study, published in journal Cancer Cell , researchers successfully used two potential drugs to target cancerous neuroblastoma cells with an overactive gene called MYCN. The gene plays a major role in most cases of aggressive and treatmentresistant neuroblastoma in children, as well as in some adult cancers... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 26, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Protocol for Flow Cytometric Sorting of Enriched Neuronal Cultures from iPSCs
Surface molecule profiles undergo dynamic changes in physiology and pathology, serve as markers of cellular state and phenotype and can be exploited for cell selection strategies and diagnostics. The isolation of well-defined cell subsets is needed for in vivo and in vitro applications in stem cell biology. In this technical report, the authors present an approach for defining a subset of interest in a mixed cell population by flow cytometric detection of intracellular antigens. They have developed a fully validated protocol that enables the co-detection of cluster of differentiation (CD) surface antigens on...
Source: Neuromics - June 25, 2013 Category: Neuroscience Tags: Stem Cell Research neuronal cultures induced pluripotent stem (iPS) cells CD Markers. Flow Cytometry cell sorting Neuronal Markers Neuronal Differentation nestin antibody human Source Type: news

Taking the fight to childhood cancer
Annabel Freyberg charts the advances and frustrations in the treatment of the tumour that claimed the life of her daughter, Blossom     (Source: Telegraph Health)
Source: Telegraph Health - June 24, 2013 Category: Consumer Health News Tags: children Blossom neuroblastoma Freyberg Annabel trials tumour cancer clinical Source Type: news

Girl, 15, who kept her terminal cancer a secret to lead a 'normal life' died just days after completing her GCSEs
Leah Wilby, from Great Yarmouth, beat neuroblastoma - a cancer of the nerve cells - when she was eight but it returned when she was 14. Her parents later learnt that she had achieved 10 A* to C grades in her GCSEs. (Source: the Mail online | Health)
Source: the Mail online | Health - June 20, 2013 Category: Consumer Health News Source Type: news

Phase 1 trial uses enhanced T cells to treat neuroblastoma
A phase 1 clinical trial at Baylor College of Medicine, which has received support from a pediatric cancer nonprofit organization, will use an immunotherapy approach to treating kids with neuroblastoma. (Source: Baylor College of Medicine News)
Source: Baylor College of Medicine News - June 10, 2013 Category: Universities & Medical Training Source Type: news

New Strategy For Defeating Neuroblastoma
Researchers at Karolinska Institutet in Sweden have found a promising strategy for defeating neuroblastoma - a malignant form of cancer in children - that focuses on the so-called MYCN protein. A specific chemical molecule helps to break down MYCN, which either kills the cancer cell or makes it mature into a harmless neuron. The discovery, which is published in the scientific journal PNAS, raises hopes for new and more effective treatments in the future. Neuroblastoma is the third most common form of cancer in children... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 5, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

Hope Offered By New Treatment For Neuroblastoma
Researchers at Karolinska Institutet in Sweden have found a promising strategy for defeating neuroblastoma - a malignant form of cancer in children - that focuses on the so-called MYCN protein. A specific chemical molecule helps to break down MYCN, which either kills the cancer cell or makes it mature into a harmless neuron. The discovery, which is published in the scientific journal PNAS, raises hopes for new and more effective treatments in the future. Neuroblastoma is the third most common form of cancer in children... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 5, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Potential Alternative Drug Therapies For Neuroblastoma Revealed By New Genomic Screening
Nearly two-thirds of patients with high-risk neuroblastoma - a common tumor that forms in the nerve cells of children - cannot be cured using tumor-killing cancer drugs. A study published by Cell Press in the journal Chemistry & Biology reveals a new genomic approach to screen for compounds that could inhibit tumor growth by causing cancer cells to differentiate, or convert from immature cells to more specialized cell types... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 27, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

New screening approach uncovers potential alternative drug therapies for neuroblastoma
(Cell Press) Nearly two-thirds of patients with high-risk neuroblastoma -- a common tumor that forms in the nerve cells of children -- cannot be cured using tumor-killing cancer drugs. A study published in Chemistry & Biology reveals a new genomic approach to screen for compounds that inhibit tumor growth by causing cancer cells to differentiate. Using this screening method, the researchers identified a compound that causes neuroblastoma cells to differentiate, uncovering promising new treatment strategies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 23, 2013 Category: Cancer & Oncology Source Type: news

Treatment Switch For Neuroblastoma Stem Cell Transplants
The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study being presented at the 26th annual meeting of the American Society of Pediatric Hematology Oncology in Miami April 24-27. The U.S. regimen was associated with more acute toxicity to the kidneys and liver... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 26, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Neuroblastomas Vulnerable To Novel Class Of Drugs May Be Identified By Genetic Biomarker
An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor, a difficult-to-treat, early childhood cancer, is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors, Dana-Farber/Children's Hospital Cancer Center scientists reported at the annual meeting of the American Association for Cancer Research in Washington, April 6-10. The findings (abstract 4622) were discussed in a minisymposium. The work was published in Cancer Discovery, a journal of the American Association of Cancer Research... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 11, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Pediatric cancer charities partner to fund international collaborative research
(Solving Kids' Cancer) Solving Kids' Cancer, along with UK-based charities Neuroblastoma Alliance UK, J-A-C-K, and other European organizations have aligned forces to improve access to promising clinical trials for children with high-risk neuroblastoma in North America, the UK and Europe. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 4, 2013 Category: Global & Universal Source Type: news

Neuroblastomas With Sensitivity To BET Bromodomain Inhibitors May Be Identified By Biomarker
Neuroblastoma, the most common malignant tumor of early childhood, is frequently associated with the presence of MYCN amplification, a genetic biomarker associated with poor prognosis. Researchers have determined that tumors containing MYCN amplification are sensitive to a new class of drugs, BET bromodomain inhibitors. The researchers made this discovery in a preclinical study, which was funded in part by a Stand Up To Cancer Innovative Research Grant and was published in Cancer Discovery, a journal of the American Association for Cancer Research... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 25, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Biomarker may identify neuroblastomas with sensitivity to BET bromodomain inhibitors
(American Association for Cancer Research) The MYCN gene is commonly amplified in neuroblastoma and associated with poor prognosis. A BET bromodomain inhibitor downregulated MYCN expression. The drug prolonged survival in three animal models of MYCN-amplified neuroblastoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2013 Category: Global & Universal Source Type: news

Tumors of the Central Nervous System, Volume 9
Lymphoma, Supratentorial Tumors, Glioneuronal Tumors, Gangliogliomas, Neuroblastoma in Adults, Astrocytomas, Ependymomas, Hemangiomas, and Craniopharyngiomasseries:Tumors of the Central Nervous SystemThe ninth volume in this essential series discusses key advances in our understanding of neoplasms in the human central nervous system. This publication deals with various aspects of nine separate types of brain tumors. With 70 contributors from 17 nations, this edition offers an unrivalled thoroughness and breadth of coverage that includes the very latest research results on the following ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 12, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Complete Remission Induced By Dendritic Cell Vaccine For Relapsed Neuroblastoma Patient
One year after his last treatment, a six-year-old boy with recurrent neuroblastoma is in complete remission for his high-risk metastatic cancer. Doctors reported this case study in the January 2013 issue of Pediatrics, the journal of the American Academy of Pediatrics, which was funded in part by a joint grant from the Andrew McDonough B+ Foundation, Pierce Phillips Charity and Solving Kids' Cancer. Current treatments for high-risk neuroblastoma patients include chemotherapy, radiation therapy, surgery, stem cell transplant, and immunotherapy... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Surgery failed to improve survival in advanced neuroblastoma
Simon T. J Clin Oncol. 2013;doi:10.1200/JCO.2012.45.9339. (Source: HemOncToday.com)
Source: HemOncToday.com - January 30, 2013 Category: Cancer & Oncology Source Type: news

Dendritic cell vaccine for relapsed neuroblastoma patient induces complete remission
(Solving Kids' Cancer) One year after his last treatment, a six-year-old boy with recurrent neuroblastoma is in complete remission for his high-risk metastatic cancer. Doctors reported this case study in the Jan. 2013 issue of Pediatrics, the journal of the American Academy of Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 29, 2013 Category: Global & Universal Source Type: news

Researcher Leads Large Multicenter Gene Sequencing Study Of Neuroblastoma
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutation - mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 22, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious treatment targets
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Unexpectedly, the scientists found relatively few recurrent gene mutations. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 20, 2013 Category: Science Source Type: news

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets
(Children's Hospital of Philadelphia) An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations -- mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now re-focused on how neuroblastoma tumors evolve in response to medicine and other factors. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 20, 2013 Category: Biology Source Type: news

Jamie Inglis, seven, of York, died from neuroblastoma in hospital in Tubingen, Germany
Jamie's mother Vicky Inglis, pictured here with him, said her son died peacefully in hospital in Germany after a long battle with the aggressive neuroblastoma. (Source: the Mail online | Health)
Source: the Mail online | Health - January 16, 2013 Category: Consumer Health News Source Type: news

Surgery not helpful in metastatic neuroblastoma
NEW YORK (Reuters Health) - Primary resection of stage 4 neuroblastoma does not appear to confer any benefit, German researchers say. (Source: Modern Medicine)
Source: Modern Medicine - January 2, 2013 Category: Journals (General) Source Type: news