Non-alcoholic Fatty Liver Diseases (NAFLD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Non-alcoholic fatty liver disease and sleep disorders
World J Hepatol. 2024 Mar 27;16(3):304-315. doi: 10.4254/wjh.v16.i3.304.ABSTRACTStudies have shown that non-alcoholic fatty liver disease (NAFLD) may be associated with sleep disorders. In order to explore the explicit relationship between the two, we systematically reviewed the effects of sleep disorders, especially obstructive sleep apnea (OSA), on the incidence of NAFLD, and analyzed the possible mechanisms after adjusting for confounding factors. NAFLD is independently associated with sleep disorders. Different sleep disorders may be the cause of the onset and aggravation of NAFLD. An excessive or insufficient sleep du...
Source: World Journal of Hepatology - April 5, 2024 Category: Gastroenterology Authors: Lu-Fang Bu Chong-Yu Xiong Jie-Yi Zhong Yan Xiong Dong-Ming Li Fen-Fang Hong Shu-Long Yang Source Type: research

Update in lean metabolic dysfunction-associated steatotic liver disease
CONCLUSION: MASLD is a complex disease comprising epigenetic, genetic, and metabolic factors in its pathogenesis. Results vary across populations, gender, and age. Limited data exists on clinical practice guidelines for lean patients. Future studies employing this new nomenclature can contribute to standardizing and generalizing results among lean patients with steatotic liver disease.PMID:38577539 | PMC:PMC10989317 | DOI:10.4254/wjh.v16.i3.452 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - April 5, 2024 Category: Gastroenterology Authors: Karina Sato-Espinoza Perapa Chotiprasidhi Mariella R Huaman Javier D íaz-Ferrer Source Type: research

Sex and racial disparities in non-alcoholic fatty liver disease-related cardiovascular events: National inpatient sample analysis (2019)
CONCLUSION: Increasing age and male sex link NAFLD with adverse MACCE outcomes; Native Americans and Asian Pacific Islanders face higher mortality, highlighting a need for tailored interventions and care.PMID:38576521 | PMC:PMC10989223 | DOI:10.4330/wjc.v16.i3.137 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - April 5, 2024 Category: Cardiology Authors: Rupak Desai Ali Tariq Alvi Advait Vasavada Yashwitha Sai Pulakurthi Bhavin Patel Adil Sarvar Mohammed Shreyans Doshi Ikechukwu Ogbu Source Type: research

Influence of nonalcoholic fatty liver disease on response to antiviral treatment in patients with chronic hepatitis B: A meta-analysis
CONCLUSION: Hepatic steatosis lowers the biochemical response to antiviral treatment in patients with CHB.PMID:38577526 | PMC:PMC10989305 | DOI:10.4254/wjh.v16.i3.465 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - April 5, 2024 Category: Gastroenterology Authors: Shi-Yi Liu Dian Wang Jing Liu Lu-Ping Yang Gong-Ying Chen Source Type: research

Predictive value of anthropometric and biochemical indices in non-alcoholic fatty pancreas disease: a cross-sectional study
Conclusions Weight-related and TG-related parameters are good predictors of NAFPD in all populations. BMI showed the greatest predictive potential. Multiparameter combinations appear to be a good way to predict NAFPD. (Source: BMJ Open)
Source: BMJ Open - April 5, 2024 Category: General Medicine Authors: Xiao, Y., Wang, H., Han, L., Huang, Z., Lyu, G., Li, S. Tags: Open access, Gastroenterology and hepatology Source Type: research

Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease
Conclusions This study supports the potential use of serum ferritin values for predicting the long-term prognosis of patients with MASLD. (Source: Gut)
Source: Gut - April 5, 2024 Category: Gastroenterology Authors: Armandi, A., Sanavia, T., Younes, R., Caviglia, G. P., Rosso, C., Govaere, O., Liguori, A., Francione, P., Gallego-Duran, R., Ampuero, J., Pennisi, G., Aller, R., Tiniakos, D., Burt, A., David, E., Vecchio, F., Maggioni, M., Cabibi, D., McLeod, D., Pareja Tags: Gut Hepatology Source Type: research

Cross-Talk Between Thyroid Disorders and Nonalcoholic Fatty Liver Disease: From Pathophysiology to Therapeutics
Horm Metab Res DOI: 10.1055/a-2276-7973The medical community acknowledges the presence of thyroid disorders and nonalcoholic fatty liver disease (NAFLD). Nevertheless, the interconnection between these two circumstances is complex. Thyroid hormones (THs), including triiodothyronine (T3) and thyroxine (T4), and thyroid-stimulating hormone (TSH), are essential for maintaining metabolic balance and controlling the metabolism of lipids and carbohydrates. The therapeutic potential of THs, especially those that target the TRβ receptor isoform, is generating increasing ...
Source: Hormone and Metabolic Research - April 5, 2024 Category: Endocrinology Authors: Yang, Yan Xiao, Jiyuan Qiu, Wen Jiang, Luxia Tags: Review Source Type: research

GSE202379 Single Nuclei RNA-Seq to map progression of non-alcoholic fatty liver disease (NAFLD) in patients II
Contributors : Christopher Gribben ; Vasileios Galanakis ; Alex Calderwood ; Ruben Chazarra Gil ; Irina Mohorianu ; Ludovic VallierSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNon-alcoholic fatty liver disease (NAFLD) is of increasing prevalence and concern. NAFLD can progress to non-alcoholic steatohepatitis (NASH), to cirrhosis and finally to end-stage liver disease where liver transplantation is required. We aimed to characterise this progression by performing single nuclei transcriptomic analysis of liver biopsies taken from patients across the disease spectrum. We have o...
Source: GEO: Gene Expression Omnibus - April 4, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Genes, Vol. 15, Pages 455: Relevance of PNPLA3, TM6SF2, HSD17B13, and GCKR Variants to MASLD Severity in an Egyptian Population
This study offers evidence for the association of the PNPLA3 rs738409 C&gt;G variant with MASLD among Egyptians and for the association of the PNPLA3 rs738409 G allele, the TM6SF2 rs58542926 T allele, and the GCKR rs1260326 C allele with some parameters of cardiometabolic criteria. (Source: Genes)
Source: Genes - April 4, 2024 Category: Genetics & Stem Cells Authors: Nehal Elmansoury Ahmed A. Megahed Ahmed Kamal Nefertiti El-Nikhely Marina Labane Manal Abdelmageed Ann K. Daly Ahmed Wahid Tags: Article Source Type: research

Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH
This study highlights the impact of CypD loss-of-function on the development of HCC, one of t he most severe disease outcomes. (Source: PLoS One)
Source: PLoS One - April 4, 2024 Category: Biomedical Science Authors: Winston T. Stauffer Source Type: research

Association of the habitual dietary intake with the fatty liver index and effect modification by metabotypes in the population-based KORA-Fit study
Non-alcoholic fatty liver disease (NAFLD) is an emerging threat for public health with diet being a major risk factor in disease development and progression. However, the effects of habitual food consumption o... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 4, 2024 Category: Lipidology Authors: M. Schepp, D. Freuer, N. Wawro, A. Peters, M. Heier, D. Teupser, C. Meisinger and J. Linseisen Tags: Research Source Type: research

The effects of food insecurity on hepatic steatosis and fibrosis in people with HIV
Food insecurity (FI) is a risk factor for nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis in the general population, but its impact on liver disease in people with HIV (PWH) is unknown. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - April 4, 2024 Category: Gastroenterology Authors: Ani Kardashian, Audrey Lloyd, Eduardo Vilar-Gomez, Susanna Naggie, Mark S. Sulkowski, Tinsay Woreta, Jordan E. Lake, Holly Crandall, Rohit Loomba, Laura A. Wilson, Richard K. Sterling, Sonya Heath, Samer Gawrieh, Naga P. Chalasani, Jennifer C. Price, HIV Source Type: research

Know Your Guidelines Series: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings
South Med J. 2024 Apr;117(4):206-207. doi: 10.14423/SMJ.0000000000001669.NO ABSTRACTPMID:38569610 | DOI:10.14423/SMJ.0000000000001669 (Source: Southern Medical Journal)
Source: Southern Medical Journal - April 3, 2024 Category: General Medicine Authors: Desiree C Burroughs-Ray Samantha Whitwell Nathan Williams Hira Imran Christopher D Jackson Source Type: research