Potential diagnostic markers shared between non-alcoholic fatty liver disease and atherosclerosis determined by machine learning and bioinformatic analysis
CONCLUSION: We identified RPS6KA1 and SERPINA3 as potential diagnostic markers for NAFLD and AS. The most promising marker for a diagnosis of NAFLD and AS might be RPS6KA1, whereas SERPINA3 is the most closely related gene for NASH and AS. We believe that further exploration of these core genes will reveal the etiology and a pathological relationship between NAFLD and AS.PMID:38606153 | PMC:PMC11007109 | DOI:10.3389/fmed.2024.1322102 (Source: Atherosclerosis)
Source: Atherosclerosis - April 12, 2024 Category: Cardiology Authors: Lihong Wang Wenhui He Xilin Wang Jianrong Wang Xiaojuan Wei Dongzhi Wu Yundan Wu Source Type: research

Comparison of size of the liver between patients with non-alcoholic fatty liver disease and healthy controls
CONCLUSION: The liver size of persons with fatty liver was substantially more considerable than healthy people. The size of the liver was substantially linked with sex, age, BMI, fatty liver, and hepatic steatosis grade. A straightforward way to predict fatty liver is to use ultrasonography to determine the size of the liver.PMID:38605772 | PMC:PMC11006049 | DOI:10.4103/jfmpc.jfmpc_94_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Maryam Dorostghol Mohammad M Gharibvand Mohammad G Hanafi Azim Motamedfar Source Type: research

Potential diagnostic markers shared between non-alcoholic fatty liver disease and atherosclerosis determined by machine learning and bioinformatic analysis
CONCLUSION: We identified RPS6KA1 and SERPINA3 as potential diagnostic markers for NAFLD and AS. The most promising marker for a diagnosis of NAFLD and AS might be RPS6KA1, whereas SERPINA3 is the most closely related gene for NASH and AS. We believe that further exploration of these core genes will reveal the etiology and a pathological relationship between NAFLD and AS.PMID:38606153 | PMC:PMC11007109 | DOI:10.3389/fmed.2024.1322102 (Source: Atherosclerosis)
Source: Atherosclerosis - April 12, 2024 Category: Cardiology Authors: Lihong Wang Wenhui He Xilin Wang Jianrong Wang Xiaojuan Wei Dongzhi Wu Yundan Wu Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,496 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Comparison of size of the liver between patients with non-alcoholic fatty liver disease and healthy controls
CONCLUSION: The liver size of persons with fatty liver was substantially more considerable than healthy people. The size of the liver was substantially linked with sex, age, BMI, fatty liver, and hepatic steatosis grade. A straightforward way to predict fatty liver is to use ultrasonography to determine the size of the liver.PMID:38605772 | PMC:PMC11006049 | DOI:10.4103/jfmpc.jfmpc_94_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Maryam Dorostghol Mohammad M Gharibvand Mohammad G Hanafi Azim Motamedfar Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,496 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Comparison of size of the liver between patients with non-alcoholic fatty liver disease and healthy controls
CONCLUSION: The liver size of persons with fatty liver was substantially more considerable than healthy people. The size of the liver was substantially linked with sex, age, BMI, fatty liver, and hepatic steatosis grade. A straightforward way to predict fatty liver is to use ultrasonography to determine the size of the liver.PMID:38605772 | PMC:PMC11006049 | DOI:10.4103/jfmpc.jfmpc_94_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Maryam Dorostghol Mohammad M Gharibvand Mohammad G Hanafi Azim Motamedfar Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,496 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,496 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,496 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,380 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

Association between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction: A 7-year retrospective cohort study of 3,380 adults using serial echocardiography
CONCLUSIONS: This study demonstrated that NAFLD was associated with an increased risk of LVDD in a large cohort. More severe forms of hepatic steatosis and/or significant liver fibrosis may increase the risk of developing LVDD.PMID:38608865 | DOI:10.1016/j.diabet.2024.101534 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - April 12, 2024 Category: Endocrinology Authors: Gyuri Kim Tae Yang Yu Jae Hwan Jee Ji Cheol Bae Mira Kang Jae Hyeon Kim Source Type: research

GSE260582 Mitochondrial ACSS1-K-635 acetylation mimic knock-in mice exhibit altered lipid metabolism, hepatic cell senescence, and acute non-alcoholic fatty liver [2ndSet_analysis]
Contributors : David Gius ; Guogang Xu ; Joseph Schell ; Nobuo Horikoshi ; Yidong Chen ; Zhao LaiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe generated an ACSS1-acetylation (Ac) mimic mouse, where lysine 635 was mutated to glutamine (K635Q). Male Acss1K635Q/K635Q mice were smaller with higher metabolic rate and blood acetate, and decreased liver/serum ATP and lactate levels. After a 48-hour fast, Acss1K635Q/K635Q mice presented hypothermia and liver aberrations, including enlargement, discoloration, lipid droplet accumulation, and microsteatosis – consistent with nonalco...
Source: GEO: Gene Expression Omnibus - April 12, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

GSE260581 Mitochondrial ACSS1-K-635 acetylation mimic knock-in mice exhibit altered lipid metabolism, hepatic cell senescence, and acute non-alcoholic fatty liver [1stSet_analysis]
Contributors : David Gius ; Guogang Xu ; Joseph Schell ; Nobuo Horikoshi ; Yidong Chen ; Zhao LaiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe generated an ACSS1-acetylation (Ac) mimic mouse, where lysine 635 was mutated to glutamine (K635Q). Male Acss1K635Q/K635Q mice were smaller with higher metabolic rate and blood acetate, and decreased liver/serum ATP and lactate levels. After a 48-hour fast, Acss1K635Q/K635Q mice presented hypothermia and liver aberrations, including enlargement, discoloration, lipid droplet accumulation, and microsteatosis – consistent with nonalco...
Source: GEO: Gene Expression Omnibus - April 12, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

Optimal probiotic combinations for treating nonalcoholic fatty liver disease: A systematic review and network meta-analysis
Probiotic administration is a promising therapy for improving conditions in NAFLD patients. This network meta-analysis aimed to compare and estimate the relative effects of probiotic interventions and identify the optimal probiotic species for the treatment of NAFLD (Nonalcoholic fatty liver disease) patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Yafang Yang, Ligang Yang, Jiale Wu, Jing Hu, Min Wan, Jindi Bie, Jiaxin Li, Da Pan, Guiju Sun, Chao Yang Source Type: research