Non-alcoholic Fatty Liver Diseases (NAFLD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Glucagon-Like Peptide-1: New Regulator in Lipid Metabolism
This article reviews the recent research progress of GLP-1 in lipid metabolism.PMID:38650100 | DOI:10.4093/dmj.2023.0277 (Source: Diabetes and Metabolism Journal)
Source: Diabetes and Metabolism Journal - April 23, 2024 Category: Endocrinology Authors: Tong Bu Ziyan Sun Yi Pan Xia Deng Guoyue Yuan Source Type: research

Metabolic dysfunction-associated steatotic liver disease: Evolution of the final terminology
Eur J Intern Med. 2024 Apr 22:S0953-6205(24)00173-0. doi: 10.1016/j.ejim.2024.04.013. Online ahead of print.ABSTRACTThe medical term nonalcoholic fatty liver disease (NAFLD) was coined in 1986 for a condition that has since become the most prevalent liver disorder worldwide. In the last 3 years, the global professional community launched 2 consecutive efforts to purge NAFLD from the medical dictionary and recommended new terms based on disease pathophysiology rather than distinction from similar conditions featuring liver steatosis. A consensus by renowned clinical scholars primarily residing in the Asian-Pacific region in...
Source: European Journal of Internal Medicine - April 23, 2024 Category: Internal Medicine Authors: Piero Portincasa Gyorgy Baffy Source Type: research

GSE195829 miRNA seq mouse liver HFD, PCB126, Aroclor1260 exposure
Contributors : Belinda J Petri ; Kellianne M Piell ; Bandrida Wahlang ; Kimberly Z Head ; Kalina Andreeva ; Eric C Rouchka ; Jianmin Pan ; Shesh N Rai ; Matthew C Cave ; Carolyn M KlingeSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusExposure to high fat diet (HFD) and persistent organic pollutants including polychlorinated biphenyls (PCBs) is associated with liver injury in human populations and with non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in animal models. Exposure of HFD-fed male mice to the non-dioxin-like (NDL) PCB mixture Aroclor1260 or to dio...
Source: GEO: Gene Expression Omnibus - April 23, 2024 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Mus musculus Source Type: research

Magnetic resonance elastography (MRE) outperforms acoustic force radiation impulse (ARFI) in predicting oesophageal varices in obese NAFLD cirrhosis
ConclusionIn obese NAFLD-CC, MRE-LSM is significantly higher in patients with varices. MRE combined with PC predicts EVs and HRVs with better accuracy than ARFI.Graphical abstract (Source: Abdominal Imaging)
Source: Abdominal Imaging - April 23, 2024 Category: Radiology Source Type: research

Independent Associations of Aortic Calcification with Cirrhosis and Liver Related Mortality in Veterans with Chronic Liver Disease
This study ’s purpose was to evaluate AAC and liver-related death in a cohort of Veterans with chronic liver disease (CLD).MethodsWe utilized the VISN 10 CLD cohort, a regional cohort of Veterans with the three forms of CLD: NAFLD, hepatitis C (HCV), alcohol-associated (ETOH), seen between 2008 and 2014, with abdominal CT scans (n = 3604). Associations between MAC and cirrhosis development, liver decompensation, liver-related death, and overall death were evaluated with Cox proportional hazard models.ResultsThe full cohort demonstrated strong associations of MAC and cirrhosis after adjustment: HR 2.13 (95% CI 1.63, 2.7...
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research

Blood cell parameters and risk of nonalcoholic fatty liver disease: a comprehensive Mendelian randomization study
Nonalcoholic fatty liver disease (NAFLD) is on the rise globally, and past research suggests a significant association with various blood cell components. Our goal is to explore the potential correlation betwe... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - April 23, 2024 Category: Genetics & Stem Cells Authors: Nan Zhu, Xiaoliang Wang, Huiting Zhu and Yue Zheng Tags: Research Source Type: research

DGAT2 Plays a Crucial Role to Control ESRRAPROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability
CONCLUSION: DGAT2 sustains the stability of mitochondria in hepatoma via suppressing ESRRA-PROX1 transcriptional network and hinders HCC from shifting towards glycolytic metabolism, which lowers cell proliferation.PMID:38644620 | DOI:10.4093/dmj.2023.0368 (Source: Diabetes and Metabolism Journal)
Source: Diabetes and Metabolism Journal - April 22, 2024 Category: Endocrinology Authors: Yoseob Lee Yeseong Hwang Minki Kim Hyeonuk Jeon Seyeon Joo Sungsoon Fang Jae-Woo Kim Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways
CONCLUSION: Our experiments proved that TFBP has the therapeutic effect in NAFLD, and the activation of Nrf2 and AMPK signaling pathways should make sense.PMID:38649009 | DOI:10.1016/j.bbalip.2024.159497 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 22, 2024 Category: Biochemistry Authors: Qi Wang Yunfei Wei Yeling Wang Ziyang Yu Haiyan Qin Lilei Zhao Jiaqi Cheng Bingyu Shen Meiyu Jin Haihua Feng Source Type: research