Microvascular Perfusion Imaging in Alzheimer's Disease
J Integr Neurosci. 2024 Apr 1;23(4):70. doi: 10.31083/j.jin2304070.ABSTRACTAlzheimer's disease (AD) is the leading cause of dementia worldwide and significantly impacts the essential functions of daily life and social activities. Research on AD has found that its pathogenesis is related to the extracellular accumulation of amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles in the cortical and limbic areas of the human brain, as well as cerebrovascular factors. The detection of Aβ or tau can be performed using various probes and methodologies. However, these modalities are expensive to implement and often...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Yi Song Hang Xing Zhiqi Zhang Source Type: research

Altered Resting-State Amygdalar Functional Connectivity in Primary Angle-Closure Glaucoma Patients
CONCLUSIONS: Patients with PACG exhibit extensive resting state abnormalities with respect to the FC between the amygdala and other regions of the brain, suggesting that dysregulated amygdalar FC may play a role in the pathophysiology of PACG.PMID:38682218 | DOI:10.31083/j.jin2304075 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ye Chen Yuanyuan Wang Linglong Chen Feng Ouyang Mingxue Yin Lianjiang Lv Zihe Xu Jie Liu Xianjun Zeng Source Type: research

Thalamic Alterations in Motor Neuron Diseases: A Systematic Review of MRI Findings
CONCLUSIONS: Thalamic alterations provide valuable insights into the pathophysiology and progression of MNDs. Multimodal MRI techniques are potent tools for detecting dynamic thalamic changes, indicating structural integrity, connectivity disruption, and metabolic activity.PMID:38682227 | DOI:10.31083/j.jin2304077 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Sana Mohammadi Sadegh Ghaderi Mahdi Mohammadi Zahra Najafi Asli Pashaki Rahim Khatyal Fatemeh Mohammadian Sahar Mohammadjani Source Type: research

Autoimmune encephalitis mediated by postvaccination and infection of SARS-CoV-2 in a patient with a narcolepsy type 1
CONCLUSION: The patient fulfilled the diagnostic criteria for autoimmune encephalitis with subacute onset. COVID-19 infection and vaccination could constitute a risk in a patient with narcolepsy as in this case and, could help to provide better understanding of the implication of immune-mediated processes in the pathophysiology of the diseases.PMID:38682764 | DOI:10.33588/rn.7809.2023306 (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 29, 2024 Category: Neurology Authors: R Peraita-Adrados N Bravo-Quelle Source Type: research

Thalamic Alterations in Motor Neuron Diseases: A Systematic Review of MRI Findings
CONCLUSIONS: Thalamic alterations provide valuable insights into the pathophysiology and progression of MNDs. Multimodal MRI techniques are potent tools for detecting dynamic thalamic changes, indicating structural integrity, connectivity disruption, and metabolic activity.PMID:38682227 | DOI:10.31083/j.jin2304077 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Sana Mohammadi Sadegh Ghaderi Mahdi Mohammadi Zahra Najafi Asli Pashaki Rahim Khatyal Fatemeh Mohammadian Sahar Mohammadjani Source Type: research

Altered Resting-State Amygdalar Functional Connectivity in Primary Angle-Closure Glaucoma Patients
CONCLUSIONS: Patients with PACG exhibit extensive resting state abnormalities with respect to the FC between the amygdala and other regions of the brain, suggesting that dysregulated amygdalar FC may play a role in the pathophysiology of PACG.PMID:38682218 | DOI:10.31083/j.jin2304075 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ye Chen Yuanyuan Wang Linglong Chen Feng Ouyang Mingxue Yin Lianjiang Lv Zihe Xu Jie Liu Xianjun Zeng Source Type: research

Microvascular Perfusion Imaging in Alzheimer's Disease
J Integr Neurosci. 2024 Apr 1;23(4):70. doi: 10.31083/j.jin2304070.ABSTRACTAlzheimer's disease (AD) is the leading cause of dementia worldwide and significantly impacts the essential functions of daily life and social activities. Research on AD has found that its pathogenesis is related to the extracellular accumulation of amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles in the cortical and limbic areas of the human brain, as well as cerebrovascular factors. The detection of Aβ or tau can be performed using various probes and methodologies. However, these modalities are expensive to implement and often...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Yi Song Hang Xing Zhiqi Zhang Source Type: research

Chronic non-bacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO) with a focus on pamidronate therapy
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2024 Apr 27. doi: 10.5507/bp.2024.007. Online ahead of print.ABSTRACTChronic recurrent multifocal osteomyelitis (CRMO), also called chronic nonbacterial osteomyelitis (CNO) or nonbacterial osteomyelitis (NBO), is a rare autoinflammatory bone disease of unknown etiology. However, the number of patients properly diagnosed would increase with better knowledge of the disease. In this regard, whole-body magnetic resonance imaging (WB MRI) has been found to be a better predictor of active lesions than clinical examination. Importantly, the RINBO index (radiologic index for NBO...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - April 29, 2024 Category: Biomedical Science Authors: Katerina Bouchalova Zuzana Pytelova Source Type: research

Autoimmune encephalitis mediated by postvaccination and infection of SARS-CoV-2 in a patient with a narcolepsy type 1
CONCLUSION: The patient fulfilled the diagnostic criteria for autoimmune encephalitis with subacute onset. COVID-19 infection and vaccination could constitute a risk in a patient with narcolepsy as in this case and, could help to provide better understanding of the implication of immune-mediated processes in the pathophysiology of the diseases.PMID:38682764 | DOI:10.33588/rn.7809.2023306 (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 29, 2024 Category: Neurology Authors: R Peraita-Adrados N Bravo-Quelle Source Type: research

Expert recommendations for magnetic resonance imaging of muscle disorders
CONCLUSIONS: The present work provides concrete recommendations for the indication, implementation and interpretation of muscle MRI in muscle disorders. Furthermore, it provides a possible basis for the standardisation of the measurement protocols at all clinical centres in Germany.PMID:38683354 | DOI:10.1007/s00115-024-01673-x (Source: Der Nervenarzt)
Source: Der Nervenarzt - April 29, 2024 Category: Neurology Authors: Rachel Zeng Sarah Schlaeger Matthias T ürk Thomas Baum Marcus Deschauer Rolf Janka Dimitrios Karampinos Jan Kassubek Sarah Keller-Yamamura Cornelia Kornblum Helmar Lehmann Thorsten Lichtenstein Armin M Nagel Jens Reimann Angela Rosenbohm Lara Schlaffke M Source Type: research

Nitrous oxide-induced myeloneuropathy in a Thai adolescent: a case report
Paediatr Int Child Health. 2024 Apr 29:1-4. doi: 10.1080/20469047.2024.2344403. Online ahead of print.ABSTRACTNitrous oxide, an inhalational anaesthetic, is popular with adolescents worldwide as an accessible recreational drug which induces a euphoric effect. However, chronic abuse leads to serious complications such as myeloneuropathy and bone marrow suppression by inactivation of vitamin B12. A 17-year-old girl presented with nitrous oxide-induced myeloneuropathy. She reported chronic nitrous oxide inhalation for 10 months and was admitted to the emergency department on account of repeated falls for 2 weeks. She also had...
Source: Paediatrics and international child health - April 29, 2024 Category: Pediatrics Authors: S Puetpaiboon M Meepolprapai P Saengpanit P Laohathai W Prasertsup S Khiewbanyang R Charupash O Sanmaneechai Worapant Kriengsoontornkij Source Type: research

Chronic non-bacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO) with a focus on pamidronate therapy
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2024 Apr 27. doi: 10.5507/bp.2024.007. Online ahead of print.ABSTRACTChronic recurrent multifocal osteomyelitis (CRMO), also called chronic nonbacterial osteomyelitis (CNO) or nonbacterial osteomyelitis (NBO), is a rare autoinflammatory bone disease of unknown etiology. However, the number of patients properly diagnosed would increase with better knowledge of the disease. In this regard, whole-body magnetic resonance imaging (WB MRI) has been found to be a better predictor of active lesions than clinical examination. Importantly, the RINBO index (radiologic index for NBO...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - April 29, 2024 Category: Biomedical Science Authors: Katerina Bouchalova Zuzana Pytelova Source Type: research

Thalamic Alterations in Motor Neuron Diseases: A Systematic Review of MRI Findings
CONCLUSIONS: Thalamic alterations provide valuable insights into the pathophysiology and progression of MNDs. Multimodal MRI techniques are potent tools for detecting dynamic thalamic changes, indicating structural integrity, connectivity disruption, and metabolic activity.PMID:38682227 | DOI:10.31083/j.jin2304077 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Sana Mohammadi Sadegh Ghaderi Mahdi Mohammadi Zahra Najafi Asli Pashaki Rahim Khatyal Fatemeh Mohammadian Sahar Mohammadjani Source Type: research

Microvascular Perfusion Imaging in Alzheimer's Disease
J Integr Neurosci. 2024 Apr 1;23(4):70. doi: 10.31083/j.jin2304070.ABSTRACTAlzheimer's disease (AD) is the leading cause of dementia worldwide and significantly impacts the essential functions of daily life and social activities. Research on AD has found that its pathogenesis is related to the extracellular accumulation of amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles in the cortical and limbic areas of the human brain, as well as cerebrovascular factors. The detection of Aβ or tau can be performed using various probes and methodologies. However, these modalities are expensive to implement and often...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Yi Song Hang Xing Zhiqi Zhang Source Type: research

Altered Resting-State Amygdalar Functional Connectivity in Primary Angle-Closure Glaucoma Patients
CONCLUSIONS: Patients with PACG exhibit extensive resting state abnormalities with respect to the FC between the amygdala and other regions of the brain, suggesting that dysregulated amygdalar FC may play a role in the pathophysiology of PACG.PMID:38682218 | DOI:10.31083/j.jin2304075 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ye Chen Yuanyuan Wang Linglong Chen Feng Ouyang Mingxue Yin Lianjiang Lv Zihe Xu Jie Liu Xianjun Zeng Source Type: research