Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research
Peak Resembling N-acetylaspartate (NAA) on Magnetic Resonance Spectroscopy of Brain Metastases
Conclusions: The identification of a prominent peak at 2.0 ppm could be a valuable diagnostic marker for distinguishing single ring-enhancing lesions, potentially associated with mucin-expressing metastases, offering a new avenue for diagnostic specificity in challenging cases.PMID:38674308 | PMC:PMC11052432 | DOI:10.3390/medicina60040662 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jelena Ostojic Dusko Kozic Milana Panjkovic Biljana Georgievski-Brkic Dusan Dragicevic Aleksandra Lovrenski Jasmina Boban Source Type: research
Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research
Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear
Conclusions: Age, initial tear size, and symptom duration significantly affect retear risk after arthroscopic rotator cuff repair. Occupation and type of medical insurance were also risk factors for retear. Socioeconomically vulnerable patients may be at a greater risk of retear. Proactive efforts are required to expand early access to medical care.PMID:38674286 | PMC:PMC11052191 | DOI:10.3390/medicina60040640 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jung Sub Lee Kuen Tak Suh Won Chul Shin Jung Yun Bae Tae Sik Goh Sung Won Jung Min-Hyeok Choi Suk-Woong Kang Source Type: research
Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD
DISCUSSION: FCLC-MTL is implicated in Aβ-related cortical atrophy, suggesting that LC-MTL connectivity could confer neuroprotective effects in preclinical AD.HIGHLIGHTS: Novelty-related functional magnetic resonance imaging (fMRI) LC-medial temporal lobe (MTL) connectivity links to longitudinal Aβ-dependent atrophy. This relationship extended to higher Braak stage regions with increasing Aβ burden. Longitudinal MTL atrophy mediated the LC-MTL connectivity-cognition relationship. Our findings mirror the animal data on MTL atrophy following NE signal dysfunction.PMID:38676563 | DOI:10.1002/alz.13839 (Source: The Journal o...
Source: The Journal of Alzheimers Association - April 27, 2024 Category: Psychiatry Authors: Christoph Schneider Prokopis C Prokopiou Kathryn V Papp Nina Engels-Dom ínguez Stephanie Hsieh Truley A Juneau Aaron P Schultz Dorene M Rentz Reisa A Sperling Keith A Johnson Heidi I L Jacobs Source Type: research
Bone Mesenchymal Stem Cells Inhibit Oxidative Stress-Induced Pyroptosis in Annulus Fibrosus Cells to Alleviate Intervertebral Disc Degeneration Based on Matric Hydrogels
This study was aimed to investigate the role of bone mesenchymal stem cells (BMSCs) in IVDD and the molecular mechanism. Annulus fibrosus cells (AFCs) were treated with tert-butyl hydroperoxide (TBHP) to induce oxidative stress injury. AFC biological functions were analyzed using a lactate dehydrogenase kit, enzyme-linked immunosorbent assay, flow cytometry, and western blot. The molecular mechanisms of BMSC functions were assessed using quantitative real-time PCR, western blot, immunoprecipitation (IP), co-IP, GST pull-down, and cycloheximide treatment. Furthermore, the impacts of BMSCs in IVDD progression in vivo were ev...
Source: Applied Biochemistry and Biotechnology - April 27, 2024 Category: Biochemistry Authors: Ping Sang Xuepeng Li Ziyu Wang Source Type: research
Peak Resembling N-acetylaspartate (NAA) on Magnetic Resonance Spectroscopy of Brain Metastases
Conclusions: The identification of a prominent peak at 2.0 ppm could be a valuable diagnostic marker for distinguishing single ring-enhancing lesions, potentially associated with mucin-expressing metastases, offering a new avenue for diagnostic specificity in challenging cases.PMID:38674308 | PMC:PMC11052432 | DOI:10.3390/medicina60040662 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jelena Ostojic Dusko Kozic Milana Panjkovic Biljana Georgievski-Brkic Dusan Dragicevic Aleksandra Lovrenski Jasmina Boban Source Type: research
Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear
Conclusions: Age, initial tear size, and symptom duration significantly affect retear risk after arthroscopic rotator cuff repair. Occupation and type of medical insurance were also risk factors for retear. Socioeconomically vulnerable patients may be at a greater risk of retear. Proactive efforts are required to expand early access to medical care.PMID:38674286 | PMC:PMC11052191 | DOI:10.3390/medicina60040640 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jung Sub Lee Kuen Tak Suh Won Chul Shin Jung Yun Bae Tae Sik Goh Sung Won Jung Min-Hyeok Choi Suk-Woong Kang Source Type: research
Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research
Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD
DISCUSSION: FCLC-MTL is implicated in Aβ-related cortical atrophy, suggesting that LC-MTL connectivity could confer neuroprotective effects in preclinical AD.HIGHLIGHTS: Novelty-related functional magnetic resonance imaging (fMRI) LC-medial temporal lobe (MTL) connectivity links to longitudinal Aβ-dependent atrophy. This relationship extended to higher Braak stage regions with increasing Aβ burden. Longitudinal MTL atrophy mediated the LC-MTL connectivity-cognition relationship. Our findings mirror the animal data on MTL atrophy following NE signal dysfunction.PMID:38676563 | DOI:10.1002/alz.13839 (Source: The Journal o...
Source: The Journal of Alzheimers Association - April 27, 2024 Category: Psychiatry Authors: Christoph Schneider Prokopis C Prokopiou Kathryn V Papp Nina Engels-Dom ínguez Stephanie Hsieh Truley A Juneau Aaron P Schultz Dorene M Rentz Reisa A Sperling Keith A Johnson Heidi I L Jacobs Source Type: research
Bone Mesenchymal Stem Cells Inhibit Oxidative Stress-Induced Pyroptosis in Annulus Fibrosus Cells to Alleviate Intervertebral Disc Degeneration Based on Matric Hydrogels
This study was aimed to investigate the role of bone mesenchymal stem cells (BMSCs) in IVDD and the molecular mechanism. Annulus fibrosus cells (AFCs) were treated with tert-butyl hydroperoxide (TBHP) to induce oxidative stress injury. AFC biological functions were analyzed using a lactate dehydrogenase kit, enzyme-linked immunosorbent assay, flow cytometry, and western blot. The molecular mechanisms of BMSC functions were assessed using quantitative real-time PCR, western blot, immunoprecipitation (IP), co-IP, GST pull-down, and cycloheximide treatment. Furthermore, the impacts of BMSCs in IVDD progression in vivo were ev...
Source: Applied Biochemistry and Biotechnology - April 27, 2024 Category: Biochemistry Authors: Ping Sang Xuepeng Li Ziyu Wang Source Type: research
Peak Resembling N-acetylaspartate (NAA) on Magnetic Resonance Spectroscopy of Brain Metastases
Conclusions: The identification of a prominent peak at 2.0 ppm could be a valuable diagnostic marker for distinguishing single ring-enhancing lesions, potentially associated with mucin-expressing metastases, offering a new avenue for diagnostic specificity in challenging cases.PMID:38674308 | PMC:PMC11052432 | DOI:10.3390/medicina60040662 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jelena Ostojic Dusko Kozic Milana Panjkovic Biljana Georgievski-Brkic Dusan Dragicevic Aleksandra Lovrenski Jasmina Boban Source Type: research
Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear
Conclusions: Age, initial tear size, and symptom duration significantly affect retear risk after arthroscopic rotator cuff repair. Occupation and type of medical insurance were also risk factors for retear. Socioeconomically vulnerable patients may be at a greater risk of retear. Proactive efforts are required to expand early access to medical care.PMID:38674286 | PMC:PMC11052191 | DOI:10.3390/medicina60040640 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jung Sub Lee Kuen Tak Suh Won Chul Shin Jung Yun Bae Tae Sik Goh Sung Won Jung Min-Hyeok Choi Suk-Woong Kang Source Type: research
Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research
Potential diagnostic challenges of intracerebral hemorrhage as an index presentation of metastatic choriocarcinoma: A case series
We present a case series of three young females diagnosed with metastatic choriocarcinoma after initially presenting with intracerebral hemorrhage, each demonstrating unique clinical manifestations. We aim to highlight the diagnostic considerations in the management of this infrequently encountered cause of intracerebral hemorrhage, especially in resource-constrained settings. Case 1 involved a 21-year-old woman who was initially diagnosed with intracerebral hemorrhage likely of tumoral origin from an unknown primary source. Further evaluation revealed extremely high levels of β-hCG and features suggestive of an intrauter...
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Seth Kyei ‐Fram,
Osei Yaw Asamoah,
Martin Agyei,
Priscilla Abrafi Opare‐Addo Tags: CASE REPORT Source Type: research
